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Categories: Biology: Cell Biology, Biology: Molecular

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The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers resolved outstanding questions regarding the origin of small regulatory genes, and described a mechanism that creates their DNA palindromes. Under suitable circumstances, these palindromes evolve into microRNA genes.

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A recent study has revealed that an unlikely event, occurring over 12 million years ago played an important role in shaping one of Canada's most damaging invasive species. Zebra and quagga mussels, belonging to the Dreissenid family, are widespread freshwater invasive species throughout North America that present a significant danger to native ecosystems by competing for resources. Using a fibrous anchor called a byssus, Dreissenid mussels contribute to biofouling on surfaces and obstruct intake structures in power stations and water treatment plants.

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Paleontologists are getting a glimpse at life over a billion years in the past based on chemical traces in ancient rocks and the genetics of living animals. New research combines geology and genetics, showing how changes in the early Earth prompted a shift in how animals eat.

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A new study demonstrates that the human gut microbiome may be a factor in breast health. 

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Dental plaque, gut bacteria and the slippery sheen on river rocks are all examples of biofilms, organized communities of microorganisms that colonize our bodies and the world around us. A new study reveals exactly how growing biofilms shape their environments and fine-tune their internal architecture to fit their surroundings. The findings may have implications for a wide variety of applications, from fighting disease to engineering new types of living active materials.

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Researchers investigated a novel strategy to neutralize human noroviruses. They tested the ability of tiny antibodies produced by llamas, called nanobodies, to effectively neutralize human norovirus infection in the lab. The unexpected findings reveal that nanobodies could be developed as a therapeutic agent against human norovirus.

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A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research has found.  The discovery could pave the way for new and more effective drugs, without the nasty side effects of existing treatments. In addition to helping to manage severe autoimmune conditions, the breakthrough could also help treat all types of cancer.  

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Researchers have shown that an influx of water and ions into immune cells allows them to migrate to where they're needed in the body.  

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Scientists' debut 'reverse metabolomics,' a groundbreaking approach to advancing microbiome research. They use the technique to discover hundreds of new human molecules, and a new biomarker and therapeutic target for inflammatory bowel disease.

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Pregnant women eating modern diets are missing key nutrients needed for them and their babies, and this could get worse with the move to plant-based foods. Scientists surveying more than 1,700 women found most were missing vitamins usually found in meat and dairy, including B12, B6 and D, folic acid and riboflavin which are essential for the development of fetuses in the womb.

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Researchers have uncovered the intricate molecular mechanism used by parasitic phytoplasma bacteria, known for inducing 'zombie-like' effects in plants.

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Researchers have discovered that electric eels can alter the genes of tiny fish larvae with their electric shock. Their findings help to better understand electroporation, a method by which genes can be transported using electricity.

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Aquaporins, which move water through membranes of plant cells, were not thought to be able to permeate sugar molecules, but researchers have observed sucrose transport in plant aquaporins for the first time, challenging this theory.

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A new sensor on the submersible Alvin discovered reactive oxygen species for the first time in deep-sea corals, broadening our understanding of fundamental coral physiology.

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Pregnancy brings a rise in pancreatic beta cells -- the cells that produce insulin. Shortly after birth, these cells return to their normal levels. The mechanisms behind this process had remained a mystery. But now a research group has revealed that white blood cells called macrophages 'eat' these cells. 

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Scientists have amassed genome data for dozens of 'magic mushroom' isolates and cultivars, with the goal to learn more about how their domestication and cultivation has changed them. The findings may point the way to the production of intriguing new cultivars, say the researchers.

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While we often think of diseases as caused by foreign bodies -- bacteria or viruses -- there are hundreds of diseases affecting humans that result from errors in cellular production of its proteins. A team of researchers recently leveraged the power of cutting-edge technology, including an innovative technique called glycoproteomics, to unlock the carbohydrate-based code that governs how certain classes of proteins form themselves into the complex shapes necessary to keep us healthy.

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A mouse study found that the drug ketamine can alter the brain's dopamine system, boosting the case for more targeted medical use.

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Researchers have developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease. MAbID offers new insights into how these mechanisms work together or against each other.

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New research has revealed a previously unknown process through which pathogens are able to defeat a cell's defense mechanisms with physical force. The discovery represents a potential game-changer in the fight against intracellular pathogens, which cause infectious diseases such as tuberculosis, malaria and chlamydia.