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Categories: Biology: Evolutionary, Biology: Molecular
Published AI can improve Alzheimer's treatment through the 'gut-brain axis'



Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's disease.
Published Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases



In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.
Published Protein network dynamics during cell division



An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.
Published The enemy within: How pathogens spread unrecognized in the body



Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.
Published Breakthrough rice bran nanoparticles show promise as affordable and targeted anticancer agent



Plant-derived nanoparticles have demonstrated significant anticancer effects. Researchers recently developed rice bran-derived nanoparticles (rbNPs) that efficiently suppressed cell proliferation and induced programmed cell death of only cancer cells. Furthermore, rbNPs successfully suppressed the growth of tumors in mice having aggressive adenocarcinoma in their peritoneal cavity, without any adverse effects. Given their low production costs and high efficacy, rbNPs hold great promise for developing affordable and safe anticancer agents.
Published Key protein regulates immune response to viruses in mammal cells



Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.
Published Light show in living cells



Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.
Published Why can zebrafish regenerate damaged heart tissue, while other fish species cannot?



A heart attack will leave a permanent scar on a human heart, yet other animals, including zebrafish, can clear cardiac scar tissue and regrow damaged muscle as adults. Biologists sheds new light on how zebrafish heal heart tissue by comparing how this species responds to heart injury with medaka, a fish species that cannot regenerate cardiac tissue.
Published Marine microbial populations: Potential sensors of the global change in the ocean



Animal and plant populations have been extensively studied, which has helped to understand ecosystem processes and evolutionary adaptations. However, this has not been the case with microbial populations due to the impossibility of isolating, culturing and analyzing the genetic content of the different species and their individuals in the laboratory. Therefore, although it is known that populations of microorganisms include a great diversity, this remains largely uncharacterized.
Published RNA's hidden potential: New study unveils its role in early life and future bioengineering



The origin of life continues to remain a matter of debate. The ribonucleic acid (RNA) world hypothesis proposes that 'ribozymes' which store genetic information and possess catalytic functions may have supported the activities of early life forms. Now, researchers explore how RNA elongation is regulated allosterically, shedding light on its impact on early life processes and offering insights into the fabrication of arbitrary RNA nanostructures with various modern applications.
Published Mountain chickadees have remarkable memories. A new study explains why



Mountain chickadees have among the best spatial memory in the animal kingdom. New research identifies the genes at play and offers insight into how a shifting climate may impact the evolution of this unique skill.
Published Solving a mini mystery of cell division



Trying to hit a target size before dividing seems like the best strategy for maintaining a precise cell size, but bacteria don't do that. Now we know why.
Published Plant sensors could act as an early warning system for farmers



Using a pair of sensors made from carbon nanotubes, researchers discovered signals that help plants respond to stresses such as heat, light, or attack from insects or bacteria. Farmers could use these sensors to monitor threats to their crops, allowing them to intervene before the crops are lost.
Published Tracking a protein's fleeting shape changes



Researchers have developed a powerful, new technique to generate 'movies' of changing protein structures and speeds of up to 50 frames per second.
Published Researchers uncover human DNA repair by nuclear metamorphosis



Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.
Published New butterfly species created 200,000 years ago by two species interbreeding



Researchers have shown that an Amazonian butterfly is a hybrid species, formed by two other species breeding together almost 200,000 years ago. Researchers have shown that an Amazonian butterfly is a hybrid species, formed by two other species breeding together almost 200,000 years ago.
Published Reproductive success improves after a single generation in the wild for descendants of some hatchery-origin Chinook salmon



Researchers who created 'family trees' for nearly 10,000 fish found that first-generation, wild-born descendants of hatchery-origin Chinook salmon in an Oregon river show improved fitness.
Published Seed ferns: Plants experimented with complex leaf vein networks 201 million years ago



According to a research team led by palaeontologists, the net-like leaf veining typical for today's flowering plants developed much earlier than previously thought, but died out again several times. Using new methods, the fossilized plant Furcula granulifer was identified as such an early forerunner. The leaves of this seed fern species already exhibited the net-like veining in the late Triassic (around 201 million years ago).
Published Twisted pollen tubes induce infertility



Plants with multiple sets of chromosomes, known as polyploids, are salt-tolerant or drought-resistant and often achieve higher yields. However, newly formed polyploid plants are often sterile or have reduced fertility and are unsuitable for breeding resistant lines. The reason is that the pollen tube in these plants grows incorrectly, which keeps fertilization from taking place. Pollen tube growth is mainly controlled by two genes that could be useful in crop breeding.
Published How blue-green algae manipulate microorganisms



A research team discovers previously unknown gene that indirectly promotes photosynthesis Protein regulator NirP1 influences the coordination of the nitrogen and carbohydrate metabolism 'Such protein regulators could in future be deployed in 'green' and 'blue' biotechnology for targeted control of the metabolism,' says geneticist.