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Categories: Biology: Evolutionary, Biology: Molecular
Published Macrophages 'eat' insulin-producing cells to regulate insulin after mice have given birth
(via sciencedaily.com) Original source Pregnancy brings a rise in pancreatic beta cells -- the cells that produce insulin. Shortly after birth, these cells return to their normal levels. The mechanisms behind this process had remained a mystery. But now a research group has revealed that white blood cells called macrophages 'eat' these cells.
Published Researchers have cracked the cellular code on protein folding, offering hope for new therapeutic avenues for many diseases
(via sciencedaily.com) Original source While we often think of diseases as caused by foreign bodies -- bacteria or viruses -- there are hundreds of diseases affecting humans that result from errors in cellular production of its proteins. A team of researchers recently leveraged the power of cutting-edge technology, including an innovative technique called glycoproteomics, to unlock the carbohydrate-based code that governs how certain classes of proteins form themselves into the complex shapes necessary to keep us healthy.
Published Earliest-known fossil mosquito suggests males were bloodsuckers too
(via sciencedaily.com) Original source Researchers have found the earliest-known fossil mosquito in Lower Cretaceous amber from Lebanon. What's more, the well-preserved insects are two males of the same species with piercing mouthparts, suggesting they likely sucked blood. That's noteworthy because, among modern-day mosquitoes, only females are hematophagous, meaning that they use piercing mouthparts to feed on the blood of people and other animals.
Published Crocodile family tree mapped: New light shed on croc evolution
(via sciencedaily.com) Original source Around 250 million years ago, 700 species of reptiles closely related to the modern-day crocodile roamed the earth, now new research reveals how a complex interplay between climate change, species competition and habitat can help explain why just 23 species of crocodile survive today.
Published New technique efficiently offers insight into gene regulation
(via sciencedaily.com) Original source Researchers have developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease. MAbID offers new insights into how these mechanisms work together or against each other.
Published Unlocking the secret strength of marine mussels
(via sciencedaily.com) Original source How do you create strong, yet quick-release connections between living and non-living tissues? This is a question that continues to puzzle bioengineers who aim to create materials that bond together for advanced biomedical applications. Looking to nature for inspiration, this research zeroed in on the marine mussel byssus, a fibrous holdfast, which these bivalve mollusks use to anchor themselves in seashore habitats.
Published Shedding light on the synthesis of sugars before the origin of life
(via sciencedaily.com) Original source Pentoses are essential carbohydrates in the metabolism of modern lifeforms, but their availability on early Earth is unclear since these molecules are unstable. Now, researchers reveal a chemical pathway compatible with early Earth conditions, by which C6 aldonates could have acted as a source of pentoses without the need for enzymes. Their findings provide clues about primitive biochemistry and bring us closer to understanding life's origin.
Published Genomic study sheds light on how carnivorous Asian pitcher plants acquired signature insect trap
(via sciencedaily.com) Original source Scientists sequenced the genome of the East Asian pitcher plant, Nepenthes gracilis, a species of carnivorous plant related to Venus flytraps, as well as sundews, beets and spinach.
Published Snake skulls show how species adapt to prey
(via sciencedaily.com) Original source By studying the skull shapes of dipsadine snakes, researchers have found how these species of snakes in Central and South America have evolved and adapted to meet the demands of their habitats and food sources.
Published A mixed origin made maize successful
(via sciencedaily.com) Original source Maize is one of the world's most widely grown crops. It is used for both human and animal foods and holds great cultural significance, especially for indigenous peoples in the Americas. Yet despite its importance, the origins of the grain have been hotly debated for more than a century. Now new research shows that all modern maize descends from a hybrid created just over 5000 years ago in central Mexico, thousands of years after the plant was first domesticated.
Published Armed to the hilt: Study solves mystery behind bacteria's extensive weaponry
(via sciencedaily.com) Original source A new study tackles the mystery of why bacteria often carry diverse ranges of weapons. The findings show that different weapons are best suited to different competition scenarios. Short-range weapons help bacteria to invade established communities; long-range weapons are useful once established.
Published A new bacterial species from a hydrothermal vent throws light on their evolution
(via sciencedaily.com) Original source A new bacterial species discovered at the deep-sea hydrothermal vent site 'Crab Spa' provides a deeper understanding of bacterial evolution.
Published Clever dosage control mechanism of biallelic genes
(via sciencedaily.com) Original source Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an 'anti-monoallelic' factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.
Published Key protein in blood vessel's growth identified
(via sciencedaily.com) Original source New research identifies the class II PI3K-C2b protein, a member of the PI3 family of kinases, as one of the key regulators of blood vessels growth in humans and other mammals. Mutations in these family of proteins may lead to vascular malformations and the precise understanding of the whole process is instrumental in opening the door to new therapeutic approaches in the future.
Published Releasing brakes on biocatalysis
(via sciencedaily.com) Original source Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. In order to make this hydrogen production efficient, researchers are trying to identify and eliminate possible limiting factors. These include formaldehyde, which occurs naturally as a metabolic product in cells and inhibits the particularly efficient [FeFe] hydrogenase.
Published The venom preceded the stinger: Genomic studies shed light on the origins of bee venom
(via sciencedaily.com) Original source Bees, wasps and ants belong to the Hymenoptera order and inject a whole cocktail of venomous ingredients when they sting. Despite their tremendous ecological and economic importance, little was previously known about the origins of their venom. Through extensive genomic studies, a team of researchers has now discovered that typical venomous components were already present in the earliest ancestors of Hymenoptera and must therefore have evolved before the stingers of bees and other insects. What's more, and contrary to previous assumptions, the gene for the venom melittin is found solely in bees.
Published Landscape dynamics determine the evolution of biodiversity on Earth
(via sciencedaily.com) Original source A landmark study into the geological timescale distribution of sediment and nutrients over 500 million years shows that species biodiversity on Earth is driven by landscape dynamics.
Published Tracing the evolution of the 'little brain'
(via sciencedaily.com) Original source The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans. A research team has now generated comprehensive genetic maps of the development of cells in the cerebella of human, mouse and opossum. Comparisons of these maps reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development.
Published A spectrum of possibilities: Insights into the evolution of far-red light photosynthesis
(via sciencedaily.com) Original source Scientists have unraveled the evolutionary journey of a unique type of photosynthesis that allows some bacteria to harness far-red light, a region beyond the visible spectrum. This discovery could pave the way for engineering plants with enhanced light absorption capabilities and has implications for our search for extraterrestrial life.
Published Scientists harness flower 'super power' to pave the way for new drug treatments
(via sciencedaily.com) Original source Researchers have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells.