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Categories: Biology: Evolutionary, Biology: Molecular
Published Giant dinosaur carcasses might have been important food sources for Jurassic predators



Carnivorous dinosaurs might have evolved to take advantage of giant carcasses, according to a new study.
Published First mice engineered to survive COVID-19 like young, healthy humans



Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published Where is a sea star's head? Maybe just about everywhere



A new study that combines genetic and molecular techniques helps solve the riddle of sea star (commonly called starfish) body plans, and how sea stars start life with bilateral body symmetry -- just like humans -- but grow up to be adults with fivefold 'pentaradial' symmetry.
Published How the fish got its shoulder



A new analysis of the bones and muscles in ancient fish gives new clues about how the shoulder evolved in animals -- including us.
Published New Nijmegen method reveals hidden genetic variations



Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient diagnoses and may also lead to the discovery of as yet unknown disease genes.
Published Plastic-eating bacteria turn waste into useful starting materials for other products



Mountains of used plastic bottles get thrown away every day, but microbes could potentially tackle this problem. Now, researchers report that they've developed a plastic-eating E. coli that can efficiently turn polyethylene terephthalate (PET) waste into adipic acid, which is used to make nylon materials, drugs and fragrances.
Published Scientists create special 'telomouse' with human-like telomeres



Researchers introduce the 'Telomouse'. By making a subtle genetic alteration in standard lab mice, they've made the mouse telomeres, which protect the chromosome ends, more closely resemble those in humans. The Telomouse model, developed by incorporating a genetic variation from a mouse species with naturally shorter telomeres, provides a valuable resource for in-depth aging and cancer research. This discovery promises to reveal new insights into the genetics of aging and may contribute to enhanced longevity and well-being.
Published Intestinal bacteria metabolite promotes capture of antigens by dendritic cells



Dendritic cells are immune cells that capture and present antigens to T cells, activating an immune response. Researchers have discovered that short-chain fatty acids produced by intestinal bacteria regulate a crucial step in this process, the extension of dendritic 'arms.' This breakthrough finding could potentially lead to the development of disease prevention strategies involving beneficial bacteria and new drugs targeting the regulation of dendritic cell function.
Published Controlling organoids with light



Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.
Published Evolutionary chance made this bat a specialist hunter



It is generally believed that, for millions of years, bats and the insects they hunt at night have adapted to each other in an evolutionary arms race to become better at finding or avoiding each other. Now, a new study shows that this may not be the case at all.
Published Protein root discovery seals future of climate-proof plants



Researchers have discovered a protein that seals plant roots to regulate the uptake of nutrients and water from the soil, the discovery could help develop climate proof crops that require less water and chemical fertilizers.
Published Researchers solve protein mystery



Researchers have uncovered that proteins use a common chemical label as a shield to protect them from degradation, which in turn affects motility and aging.
Published Genetic methods enable the use of fossil lipids as biomarkers for oxygen-producing primordial bacteria



Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems. For a long time, a certain type of fossil lipid, so-called 2-methylhopanes, was considered to be an important biomarker for Cyanobacteria in sediments, some of which are hundreds of millions of years old. However, this came into doubt when it turned out that not only Cyanobacteria but also Alphaproteobacteria are genetically capable of producing these lipids.
Published Mammalian cells may consume bacteria-killing viruses to promote cellular health



Bacteriophages, also called phages, are viruses that infect and kill bacteria, their natural hosts. But from a macromolecular viewpoint, phages can be viewed as nutritionally enriched packets of nucleotides wrapped in an amino acid shell. A study suggests that mammalian cells internalize phages as a resource to promote cellular growth and survival.
Published Fruit, nectar, bugs and blood: How bat teeth and jaws evolved for a diverse dinnertime



Noctilionoid bat species evolved wildly different faces as they adapted to exploit diverse food sources -- including insects, fruit, nectar, blood and fish. New research shows that those adaptations include dramatic, but also consistent, modifications to tooth number, size, shape and position.
Published Discovery of three novel minorisa species, the smallest predatory marine picoplankton



Researchers have made a significant discovery by identifying and characterizing three novel species within the Minorisa genus of marine picoplankton. Before this study, only one species of Minorisa was recognized. This finding reveals previously unseen diversity of Minorisa, thereby enhancing species identification and our understanding of its ecological functions in marine ecosystems.
Published Membrane transporter ensures mobility of sperm cells



Special proteins -- known as membrane transporters -- are key to the mobility of sperm cells. A research team has, with the aid of cryo-electron microscopy, succeeded in decoding the structure of such a transporter and its mechanism. These findings will enable a better understanding of the molecular foundations of reproductive capacity and could, in the long term, contribute to developing new approaches to treating fertility disorders and new methods of specific contraception.
Published Analysis finds diversity on the smallest scales in sulfur-cycling salt marsh microbes



Scientists have discovered that even among the sulfur-cycling microbes that are responsible for the 'rotten egg gas' smell in salt marsh air, diversity extends all the way to genomes and even to individual nucleotides.
Published Defect in fruit fly respiratory system may provide insights into human aortic aneurysms



A team of researchers has gained new insights into the respiratory system of fruit flies -- the so-called tracheal system -- which could be important for future research into aneurysms. Scientists carried out genetic, cell biological and biochemical studies on Drosophila embryos. They found that the cells in the fruit fly's tracheal system are connected to the extracellular matrix by the proteins Dumpy and Piopio.
Published How eggs of the Zika-carrying mosquito survive desiccation



Eggs of the mosquito that carries Zika virus can tolerate extended desiccation by altering their metabolism, according to a new study. The finding offers potential new ways to control the spread of this mosquito.