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Categories: Biology: Molecular, Environmental: Biodiversity
Published Saved from extinction, Southern California's Channel Island Foxes now face new threat to survival
(via sciencedaily.com) Original source Starting in the 1990s, Island Fox populations began to dwindle due to an outbreak of canine distemper and an increase in attacks by golden eagles. Some islands saw their population drop to as low as 15 individuals, but conservation efforts by the Federal government restored numbers by 2017. A new study reveals a worrying decrease in genetic diversity within the species, signaling a new threat to the Channel Islands foxes' survival. The decrease in genetic diversity reduces the foxes' ability to adapt to future challenges, such as climate change and introduced pathogens, putting their survival at risk once again. Although the foxes have low genetic diversity, they possess diverse gut microbiomes that could help them cope with environmental changes.
Published Researchers use 'natural' system to identify proteins most useful for developing an effective HIV vaccine
(via sciencedaily.com) Original source Scientists have spent years trying to develop an effective HIV vaccine, but none have proven successful. Based on findings from a recently published study, a research team may have put science one step closer to that goal.
Published Light conveyed by the signal transmitting molecule sucrose controls growth of plant roots
(via sciencedaily.com) Original source Researchers shows how information about the quantity of absorbed light passes from the leaves to the roots. Photosynthetic sucrose not only supplies roots with carbohydrates but also acts as a signal transmitter for light-dependent root architecture.
Published Scientists unveil RNA-guided mechanisms driving cell fate
(via sciencedaily.com) Original source The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques.
Published Protein-based nano-'computer' evolves in ability to influence cell behavior
(via sciencedaily.com) Original source The first protein-based nano-computing agent that functions as a circuit has been created. The milestone puts them one step closer to developing next-generation cell-based therapies to treat diseases like diabetes and cancer.
Published River erosion can shape fish evolution
(via sciencedaily.com) Original source A new study of the freshwater greenfin darter fish suggests river erosion can be a driver of biodiversity in tectonically inactive regions.
Published Researchers successfully induce primate oocytes in the lab
(via sciencedaily.com) Original source The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.
Published The fast and the fibrous: Developing the muscles you need for speed
(via sciencedaily.com) Original source Researchers have identified the role of the large Maf transcription factor family in regulating fast twitch muscle fibers. A mouse model lacking Maf expression in the skeletal muscles exhibited a significant loss of type IIb myofibers, a subtype of fast twitch fibers. Overexpression of large Mafs promoted type IIb muscle fiber induction. The large Maf family may represent potential targets for developing treatments for muscular disorders involving fast twitch fibers.
Published Deep sea surveys detect over five thousand new species in future mining hotspot
(via sciencedaily.com) Original source There is a massive, mineral-rich region in the Pacific Ocean -- about twice the size of India -- called the Clarion-Clipperton Zone (CCZ), which has already been divided up and assigned to companies for future deep-sea mining. To better understand what may be at risk once companies start mining, a team of biologists has built the first 'CCZ checklist' by compiling all the species records from previous research expeditions to the region. Their estimates of the species diversity of the CCZ included a total of 5,578 different species, an estimated 88% - 92% of which are entirely new to science.
Published How tasty is the food?
(via sciencedaily.com) Original source A hormone and specialized brain cells regulate feeding behavior in mice.
Published Global macrogenetic map of marine habitat-forming species
(via sciencedaily.com) Original source Species known as marine habitat-forming species -- gorgonians, corals, algae, seaweeds, marine phanerogams, etc.-- are organisms that help generate and structure the underwater landscapes. These are natural refuges for other species, and provide biomass and complexity to the seabeds. But these key species in marine ecosystems are currently threatened by climate change and other perturbations derived from human activity. Now, a study warns that even in the marine protected areas (MPAs) the genetic diversity of structural species is not protected, although it is essential for the response and adaptation of populations to changes that alter the natural environment.
Published Where do our limbs come from?
(via sciencedaily.com) Original source Scientists have uncovered new clues about the origin of paired appendages -- a major evolutionary step that remains unresolved and highly debated.
Published A look into the heart of cellular waste disposal
(via sciencedaily.com) Original source Researchers reveal how a nanomachine takes care of cleaning up inside the cell.
Published Engineers create bacteria that can synthesize an unnatural amino acid
(via sciencedaily.com) Original source Researchers have engineered bacteria to synthesize an amino acid that contains a rare functional group that others have shown to have implications in the regulation of our immune system. The researchers also taught a single bacterial strain to create the amino acid and place it at specific sites within target proteins. These findings provide a foundation for developing unique vaccines and immunotherapies in the future.
Published Researchers find new mechanism for sodium salt detoxification in plants
(via sciencedaily.com) Original source A team of researchers has found a mechanism in thale cress (Arabidopsis thaliana) which enables plants to provide protection against salt stress for their sensitive stem cells in the meristem at the root tip.
Published A multiomics approach provides insights into flu severity
(via sciencedaily.com) Original source Researchers were able to identify changes in the accessibility (that is, the 'readability') of transposable elements. To do this, the researchers used an approach combining various sets of multiomics data, which characterize and quantify collections of biomolecules in cells or organisms. One was the transcriptome, which consists of all copies of RNA transcribed from DNA in the cell. The other was the epigenome, which is the collection of chemical changes to DNA that modify gene expression. An advantage of this multiomics approach is that they were able to identify families of transposable elements with changes in accessibility, which would have likely been missed by previous approaches.
Published Designing synthetic receptors for precise cell control
(via sciencedaily.com) Original source Scientists have developed a groundbreaking new technique for engineering biosensors that respond sensitively to specific biomolecules, enhancing cell migration and targeting in cancer treatment. The findings could lead to more precise control over cellular processes for a wide range of therapeutic applications.
Published Under control to the very end -- how our cells kill themselves
(via sciencedaily.com) Original source Every day, millions of cells die in our body. Other than generally assumed, cells do not simply burst at the end of their lives but rather, a specific protein serves as a breaking point for cell membrane rupture. Researchers have now been able to elucidate the exact mechanism at the atomic level.
Published A guide through the genome
(via sciencedaily.com) Original source Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests. One of the greatest challenges in modern plant research is to identify the differences in genetic information that are responsible for this variation.
Published How plants use sugar to produce roots
(via sciencedaily.com) Original source Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. Botanists have demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to the research team leader.