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Categories: Biology: Molecular, Environmental: Biodiversity

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A parasite which has devastating impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells -- providing clues to their function and helping to identify potential drug targets.

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MitoQ, a mitochondrial antioxidant that is available to the public as a diet supplement, was found in a mouse study to reverse the detrimental effects that HIV and antiretroviral therapy (ART) have on mitochondria in the brain, heart, aorta, lungs, kidney and liver.

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A group of natural history museums has mapped the total collections from 73 of the world's largest natural history museums in 28 countries. This is the first step of an ambitious effort to inventory global holdings that can help scientists and decision makers find solutions to urgent, wide-ranging issues such as climate change, food insecurity, human health, pandemic preparedness, and wildlife conservation.

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Researchers have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB. If this natural process can be harnessed with new treatments, it could present an alternative to, or improve use of antibiotics, especially where bacteria have become resistant to existing drugs.

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Researchers have uncovered a key role for a new type of cell in touch detection in the skin of the fruit fly.

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Damage in the human genome can be repaired. But this works better in germ cells, sperm and eggs, than in normal body cells. Responsible for this is the DREAM protein complex, which prevents the activation of all available repair mechanisms. A research team has now shown that normal body cells can also be repaired better once this complex has been deactivated. In the long run, the scientists hope to develop better therapies to prevent cancer and aging-associated diseases.

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At least 80% of sites identified as being internationally important for biodiversity on land currently contain infrastructure -- of which more than 75% contain roads. In the future, more sites that are important for biodiversity could contain powerplants, mines and oil and gas infrastructure.

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Scientists have significantly advanced the race to control plant responses to temperature on a rapidly warming planet. Key to this breakthrough is miRNA, a molecule nearly 200,000 times smaller than the width of a human hair.

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Some plants can survive months without water, only to turn green again after a brief downpour. A recent study shows that this is not due to a 'miracle gene.' Rather, this ability is a consequence of a whole network of genes, almost all of which are also present in more vulnerable varieties.

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Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. Researchers have now described a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans. These effector memory B cells appear to be poised for a rapid serum antibody response upon secondary challenge one year later.

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By combining lab experiments and mathematical modelling, researchers have found a way to predict the movement of species that could guide conservation efforts to reconnect fragmented habitats.

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Researchers have developed a handheld sensor that tests perspiration for cortisol and provides results in eight minutes, a key advance in monitoring a hormone whose levels are a marker for many illnesses including various cancers.

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Researchers have 'hacked' the earliest stages of photosynthesis, the natural machine that powers the vast majority of life on Earth, and discovered new ways to extract energy from the process, a finding that could lead to new ways of generating clean fuel and renewable energy.

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Deleting a gene that promotes magnesium transport into mitochondria (which are cells' power plants) resulted in more efficient metabolism of sugar and fat in the energy centers. The result: skinny, healthy mice. Now the research team, has developed a small-molecule drug that accomplishes the same effect in mice.

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Researchers find stem cells use a surprising system for discarding misfolded proteins. This unique pathway could be the key to maintaining long-term health and preventing age-related blood and immune disorders.

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When exotic species such as parrots, snakes, monkeys, or aquarium fishes are kept as pets, this may lead to unsustainable trade and impact negatively the conservation of these species globally. Understanding what drives demand among keepers may help inform adequate conservation strategies to address unsustainable trade.

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Research in languages other than English is critically important for biodiversity conservation and is shockingly under-utilized internationally, according to an international research team.

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Fewer parasites in U.S. waters might be seen by many as a good thing, but a biologist says the trend signals potential danger for fish and other wildlife.

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Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway. Researchers now characterize how the enzyme PCYT2 affects muscle health in disease and aging in laboratory mouse models.

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A global mapping project has revealed the major stressors placed upon global coastlines by human activity.