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Categories: Biology: Molecular, Environmental: Biodiversity
Published Mountain forests are being lost at an accelerating rate, putting biodiversity at risk
(via sciencedaily.com) More than 85% of the world's bird, mammal, and amphibian species live in mountains, particularly in forest habitats, but researchers report that these forests are disappearing at an accelerating rate. Globally, we have lost 78.1 million hectares (7.1%) of mountain forest since 2000 -- an area larger than the size of Texas. Much of the loss occurred in tropical biodiversity hotspots, putting increasing pressure on threatened species.
Published New study counts the environmental cost of managing Japanese knotweed
(via sciencedaily.com) New research has looked at the long-term environmental impact of different methods to control Japanese knotweed. Different ways of trying to control the invasive species have developed over the years but now, as sustainability becomes increasingly important, understanding the effect of these management methods is vital.This new study examines at the entire life cycle and long-term impacts of different management approaches.
Published Discovery of an unexpected function of blood immune cells: Their ability to proliferate
(via sciencedaily.com) The ability of a cell to divide, to proliferate, is essential for life and gives rise to the formation of complex organisms from a single cell. It also allows the replacement of used cells from a limited number of 'stem' cells, which then proliferate and specialize. In cancer, however, cell proliferation is no longer controlled and becomes chaotic. Researchers have discovered that, in a healthy individual, certain blood immune cells, the monocytes, also have this ability to proliferate, with the aim to replace tissue macrophages, which are essential for the proper functioning of our body.
Published How can we tackle the biggest challenges? Ask a plant
(via sciencedaily.com) Without plants, we'd have no air to breathe or food to eat, yet plant science lingers in the shadowy wings while other fields take center stage. With the goal of shining the spotlight on plants, a new study presents the field's top 100 most pressing questions for research to address the greatest challenges facing humanity.
Published An extra X chromosome-linked gene may explain decreased viral infection severity in females
(via sciencedaily.com) It has long been known that viral infections can be more severe in males than females, but the question as to why has remained a mystery -- until possibly now. Researchers have found that female mouse and human Natural Killer cells have an extra copy of an X chromosome-linked gene called UTX. UTX acts as an epigenetic regulator to boost NK cell anti-viral function, while repressing NK cell numbers.
Published Loss of Menin helps drive the aging process, and dietary supplement can reverse it in mice
(via sciencedaily.com) Decline in the hypothalamic Menin may play a key role in aging, according to a new study. The findings reveal a previously unknown driver of physiological aging, and suggest that supplementation with a simple amino acid may mitigate some age-related changes.
Published How fishermen benefit from reversing evolution of cod
(via sciencedaily.com) Intense fishing and over-exploitation have led to evolutionary changes in fish stocks like cod, reducing both their productivity and value on the market. These changes can be reversed by more sustainable and far-sighted fisheries management. A new study shows that reversal of evolutionary change would only slightly reduce the profit of fishing, but would help regain and conserve natural genetic diversity.
Published Humans are altering the diet of Tasmanian devils, which may accelerate their decline
(via sciencedaily.com) New research shows how human-modified landscapes affect the diets of these marsupial scavengers.
Published Humans bite back by deactivating mosquito sperm
(via sciencedaily.com) New research makes it likely that proteins responsible for activating mosquito sperm can be shut down, preventing them from swimming to or fertilizing eggs.
Published Compressive stress shapes the symmetry of Arabidopsis root vascular tissue
(via sciencedaily.com) A cytokinin-mediated, proliferation-based mechanism is involved in the generation and maintenance of cell-type specific tissue boundaries during vascular development in Arabidopsis roots. Specifically, the HANABA-TARANU transcription factor forms a feed-forward loop to cytokinin signaling, which in turn regulates the position and frequency of cell proliferation of proto-vascular cells such that mechanical stress of the surrounding tissues guides growth in an apical-oriented manor, maintaining cell patterning throughout the tissue section.
Published Where the HI-Virus sleeps in the brain
(via sciencedaily.com) The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent infections. The role of the structure and organization of the host genome in HIV-1 infection is not well understood. Using a cell culture model based on brain immune microglia cells, an international research team has now defined the insertion patterns of HIV-1 in the genome of microglia cells.
Published Cellular waste removal differs according to cell type
(via sciencedaily.com) 'Miniature shredders' are at work in each cell, disassembling and recycling cell components that are defective or no longer required. The exact structure of these shredders differs from cell type to cell type, a study now shows. For example, cancer cells have a special variant that can supply them particularly effectively with building blocks for their energy metabolism.
Published Study describes the structural and functional effects of several mutations on the androgen receptor
(via sciencedaily.com) The androgen receptor is a key transcriptional factor for the proper sex development -- especially in males -- and the physiological balance of all the tissues that express this receptor. The androgen receptor is involved in several pathologies and syndromes, such as the spinal and bulbar muscular atrophy or androgen insensitivity syndrome, among others, for which there is no specific treatment. Regarded as the main initial and progression factor in prostate cancer -- the second most common malignant disease in men in industrialized countries -- this receptor has been, for decades, the main therapeutical target for the treatment against this disease.
Published Genetics as conservation tool for endangered chimpanzees
(via sciencedaily.com) The western chimpanzees of Guinea are threatened by mining activities. Using a novel genetic approach, researchers have collected information on population size and community structure of the endangered species. These data provide an important baseline to assess the impact of mining.
Published Researchers highlight nucleolar DNA damage response in fight against cancer
(via sciencedaily.com) Researchers have now encapsulated the young field of nucleolar DNA damage response (DDR) pathways. A new review highlights six mechanisms by which cells repair DNA damage. By attacking these mechanisms, future applied researchers will be able to trip up cancer's reproduction and growth.
Published Making sense of scents: Deciphering our sense of smell
(via sciencedaily.com) Breaking a longstanding impasse in our understanding of olfaction, scientists have created the first molecular-level, 3D picture of how an odor molecule activates a human odorant receptor, a crucial step in deciphering the sense of smell.
Published Scientists discover key information about the function of mitochondria in cancer cells
(via sciencedaily.com) A new study represents a first step towards generating highly detailed 3-dimensional maps of lung tumors using genetically engineered mouse models.
Published Recovering tropical forests offset just one quarter of carbon emissions from new tropical deforestation and forest degradation
(via sciencedaily.com) A pioneering global study has found deforestation and forests lost or damaged due to human and environmental change, such as fire and logging, are fast outstripping current rates of forest regrowth.
Published Designing more useful bacteria
(via sciencedaily.com) In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.
Published 'Glow-in-the-dark' proteins could help diagnose viral diseases
(via sciencedaily.com) Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources. But now, a team has developed a sensitive method that analyzes viral nucleic acids in as little as 20 minutes and can be completed in one step with 'glow-in-the-dark' proteins.