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Categories: Biology: Molecular, Environmental: Biodiversity
Published New ways to study spinal cord malformations in embryos



Scientists have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida.
Published A better way to make RNA drugs



RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published Unprecedented warming threatens Earth's lakes and their ecosystems



Lakes, with their rich biodiversity and important ecological services, face a concerning trend: rapidly increasing temperatures. A recent study by limnologists and climate modelers reveals that if current anthropogenic warming continues until the end of this century, lakes worldwide will likely experience pervasive and unprecedented surface and subsurface warming, far outside the range of what they have encountered before.
Published Muscle machine: How water controls the speed of muscle contraction



The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study.
Published Nanoplastics and 'forever chemicals' disrupt molecular structures, functionality



Researchers have made significant inroads in understanding how nanoplastics and per- and polyfluoroalkyl substances (PFAS) -- commonly known as forever chemicals -- disrupt biomolecular structure and function. The work shows that the compounds can alter proteins found in human breast milk and infant formulas -- potentially causing developmental issues downstream.
Published Mapping the world's fungi from air samples



Researchers have found that the key to a quick and cost-effective mapping of biodiversity has been right in front of our eyes all along, but at the same time invisible -- i.e., in the air that surrounds us.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed



International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin



An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published Atlas of proteins reveals inner workings of cells



Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.
Published Big gain in battle against harmful bacteria



An unexpected find has enabled important progress to be made in the battle against harmful bacteria.
Published New one-step method to make multiple edits to a cell's genome



A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.
Published Global database reveals large gaps in our knowledge of four-footed animals



Researchers developed TetrapodTraits -- a global database of animals with four feet -- which can now be applied for better ecology, evolution and conservation research.
Published First local extinction in the US due to sea level rise, study suggests



The United States has lost its only stand of the massive Key Largo tree cactus in what researchers believe is the first local extinction of a species caused by sea level rise in the country.
Published Study reveals environmental impact of artificial sweeteners



A recently published study demonstrates how sucralose affects the behavior of cyanobacteria -- an aquatic photosynthetic bacteria -- and diatoms, microscopic algae that account for more than 30% of the primary food production in the marine food chain.
Published Restored oyster sanctuaries host more marine life



Oysters sanctuaries in Chesapeake Bay are working for more than just oysters. Compared to nearby harvest areas, sanctuaries contain more abundant populations of oysters and other animal life--and the presence of two common parasites isn't preventing that.
Published New bio-based tool quickly detects concerning coronavirus variants



Researchers have developed a bioelectric device that can detect and classify new variants of coronavirus to identify those that are most harmful. It has the potential to do the same with other viruses, as well.
Published GeneMAP discovery platform will help define functions for 'orphan' metabolic proteins



Researchers have developed a discovery platform to probe the function of genes involved in metabolism -- the sum of all life-sustaining chemical reactions. The investigators used the new platform, called GeneMAP (Gene-Metabolite Association Prediction), to identify a gene necessary for mitochondrial choline transport.
Published Why the U.S. food system needs agroecology



Agroecology -- a science, practice, and movement which seeks social, political, economic, and environmental sustainability in the global food system -- is gaining momentum in the U.S., according to a new article.
Published Never-before-seen view of gene transcription captured



New tech reveals findings that address long-standing theories about how bacteria begin the process of making RNA from DNA.
Published Do genes-in-pieces code for proteins that fold in pieces?



A new study offers new insights into the evolution of foldable proteins.