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Categories: Biology: Molecular, Environmental: Biodiversity
Published Researchers discover how we perceive bitter taste
(via sciencedaily.com) Original source A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.
Published A new coating method in mRNA engineering points the way to advanced therapies
(via sciencedaily.com) Original source Researchers have developed a novel method of adding polyethylene glycol molecules to engineered groups of messenger RNAs called 'mRNA polyplexes', which enable the cells that receive them to produce specific proteins. This technique allows greater control of the site in the body to which the polyplexes are delivered, significantly advancing the field of therapeutic mRNA technologies, with applications in vaccine development and the treatment of cancer and other diseases.
Published Cockayne syndrome: New insights into cellular DNA repair mechanism
(via sciencedaily.com) Original source Researchers decode repair mechanism during transcription of genetic information.
Published Deforestation harms biodiversity of the Amazon's perfume-loving orchid bees
(via sciencedaily.com) Original source A survey of orchid bees in the Brazilian Amazon, carried out in the 1990s, is shedding new light the impact of deforestation on the scent-collecting pollinators, which some view as bellwethers of biodiversity in the neotropics.
Published 'Teacher Toads' can save native animals from toxic cane toads
(via sciencedaily.com) Original source Scientists from Macquarie University have come up with an innovative way to stop cane toads killing native wildlife by training goannas to avoid eating the deadly amphibians.
Published Humans can increase biodiversity, archaeological study shows
(via sciencedaily.com) Original source Through the ages, the presence of humans has increased the heterogeneity and complexity of ecosystems and has often had a positive effect on their biodiversity.
Published Machine learning method reveals chromosome locations in individual cell nucleus
(via sciencedaily.com) Original source Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.
Published Different means to the same end: How a worm protects its chromosomes
(via sciencedaily.com) Original source Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.
Published Boreal forest and tundra regions worst hit over next 500 years of climate change, study shows
(via sciencedaily.com) Original source Modelling climate change over a 500 year period shows that much of the boreal forest, the Earth's northernmost forests and most significant provider of carbon storage and clean water, could be seriously impacted, along with tundra regions, treeless shrublands north of the boreal forest that play a significant role in regulating the Earth's climate.
Published Bringing multidrug-resistant pathogens to their knees
(via sciencedaily.com) Original source Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.
Published Can language models read the genome? This one decoded mRNA to make better vaccines
(via sciencedaily.com) Original source Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.
Published Four in five bird species cannot tolerate intense human pressures
(via sciencedaily.com) Original source In a recent study, researchers found that 78% of the world's bird species do not thrive in the most modified human-dominated environments. These species are also most likely to have declining populations.
Published The life aquatic: A game changer for frog vision, but little difference between night and day
(via sciencedaily.com) Original source Frogs display a remarkable diversity of species as a whole, but does the same hold true for their visual abilities? A new study sought to answer this question by collaborating with researchers in Australia, Belgium, Brazil, Cameroon, Ecuador, Equatorial Guinea, French Guiana, Gabon, Seychelles, Sweden, United Kingdom and the United States, to get a sample of a diverse array of frogs to study the visual pigments found in their eyes. The researchers found this diversity is largely 'reflected' in the pigments, especially for aquatic frogs versus those living on the ground or in trees. They found little difference with the small groups of frogs that have adapted to daytime conditions as opposed to their nocturnal cousins.
Published Adult fish struggle to bounce back in marine protected areas
(via sciencedaily.com) Original source Many marine protected areas are falling short of their most basic purpose: to rebuild struggling fish populations. In a new study, scientists looked at the age breakdown of reef fish in marine protected areas for the first time. They discovered in almost all of them, adult fish populations -- vital to spawning the next generation -- have either flatlined or declined.
Published With the planet facing a 'polycrisis', biodiversity researchers uncover major knowledge gaps
(via sciencedaily.com) Original source Connecting the study of infectious disease spread, biodiversity loss and climate change could offer win-win-win solutions for planetary health, but a new analysis has uncovered almost no research integrating the three global crises.
Published Heat flows the secret to order in prebiotic molecular kitchen
(via sciencedaily.com) Original source Biophysicists have demonstrated how heat flows through rock fissures could have created the conditions for the emergence of life.
Published New tools reveal how genes work and cells organize
(via sciencedaily.com) Original source Researchers have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have developed computational tools capable of predicting these protein-RNA interactions. The newfound ability to predict these interactions can help future work in understanding molecular pathways in the cell and pave the way for developing drugs targeting these RNA G-quadruplex binding proteins, that are found to be involved in disease such as cancer.
Published Evolution in action? New study finds possibility of nitrogen-fixing organelles
(via sciencedaily.com) Original source A new study finds that UCYN-A, a species of nitrogen-fixing cyanobacteria, may be evolving organelle-like characteristics.
Published Demand for critical minerals puts African Great Apes at risk
(via sciencedaily.com) Original source A recent study shows that the threat of mining to the great ape population in Africa has been greatly underestimated.
Published New discovery unravels malaria invasion mechanism
(via sciencedaily.com) Original source A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study reveals the role of a sugar called sialic acid in this invasion process. The findings have major implications for malaria vaccine and drug development.