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Categories: Biology: Molecular, Environmental: Biodiversity

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     (via sciencedaily.com)     Original source 

In a world where the intricacies of molecular biology often seem as vast and mysterious as the cosmos, a new groundbreaking study delves into the microscopic universe of proteins, unveiling a fascinating aspect of their existence. This revelation could hold profound implications for the understanding and treatment of a myriad of human diseases.

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An online survey conducted in Germany and Poland shows that large parts of the participants support the return of large carnivores and herbivores, such as wolves and elk, to the Oder Delta region. Presented with different rewilding scenarios, the majority of survey participants showed a preference for land management that leads to the comeback of nature to the most natural state possible. Locals, on the other hand, showed some reservations.

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By tightly regulating nitrogen uptake, microorganisms avoid overeating nitrogen and thus wasting energy. Scientists now reveal how some methanogenic archaea manage to do so.

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You suddenly feel sick -- pathogenic bacteria have managed to colonize and spread in your body! The weapons they use for their invasion are harmful toxins that target the host's defense mechanisms and vital cell functions. Before these deadly toxins can attack host cells, bacteria must first export them from their production site -- the cytoplasm -- using dedicated secretion systems.

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The collaboration between scientists, farmers and managers is crucial to improve the protection of the little bustard, an endangered steppe-land bird in Spain due to human activity. The reduction of natural habitats, the increase in irrigation and the urbanization of the land have led to having less surface areas that guarantee the survival of this vulnerable species.

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Protecting the world ocean against accelerating damage from human activities could be cheaper and take up less space than previously thought, new research has found.

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Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.

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The cell nucleus is considered to be the control center of vital cellular processes, but its material properties continue to puzzle scientists. An international research team has now developed a new technique that provides a previously unattainable view of the mechanical properties inside this control center. For the first time, it has been possible to visualize over time its peculiar dynamic structural features in living cells, which appear to be crucial for cell function.

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Southern Africa contains the vast majority of the world's remaining populations of both black and white rhinoceroses (80% and 92%, respectively). The region's climate is changing rapidly as a result global warming. Traditional conservation efforts aimed at protecting rhinos have focused on poaching, but until now, there has been no analysis of the impact that climate change may have on the animals. A research team has recently reported that, though the area will be affected by both higher temperatures and changing precipitation, the rhinos are more sensitive to rising temperatures, which will quickly increase above the animals' acceptable maximum threshold.

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Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.

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To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.

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A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.

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Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.

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Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.

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To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.

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Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.

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In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.

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A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.

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Research has determined key factors that impact biodiversity among spiders and insects in urban areas. The response of specific groups varied significantly, surprising the researchers. The study findings can help urban planners, landscapers, builders and homeowners make choices that increase biodiversity. Dozens of species previously unknown to science came to light through the study.

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Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.