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Categories: Biology: Molecular, Environmental: Biodiversity

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A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.

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Researchers have discovered a molecular 'barcode' system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.

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Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane. Like a forklift, a soluble protein outside the bacterium transports the substance to the 'elevator' and unloads its cargo there. The freight elevator transports it to the inside of the cell, in other words to another floor.

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Frequent visits to oil palm plantations are leading to a sharp increase in mortality rates among infant southern pig-tailed macaques (Macaca nemestrina) in the wild, according to a new study. In addition to increased risk from predators and human encounters, exposure to harmful agricultural chemicals in this environment may negatively affect infant development.

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The largest analysis yet of African savannah elephant populations shows that conservationists have successfully protected elephants in southern Africa for the last 25 years. However, the pattern varies regionally, with some elephant populations soaring and others still facing large declines. The key to long-term stability appears to be connecting large core areas with neighboring buffer zones, as opposed to well-protected but isolated protected areas known as 'fortress conservation.'

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In a recent tragic incident, approximately 100 elephants in Africa perished due to inadequate access to water. The United Nations Environment Programme (UNEP) issues a warning that around 2.5 billion people worldwide could face water scarcity by 2025. In the face of water shortages affecting not only human society but also the entire ecological community due to the climate crisis, it becomes crucial to adopt comprehensive measures for managing water quality and quantity to avert such pressing challenges.

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Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins -- and ultimately affect aging.

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New research shows that some groups of bacteria in the gut are amazingly resourceful, with a large repertoire of genes that help them generate energy for themselves and potentially influence human health as well.

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A decades-old mystery of how natural antimicrobial predatory bacteria are able to recognize and kill other bacteria may have been solved, according to new research.

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Biologists developed a method for illuminating the intricate interactions of the synaptonemal complex in the nematode C. elegans. The authors identified a trio of protein segments that guide chromosomal interactions, and pinpointed the location where they interact with each other. Their novel method uses a technique known as genetic suppressor screening, which can serve as a blueprint for research on large cellular assemblies that resist traditional structural analysis.

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Researchers have determined how Eastern equine encephalitis virus attaches to a receptor it uses to enter and infect cells. The findings laid the groundwork for a receptor decoy molecule that protects mice from encephalitis caused by the virus.

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Many bacterial pathogens use small injection apparatuses to manipulate the cells of their hosts, such as humans, so that they can spread throughout the body. To do this, they need to fill their syringes with the relevant injection agent. A technique that tracks the individual movement of proteins revealed how bacteria accomplish this challenging task.

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A new study to motivate your New Year's resolutions: it demonstrates that high-fat diets negatively impact genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system and brain function.

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Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning.

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Three modules forming a new-to-nature CO2 fixation cycle have been successfully implemented in E.coli.

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Tiny things matter -- for instance, one amino acid can completely alter the architecture of the cell. Researchers have now investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin. Actin is found in all living cells where it has a range of important functions -- from muscle contraction to cell signalling and cell shape. This protein comes in two different varieties termed 'isoforms', which are known as gamma actin and beta actin.

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At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -- but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage. Jellyfish, along with other cnidarians such as corals and sea anemones, exhibit high regeneration abilities, but how they form the critical blastema has remained a mystery until now.

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A lot has changed in the world since the Endangered Species Act (ESA) was enacted 50 years ago in December 1973. Experts are now discuss how the ESA has evolved and what its future might hold. 

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Scientists reveal how G protein-coupled receptors, major therapeutic drug targets, decode critical properties of their ligands.

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A new study identifies five new species of soft-furred hedgehogs from Southeast Asia. The study used DNA analysis and physical characteristics to describe two entirely new species of soft-furred hedgehogs and elevate three subspecies to the level of species.