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Categories: Biology: Molecular, Environmental: Biodiversity
Published Scientists take major step towards completing the world's first synthetic yeast
(via sciencedaily.com) Original source A team of Scientists has completed construction of a synthetic chromosome as part of a major international project to build the world's first synthetic yeast genome. The work represents completion of one of the 16 chromosomes of the yeast genome, which is part of the biggest project ever in synthetic biology; the international synthetic yeast genome collaboration. The collaboration, known as 'Sc2.0' has been a 15-year project involving teams from around the world (UK, US, China, Singapore, UK, France and Australia), working together to make synthetic versions of all of yeast's chromosomes. Alongside this paper, another 9 publications are also released today from other teams describing their synthetic chromosomes. The final completion of the genome project -- the largest synthetic genome ever -- is expected next year.
Published Obesity linked to neurodegeneration through insulin resistance
(via sciencedaily.com) Original source Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.
Published 'Biodiversity time machine' provides insights into a century of loss
(via sciencedaily.com) Original source AI analysis shows pollution levels, extreme weather events and increasing temperatures devastates biodiversity in freshwater lakes.
Published New algae species rewrites understanding of reef systems
(via sciencedaily.com) Original source An international team of marine scientists has identified and officially named four species of algae new to science, challenging previous taxonomical assumptions within the Porolithon genus. The discovery has far-reaching implications for our understanding of the ecological role of these algae in the coral reef ecosystem.
Published Threatened sharks and rays caught off Cyprus
(via sciencedaily.com) Original source Sharks and rays from threatened species are being caught off northern Cyprus, according to a new study by scientists who are working with local authorities and fishers to protect the animals.
Published Some benefits of exercise stem from the immune system
(via sciencedaily.com) Original source Research in mice shows that the anti-inflammatory properties of exercise may arise from immune cells mobilized to counter exercise-induced inflammation. Immune cells prevent muscle damage by lowering levels of interferon, a key driver of chronic inflammation, inflammatory diseases, and aging.
Published Large herbivores such as elephants, bison and moose contribute to tree diversity
(via sciencedaily.com) Original source Using global satellite data, a research team has mapped the tree cover of the world's protected areas. The study shows that regions with abundant large herbivores in many settings have a more variable tree cover, which is expected to benefit biodiversity overall.
Published New antibiotic approach proves promising against lyme bacterium
(via sciencedaily.com) Original source Using a technique that has shown promise in targeting cancer tumors, a team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease.
Published Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence
(via sciencedaily.com) Original source Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.
Published Female sex determining gene identified in mice
(via sciencedaily.com) Original source Researchers have identified a gene which is an early determining factor of ovary development in mice.
Published A known environmental hazard can change the epigenetics of cells
(via sciencedaily.com) Original source An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.
Published Research connecting gut bacteria and oxytocin provides a new mechanism for microbiome-promoted health benefits
(via sciencedaily.com) Original source Researchers found that the hormone oxytocin, known to be involved in regulating feeding and social behavior and until now to be produced mostly in the brain, is also produced in the human intestine. Furthermore, gut resident bacteria L. reuteri can affect the production of gut-made oxytocin, providing the first insights into a mechanism by which these bacteria can influence human health.
Published Immunology: Dysfunction of mitochondria drives the exhaustion of T cells
(via sciencedaily.com) Original source In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells
(via sciencedaily.com) Original source Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published Buzz around new centralized pollination portal for better global bee data
(via sciencedaily.com) Original source A powerful new way to fill major gaps in public bee data -- including from Africa, Asia and other under-reported zones -- has been addressed with a centralized tool for consolidating bee pollinator occurrences around the globe.
Published First mice engineered to survive COVID-19 like young, healthy humans
(via sciencedaily.com) Original source Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published Plastic-eating bacteria turn waste into useful starting materials for other products
(via sciencedaily.com) Original source Mountains of used plastic bottles get thrown away every day, but microbes could potentially tackle this problem. Now, researchers report that they've developed a plastic-eating E. coli that can efficiently turn polyethylene terephthalate (PET) waste into adipic acid, which is used to make nylon materials, drugs and fragrances.
Published New map of 20th century land use in Britain helps researchers demystify biodiversity change
(via sciencedaily.com) Original source Researchers have mapped how land use changed across Britain throughout the last century. The new map reveals how and where some 50 per cent of semi-natural grassland was lost, including 90 per cent of the country's lowland meadows and pasture, as the nation intensified its agriculture.
Published Australasia's hidden pollination crisis could threaten biodiversity and food security
(via sciencedaily.com) Original source Australasia's hidden pollination crisis, mirroring global threats, could pose a significant risk to regional biodiversity and food security, new research has found.
Published Amazon deforestation linked to long distance climate warming
(via sciencedaily.com) Original source Deforestation in the Amazon causes land surfaces up to 100 kilometers away to get warmer, suggests a new study. The research suggests that tropical forests play a critical role in cooling the land surface -- and that effect can play out over considerable distances.