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Categories: Biology: Molecular, Space: The Solar System

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Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

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What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.

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Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.

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Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.

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A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.

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Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.

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It looks like a black hole and bends light like a black hole, but it could actually be a new type of star. Though the mysterious object is a hypothetical mathematical construction, new simulations by Johns Hopkins researchers suggest there could be other celestial bodies in space hiding from even the best telescopes on Earth.

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A star's chemical composition strongly influences the ultraviolet radiation it emits into space and thus the conditions for the emergence of life in its neighborhood.

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Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail. This technology has potential uses in tissue engineering, regenerative medicine, and understanding how the body works. The scientists applied their new method to control the glow of a green fluorescent protein derived from Japanese eel muscle.

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A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings. A study now shows how two molecular mechanisms can work together make the bacterium extra resistant.

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Research has traced the evolutionary adaptations of octopus and squid sensing capabilities. The researchers describe for the first time the structure of an octopus chemotactile receptor, which octopus arms use for taste-by-touch exploration of the seafloor.

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An international team of astronomers announced the first exoplanet discovered through a combined approach of direct imaging and precision measurements of a star's motion on the sky. This new method promises to improve the efficiency of exoplanet searches, paving the way for the discovery of an Earth twin.

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Researchers describe how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body's ability to suppress it.

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Astronomers report the first exoplanet jointly discovered through direct imaging and precision astrometry, a new indirect method that identifies a planet by measuring the position of the star it orbits. Data from the Subaru Telescope in Hawai`i and space telescopes from the European Space Agency (ESA) were integral to the team's discovery.

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Origin-of-life chemists propose that glyoxylate could have been the original source of sugars on the 'prebiotic' Earth

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From Earth, giant elliptical galaxies resemble highly symmetric blobs, but what's their real 3D structure? Astronomers have assembled one of the first 3D views of a giant elliptical galaxy, M87, whose central supermassive black hole has already been imaged by the Event Horizon Telescope. M87 turns out to be triaxial, like a potato. The revised view provides a more precise measure of the mass of the central black hole: 5.37 billion solar masses.

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A research team has recently made a significant discovery about the evolutionary age of different type of cells in a small animal called Caenorhabditis elegans (C. elegans). By using single-cell transcriptomic data and refined phylostratigraphy, the team determines the transcriptomic age of individual cells, which means they are able to estimate the evolutionary origin of different cells based on the age of the genes expressed in the cells.

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In a series of experiments, a team of researchers have compared de novo proteins with random-sequence proteins, looking at their stability and solubility. The results are set to advance basic research in this new field.

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Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.

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Our planet's water could have originated from interactions between the hydrogen-rich atmospheres and magma oceans of the planetary embryos that comprised Earth's formative years.