Showing 20 articles starting at article 1121
< Previous 20 articles Next 20 articles >
Categories: Biology: Molecular, Space: The Solar System
Published Humans bite back by deactivating mosquito sperm
(via sciencedaily.com) New research makes it likely that proteins responsible for activating mosquito sperm can be shut down, preventing them from swimming to or fertilizing eggs.
Published Compressive stress shapes the symmetry of Arabidopsis root vascular tissue
(via sciencedaily.com) A cytokinin-mediated, proliferation-based mechanism is involved in the generation and maintenance of cell-type specific tissue boundaries during vascular development in Arabidopsis roots. Specifically, the HANABA-TARANU transcription factor forms a feed-forward loop to cytokinin signaling, which in turn regulates the position and frequency of cell proliferation of proto-vascular cells such that mechanical stress of the surrounding tissues guides growth in an apical-oriented manor, maintaining cell patterning throughout the tissue section.
Published Where the HI-Virus sleeps in the brain
(via sciencedaily.com) The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent infections. The role of the structure and organization of the host genome in HIV-1 infection is not well understood. Using a cell culture model based on brain immune microglia cells, an international research team has now defined the insertion patterns of HIV-1 in the genome of microglia cells.
Published Cellular waste removal differs according to cell type
(via sciencedaily.com) 'Miniature shredders' are at work in each cell, disassembling and recycling cell components that are defective or no longer required. The exact structure of these shredders differs from cell type to cell type, a study now shows. For example, cancer cells have a special variant that can supply them particularly effectively with building blocks for their energy metabolism.
Published Study describes the structural and functional effects of several mutations on the androgen receptor
(via sciencedaily.com) The androgen receptor is a key transcriptional factor for the proper sex development -- especially in males -- and the physiological balance of all the tissues that express this receptor. The androgen receptor is involved in several pathologies and syndromes, such as the spinal and bulbar muscular atrophy or androgen insensitivity syndrome, among others, for which there is no specific treatment. Regarded as the main initial and progression factor in prostate cancer -- the second most common malignant disease in men in industrialized countries -- this receptor has been, for decades, the main therapeutical target for the treatment against this disease.
Published Researchers highlight nucleolar DNA damage response in fight against cancer
(via sciencedaily.com) Researchers have now encapsulated the young field of nucleolar DNA damage response (DDR) pathways. A new review highlights six mechanisms by which cells repair DNA damage. By attacking these mechanisms, future applied researchers will be able to trip up cancer's reproduction and growth.
Published Evidence that Venus is volcanically active
(via sciencedaily.com) Venus appears to have volcanic activity, according to a new research paper that offers strong evidence to answer the lingering question about whether Earth's sister planet currently has eruptions and lava flows.
Published Remains of a modern glacier found near Mars' equator implies water ice possibly present at low latitudes on Mars even today
(via sciencedaily.com) Scientists revealed the discovery of a relict glacier near Mars' equator. Located in Eastern Noctis Labyrinthus at coordinates 7° 33' S, 93° 14' W, this finding is significant as it implies the presence of surface water ice on Mars in recent times, even near the equator. This discovery raises the possibility that ice may still exist at shallow depths in the area, which could have significant implications for future human exploration.
Published Where did Earth's water come from? Not melted meteorites, according to scientists
(via sciencedaily.com) A new study brings scientists one step closer to answering the question of where Earth's water came from.
Published Making sense of scents: Deciphering our sense of smell
(via sciencedaily.com) Breaking a longstanding impasse in our understanding of olfaction, scientists have created the first molecular-level, 3D picture of how an odor molecule activates a human odorant receptor, a crucial step in deciphering the sense of smell.
Published Scientists discover key information about the function of mitochondria in cancer cells
(via sciencedaily.com) A new study represents a first step towards generating highly detailed 3-dimensional maps of lung tumors using genetically engineered mouse models.
Published Designing more useful bacteria
(via sciencedaily.com) In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.
Published 'Glow-in-the-dark' proteins could help diagnose viral diseases
(via sciencedaily.com) Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources. But now, a team has developed a sensitive method that analyzes viral nucleic acids in as little as 20 minutes and can be completed in one step with 'glow-in-the-dark' proteins.
Published Molecular component of caffeine may play a role in gut health
(via sciencedaily.com) A new study explores exactly what leads to the generation of Th17 cells -- an important subtype of cells in the intestine -- and uncovers some of the underappreciated molecular players and events that lead to cell differentiation in the gut.
Published Mirror-image molecules can modify signaling in neurons
(via sciencedaily.com) With the aid of some sea slugs, chemists have discovered that one of the smallest conceivable tweaks to a biomolecule can elicit one of the grandest conceivable consequences: directing the activation of neurons. The team has shown that the orientation of a single amino acid -- in this case, one of dozens found in the neuropeptide of a sea slug -- can dictate the likelihood that the peptide activates one neuron receptor versus another. Because different types of receptors are responsible for different neuronal activities, the finding points to another means by which a brain or nervous system can regulate the labyrinthine, life-sustaining communication among its cells.
Published Researchers develop enhanced genetic animal model of Down syndrome
(via sciencedaily.com) Original source Researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced. The new mouse model shows milder cognitive traits compared to a previously studied Down syndrome mouse model.
Published Biological network in cells helps body adapt to stresses on health
(via sciencedaily.com) Scientists have done research that opens up a whole new world within our cells. Their study uncovers a vast network of interactions that assist cells in adjusting in real time to withstand stresses on our health.
Published TurboID uncovers new meiotic proteins in Arabidopsis thaliana
(via sciencedaily.com) Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis which is critical for meiotic recombination and genetically diverse gametes. An international research team reports the application of a TurboID (TbID)-based approach to identify proteins in proximity of meiotic chromosome axes in Arabidopsis thaliana. Not only known but also new meiotic proteins were uncovered.
Published A quick new way to screen virus proteins for antibiotic properties
(via sciencedaily.com) A whole new world of antibiotics is waiting inside the viruses that infect bacteria. Scientists are making it easier to study them.
Published Triggering bitter taste receptors could someday treat asthma, COPD
(via sciencedaily.com) Surprisingly, bitter taste receptors are not only located in the mouth, but also elsewhere in the body, including the airways. Activating those receptors opens up lung passageways, so they're a potential target for treating asthma or chronic obstructive pulmonary disease (COPD). Now, researchers report that they have designed a potent and selective compound that could lead the way to such therapies.