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Categories: Biology: Molecular, Space: The Solar System
Published Machine learning reveals sources of heterogeneity among cells in our bodies
(via sciencedaily.com) Original source A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Glowing COVID-19 diagnostic test prototype produces results in one minute
(via sciencedaily.com) Original source Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.
Published Space solar power project ends first in-space mission with successes and lessons
(via sciencedaily.com) Original source A 10-month mission demonstrated three elements of the plan to beam solar power from space to Earth.
Published Unraveling the role of supersulfides in regulating mitochondrial function and longevity
(via sciencedaily.com) Original source Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.
Published Discovery changes understanding of water's history on the Moon
(via sciencedaily.com) Original source New research shows the early lunar crust which makes up the surface of the Moon was considerably enriched in water more than 4 billion years ago, counter to previously held understanding.
Published Research sheds new light on Moon rock formation solving major puzzle in lunar geology
(via sciencedaily.com) Original source New research has cracked a vital process in the creation of a unique rock type from the Moon. The discovery explains its signature composition and very presence on the lunar surface at all, unraveling a mystery which has long-eluded scientists.
Published Earth-sized planet discovered in 'our solar backyard'
(via sciencedaily.com) Original source Astronomers have discovered a planet closer and younger than any other Earth-sized world yet identified. It's a remarkably hot world whose proximity to our own planet and to a star like our sun mark it as a unique opportunity to study how planets evolve.
Published Bioinformatics: Researchers develop a new machine learning approach
(via sciencedaily.com) Original source To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published A novel pathway regulating lipid biosynthesis by fatty acids
(via sciencedaily.com) Original source Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published New insights into what helps Salmonella cause infections
(via sciencedaily.com) Original source In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening
(via sciencedaily.com) Original source A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging
(via sciencedaily.com) Original source Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published Spying on a shape-shifting protein
(via sciencedaily.com) Original source Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published Study uncovers potential origins of life in ancient hot springs
(via sciencedaily.com) Original source A research team investigated how the emergence of the first living systems from inert geological materials happened on the Earth, more than 3.5 billion years ago. Scientists found that by mixing hydrogen, bicarbonate, and iron-rich magnetite under conditions mimicking relatively mild hydrothermal vent results in the formation of a spectrum of organic molecules, most notably including fatty acids stretching up to 18 carbon atoms in length.
Published Even the oldest eukaryote fossils show dazzling diversity and complexity
(via sciencedaily.com) Original source The sun has just set on a quiet mudflat in Australia's Northern Territory; it'll set again in another 19 hours. A young moon looms large over the desolate landscape. No animals scurry in the waning light. No leaves rustle in the breeze. No lichens encrust the exposed rock. The only hint of life is some scum in a few puddles and ponds. And among it lives a diverse microbial community of our ancient ancestors.
Published Our surprising magnetic galaxy
(via sciencedaily.com) Original source A team of astronomers has created the first-ever map of magnetic field structures within a spiral arm of our Milky Way galaxy. Previous studies on galactic magnetic fields only gave a very general picture, but the new study reveals that magnetic fields in the spiral arms of our galaxy break away from this general picture significantly and are tilted away from the galactic average by a high degree. The findings suggest magnetic fields strongly impact star-forming regions which means they played a part in the creation of our own solar system.
Published Lab-grown retinas explain why people see colors dogs can't
(via sciencedaily.com) Original source With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.
Published Protein complex discovered to control DNA repair
(via sciencedaily.com) Original source The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published Astronomers make rare exoplanet discovery, and a giant leap in detecting Earth-like bodies
(via sciencedaily.com) Original source Astronomers have made the rare discovery of a small, cold exoplanet and its massive outer companion -- shedding light on the formation of planets like Earth.
Published Potential solvents identified for building on moon and Mars
(via sciencedaily.com) Original source Researchers have taken the first steps toward finding liquid solvents that may someday help extract critical building materials from lunar and Martian-rock dust, an important piece in making long-term space travel possible. Using machine learning and computational modeling, researchers have found about half a dozen good candidates for solvents that can extract materials on the moon and Mars usable in 3D printing. The powerful solvents, called ionic liquids, are salts that are in a liquid state.