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Categories: Biology: Molecular, Space: The Solar System
Published Fetal brain impacted when mom fights severe flu: New mouse study explains how



New research using live mouse-adapted influenza virus improves upon previous mouse experiments to explain how maternal infection impacts fetal brain development. The study also indicates fetal brain changes are more likely once the severity of the mother's infection meets a specific threshold.
Published Researchers decipher new molecular mechanisms related to biological tissue regeneration



A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease and several types of cancer.
Published Lampreys possess a 'jaw-dropping' evolutionary origin



Lampreys are one of only two living jawless vertebrates Jaws are formed by a key stem cell population called the neural crest New research reveals the gene regulatory changes that may explain morphological differences between jawed and jawless vertebrates.
Published New drug shows promise in clearing HIV from brain



An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.
Published Space-trekking muscle tests drugs for microgravity-induced muscle impairment



A gentle rumble ran under a researcher's feet as a rocket carrying her research -- live, human muscle cells grown on scaffolds fixed on tiny chips -- lifted off, climbed, and disappeared into the sky to the International Space Station National Laboratory. These chips would help her better understand muscle impairment, often seen in astronauts and older adults, and test drugs to counter the condition.
Published Research sheds light on the role of PTPRK in tissue repair and cancer



New research has advanced our knowledge of multiple roles for PTPRK, a receptor tyrosine phosphatase linked to the regulation of cell-cell adhesion, growth factor signalling and tumor suppression. Through a characterization of the function of PTPRK in human cell lines and mice, the team distinguished catalytic and non-catalytic functions of PTPRK. The findings extend what is known about the signalling mechanisms involving PTPRK as a phosphatase and its role in colorectal health but also shed new light on the extent of its function via non-catalytic signalling mechanisms.
Published Images of nearest 'super-Jupiter' open a new window to exoplanet research



Using the James Webb Space Telescope (JWST), astronomers imaged a new exoplanet that orbits a star in the nearby triple system Epsilon Indi. The planet is a cold super-Jupiter exhibiting a temperature of around 0 degrees Celsius and a wide orbit comparable to that of Neptune around the Sun. This measurement was only possible thanks to JWST's unprecedented imaging capabilities in the thermal infrared. It exemplifies the potential of finding many more such planets similar to Jupiter in mass, temperature, and orbit. Studying them will improve our knowledge of how gas giants form and evolve in time.
Published Under pressure: How cells respond to physical stress



Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists have used cryo-electron microscopy to observe how lipids and proteins at the plasma membrane interact and react to mechanical stress. This work shows that, depending on conditions, small membrane regions can stabilize various lipids to trigger specific cellular responses. These discoveries confirm the existence of well-organized lipid domains and begin to reveal the role they play in cell survival.
Published Dual action antibiotic could make bacterial resistance nearly impossible



New drug that disrupts two cellular targets would make it much harder for bacteria to evolve resistance.
Published New rapid method for determining virus infectivity



A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionize the response to future pandemics, researchers report.
Published Expiring medications could pose challenge on long space missions



A new study shows that over half of the medicines stocked in space -- staples such as pain relievers, antibiotics, allergy medicines, and sleep aids -- would expire before astronauts could return to Earth.
Published Fruit fly post-mating behavior controlled by male-derived peptide via command neurons, study finds



Scientists have succeeded in pinpointing the neurons within a female fruit fly's brain that respond to signals from the male during mating.
Published Researchers explore the effects of stellar magnetism on potential habitability of exoplanets



A study extends the definition of a habitable zone for planets to include their star's magnetic field.
Published Astrophysicists uncover supermassive blackhole/dark matter connection in solving the 'final parsec problem'



Researchers have found a link between some of the largest and smallest objects in the cosmos: supermassive black holes and dark matter particles. Their new calculations reveal that pairs of supermassive black holes (SMBHs) can merge into a single larger black hole because of previously overlooked behavior of dark matter particles, proposing a solution to the longstanding 'final parsec problem' in astronomy.
Published Exposing dengue's invasion strategies



Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease. Now, research uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts, with the potential to aid in developing novel antiviral treatments and vaccines.
Published Not everything that tastes bitter is potentially harmful: But why? Study provides an explanation



A bitter taste is traditionally considered a warning sign of potentially toxic substances. But not all bitter substances are harmful. For example, some peptides and free amino acids taste bitter, even though they are non-toxic, nutritious and sometimes even vital for humans. A new study now offers an explanation for this seemingly paradoxical phenomenon.
Published Transient structure in fly leg holds clue to insect shape formation



A little leg may reveal something big about how closely related insect species can drastically differ in body shape, according to a new study. The team imaged live cells of fruit flies in the last stages of development over several days and found a new structure that appears to help guide a section of the leg into its final shape.
Published Life signs could survive near surfaces of Enceladus and Europa



Europa and Enceladus, icy moons of Jupiter and Saturn respectively, have evidence of oceans beneath their crusts. A NASA experiment suggests -- if these oceans support life -- signatures of that life in the form of organic molecules (like amino acids and nucleic acids) could survive just under the surface ice despite the harsh, ionizing radiation on these worlds. If robotic landers were to go to these moons to look for life signs, they would not have to dig very deep to find amino acids that have survived being altered or destroyed by radiation.
Published Early riser! The Sun is already starting its next solar cycle -- despite being halfway through its current one



The first rumblings of the Sun's next 11-year solar cycle have been detected in sound waves inside our home star -- even though it is only halfway through its current one. This existing cycle is now at its peak, or 'solar maximum' -- which is when the Sun's magnetic field flips and its poles swap places -- until mid-2025.
Published New dawn for space storm alerts could help shield Earth's tech



Space storms could soon be forecasted with greater accuracy than ever before thanks to a big leap forward in our understanding of exactly when a violent solar eruption may hit Earth. Scientists say it is now possible to predict the precise speed a coronal mass ejection (CME) is travelling at and when it will smash into our planet -- even before it has fully erupted from the Sun.