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Categories: Biology: Molecular, Environmental: Water
Published Deadly sea snail toxin could be key to making better medicines
(via sciencedaily.com) Original source Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet.
Published Gut microbial pathway identified as target for improved heart disease treatment
(via sciencedaily.com) Original source Researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The study found phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.
Published Researchers develop index to quantify circular bioeconomy
(via sciencedaily.com) Original source As the world faces the challenges of mitigating climate change and providing resources for a growing population, there is increasing focus on developing circular economies for sustainable production. But to evaluate strategies and impacts, it is necessary to have reliable metrics. Researchers have now developed a Circularity Index that provides a comprehensive method to quantify circularity in bioeconomic systems. In a new paper, they outline the method and apply it to two case studies -- a corn/soybean farming operation and the entire U.S. food and agriculture system.
Published Forest loss intensifies climate change by increasing temperatures and cloud level, which leads to decrease of water
(via sciencedaily.com) Original source Researchers report that deforestation during the last two decades induced a higher warming and cloud level rise than that caused by climate change, which threatens biodiversity and water supply in African montane forests.
Published New insights on how bird flu crosses the species barrier
(via sciencedaily.com) Original source The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species.
Published Searching old stem cells that stay young forever
(via sciencedaily.com) Original source The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.
Published Preliminary study shows potential of Manuka honey as a nutraceutical for breast cancer
(via sciencedaily.com) Original source A new study found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment -- particularly for estrogen receptor (ER)-positive breast cancer, the most common subtype of breast cancer that accounts for about 70-80% of all breast cancer cases.
Published Nitrogen interventions as a key to better health and robust ecosystems
(via sciencedaily.com) Original source An international research team combined multidisciplinary methods to evaluate how nitrogen interventions could improve air quality and reduce nitrogen deposition. Their study found that interventions, such as improving fuel combustion conditions, increasing agricultural nitrogen use efficiency, and reducing food loss and waste, could significantly lower premature deaths attributed to air pollution, crop losses, and ecosystems risks.
Published Why isn't Colorado's snowpack ending up in the Colorado River? New research suggests the problem might be the lack of spring rainfall
(via sciencedaily.com) Original source The Colorado River and its tributaries provide water for hydropower, irrigation and drinking water in seven U.S. states and Mexico. But since 2000, water managers have struggled to predict how much water will come from the snowpack. The problem lies with the lack of rainfall in the spring, according to new research.
Published Probiotics during pregnancy shown to help moms and babies
(via sciencedaily.com) Original source Giving probiotics to pregnant mice can enhance both the immune system and behavior of the mothers and their offspring.
Published Zebrafish use surprising strategy to regrow spinal cord
(via sciencedaily.com) Original source A new study maps out a detailed atlas of all the cells involved in regenerating the zebrafish spinal cord. In an unexpected finding, the researchers showed that survival and adaptability of the severed neurons themselves is required for full spinal cord regeneration. Surprisingly, the study showed that stem cells capable of forming new neurons play a complementary role but don t lead the process.
Published Surprise finding in study of environmental bacteria could advance search for better antibiotics
(via sciencedaily.com) Original source Researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's 'envelope' or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.
Published Warming waters and nutrient overload: A dangerous combination threatening our rivers and lakes
(via sciencedaily.com) Original source New international research found that food webs are becoming less complex in warmer, nutrient-rich waters.
Published Fracking frenzy in India: A water crisis in the making?
(via sciencedaily.com) Original source India's plans to scale up fracking operations without robust regulations could spell disaster for the country's finely balanced water security, according to research.
Published Hydrometeorology and location affect hospitalizations for waterborne infectious diseases in the US
(via sciencedaily.com) Original source An analysis of 12 years of data collected from over 500 hospitals in 25 different states shows that weather, geographic location, and urban or rural location all appear to influence hospitalizations for waterborne infectious diseases.
Published Tropical Atlantic mixing rewrites climate pattern rules
(via sciencedaily.com) Original source Changes in the Atlantic Ocean's mixed layer are the primary force behind the Atlantic Multidecadal Variability (AMV).
Published Beige fat cells with a 'Sisyphus mechanism'
(via sciencedaily.com) Original source A new class of fat cells makes people healthier. The cells consume energy and produce heat through seemingly pointless biochemical reactions.
Published New mechanism of action kills cancer cells
(via sciencedaily.com) Original source Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the drugs ineffective. A research team now describes a new mechanism of action that kills cancer cells through ferroptosis.
Published A ketogenic diet could improve the response to pancreatic cancer therapy
(via sciencedaily.com) Original source Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Published Newly discovered ability of comammox bacteria could help reduce nitrous oxide emissions in agriculture
(via sciencedaily.com) Original source An international research team has discovered that comammox bacteria, first identified by them in 2015, can grow using guanidine, a nitrogen-rich organic compound, as their sole energy and nitrogen source. This unique ability opens new avenues for targeted cultivation of these enigmatic microbes and could also provide a key to reducing agricultural nitrous oxide emissions.