Showing 20 articles starting at article 201
< Previous 20 articles Next 20 articles >
Categories: Biology: Molecular, Environmental: Water
Published New deep-learning model outperforms Google AI system in predicting peptide structures
(via sciencedaily.com) Original source Researchers have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides -- chains of amino acids that are shorter than proteins, but perform similar biological functions. Peptides are known to be highly flexible, taking on a wide range of folding patterns, and are thus involved in many biological processes of interest to researchers in the development of therapeutics.
Published Pacific cod can't rely on coastal safe havens for protection during marine heat waves
(via sciencedaily.com) Original source During recent periods of unusually warm water in the Gulf of Alaska, young Pacific cod in near shore safe havens where they typically spend their adolescence did not experience the protective effects those areas typically provide, a new study found.
Published US Clean Water Act leaves about 55% of water flowing out of rivers vulnerable to pollution
(via sciencedaily.com) Original source The Supreme Court ruled last year that rivers that only flow in response to weather events -- called ephemeral streams -- do not fall under the protection of the Clean Water Act. New research suggests that this now leaves many U.S. waterways vulnerable to pollution.
Published A promising weapon against measles
(via sciencedaily.com) Original source What happens when measles virus meets a human cell? The viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane.
Published Potent therapy candidate for fatal prion diseases
(via sciencedaily.com) Original source Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic approaches to treat certain diseases.
Published New, holistic way to teach synthetic biology
(via sciencedaily.com) Original source Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published Climate change and sea level rise pose an acute challenge for cities with combined sewer systems
(via sciencedaily.com) Original source Older coastal cities, like Philadelphia, New York and Boston are at risk of being inundated by untreated sewage during floods. Due in part to the design of their combined sewer systems and in part due to sea level rise, these cities could be facing a growing public health crisis as climate change also drives more extreme precipitation. The group recently published research that modeled the potential extent of the problem in a section of the coastal city of Camden, New Jersey, and the effectiveness of one proposed intervention to help protect these communities.
Published Simple new process stores CO2 in concrete without compromising strength
(via sciencedaily.com) Original source By using carbonated -- rather than still -- water during the concrete manufacturing process, a team of engineers has discovered a new way to store carbon dioxide (CO2) in the ubiquitous construction material.
Published Researchers address ocean paradox with 55 gallons of fluorescent dye
(via sciencedaily.com) Original source Researchers have directly measured cold, deep water upwelling via turbulent mixing along the slope of a submarine canyon in the Atlantic Ocean.
Published From takeoff to flight, the wiring of a fly's nervous system is mapped
(via sciencedaily.com) Original source Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.
Published Cell division: Before commitment, a very long engagement
(via sciencedaily.com) Original source Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published Unlocking the world of bacteria
(via sciencedaily.com) Original source Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
Published The on-and-off affair in DNA
(via sciencedaily.com) Original source Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published Slipping a note to a neighbor: The cellular way
(via sciencedaily.com) Original source Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.
Published Some landfill 'burps' contain airborne PFAS
(via sciencedaily.com) Original source Many municipal landfills 'burp' gas from decomposing organic matter rather than letting it build up. And burps from buried waste containing per- and polyfluoroalkyl substances (PFAS) can release these 'forever chemicals' into the air, say researchers. Their study reports unexpectedly high levels of airborne PFAS at three landfills and demonstrates that vented gases and liquid by-products called leachates could transport similar amounts of these contaminants to the environment.
Published Small, adsorbent 'fins' collect humidity rather than swim through water
(via sciencedaily.com) Original source Clean, safe water is a limited resource and access to it depends on local bodies of water. But even dry regions have some water vapor in the air. To harvest small amounts of humidity, researchers developed a compact device with absorbent-coated fins that first trap moisture and then generate potable water when heated. They say the prototype could help meet growing demands for water, especially in arid locations.
Published Revealing the dynamic choreography inside multilayer vesicles
(via sciencedaily.com) Original source Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles -- structures that transport waste or food within cells. In a recent paper, researchers shed some light on how these vesicles self-assemble, knowledge that could help scientists design bio-inspired vesicles for drug-delivery or inspire them to create life-like synthetic materials.
Published Underwater mountains have a big impact on ocean circulation
(via sciencedaily.com) Original source Colossal undersea mountains, towering up to thousands of metres high, stir up deep sea currents: impacting how our ocean stores heat and carbon. An international team used numerical modelling to quantify how underwater turbulence around these mountains, called seamounts, influences ocean circulation; finding it is an important mechanism in ocean mixing and one that is missing from climate models used in policymaking.
Published Zebrafish reveal how bioelectricity shapes muscle development
(via sciencedaily.com) Original source New research describes how nerve cells and muscle cells communicate through electrical signals during development -- a phenomenon known as bioelectricity. The communication, which takes place via specialized channels between cells, is vital for proper development and behavior. The study identifies specific genes that control the process, and pins down what happens when it goes wrong. The finding offers clues to the genetic origins of muscle disorders in humans.
Published Discovery of vast sex differences in cellular activity has major implications for disease treatment
(via sciencedaily.com) Original source The study reveals vast differences in gene activity within the mitochondria of males compared to females. This is the first study to test effects of all 37 genes in the mitochondrial genome -- genes that copepods and humans share. The study found that males demonstrate more activity across all protein-coding mitochondrial genes than females. Although the study looks at tiny marine organisms called copepods, the findings have weighty implications for human medicine.