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Categories: Biology: Molecular, Environmental: Water
Published Engineers measure pH in cell condensates
(via sciencedaily.com) Original source In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.
Published Oregon State researchers take deep dive into how much water is stored in snow
(via sciencedaily.com) Original source There's a new metric that provides a more holistic look at how much water is stored in snowpack, and for how long.
Published Even inactive smokers are densely colonized by microbial communities
(via sciencedaily.com) Original source Everything is everywhere -- under certain conditions microbial communities can grow and thrive, even in places that are seemingly uninhabitable. This is the case at inactive hydrothermal vents on the sea floor. An international team is presently working to accurately quantify how much inorganic carbon can be bound in these environments.
Published Machine learning classifier accelerates the development of cellular immunotherapies
(via sciencedaily.com) Original source Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.
Published Protein fragments ID two new 'extremophile' microbes--and may help find alien life
(via sciencedaily.com) Original source Perfectly adapted microorganisms live in extreme environments from deep-sea trenches to mountaintops. Learning more about how these extremophiles survive in hostile conditions could inform scientists about life on Earth and potential life on other planets.
Published Small amounts of licorice raise blood pressure, study finds
(via sciencedaily.com) Original source It is known that large amounts of licorice cause high blood pressure. A new study now shows that even small amounts of licorice raise blood pressure. The individuals who react most strongly also show signs of strain on the heart.
Published Surprising insights about debris flows on Mars
(via sciencedaily.com) Original source The period that liquid water was present on the surface of Mars may have been shorter than previously thought. Channel landforms called gullies, previously thought to be formed exclusively by liquid water, can also be formed by the action of evaporating CO2 ice, according to a new study.
Published Alzheimer's drug fermented with help from AI and bacteria moves closer to reality
(via sciencedaily.com) Original source Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.
Published New bioengineered protein design shows promise in fighting COVID-19
(via sciencedaily.com) Original source A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.
Published Sleep-wake rhythm: Fish change our understanding of sleep regulation
(via sciencedaily.com) Original source Researchers have discovered that some fish -- unlike humans -- do not need orexin to stay awake. This molecule was thought to be necessary for normal wake and sleep rhythms in vertebrates. Humans without orexin suffer from narcolepsy.
Published New discovery reveals how the egg controls sperm entry
(via sciencedaily.com) Original source After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.
Published Even cells know the importance of recycling
(via sciencedaily.com) Original source Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.
Published Unique way to track carbon emissions in bodies of water
(via sciencedaily.com) Original source Carbon dioxide emissions are not typically associated with water ways, like streams and rivers, but emerging research shows that water bodies play an important role in storing and releasing carbon dioxide. As many states look for cost-effective ways to mitigate climate change, scientists looked at a way to optimize CO2 sensors to better measure carbon dioxide emissions in lotic, or moving, bodies of water offering a new tool that can help provide valuable information for everything from land use to climate action plans.
Published Sulfur and the origin of life
(via sciencedaily.com) Original source A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.
Published Asian aerosols' impact on Atlantic Meridional Overturning Circulation
(via sciencedaily.com) Original source A new study identifies the role aerosols over Asia is having on the AMOC, a complex system of currents in the Atlantic Ocean.
Published Tryptophan in diet, gut bacteria protect against E. coli infection
(via sciencedaily.com) Original source Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure.
Published With discovery of roundworms, Great Salt Lake's imperiled ecosystem gets more interesting
(via sciencedaily.com) Original source Biologists announce the discovery of numerous species of roundworm in the highly saline waters of Great Salt Lake, the vast terminal lake in northwestern Utah that supports millions of migratory birds. Previously, brine shrimp and brine flies were the only known multicellular animals living in the water column. The scientists found nematodes, belonging to a family known for inhabiting extreme environments, in the lake's microbialites, reef-like structures covering about a fifth of the lakebed.
Published Drought, soil desiccation cracking, and carbon dioxide emissions: an overlooked feedback loop exacerbating climate change
(via sciencedaily.com) Original source Soil stores 80 percent of carbon on earth, yet with increasing cycles of drought, that crucial reservoir is cracking and breaking down, releasing even more greenhouse gases creating an amplified feedback loop that could accelerate climate change.
Published 'Find pearls in the soil' unveiling the magic of hydrogen production from municipal sewage
(via sciencedaily.com) Original source Scientists have developed a catalyst for the urea oxidation reaction, enhancing hydrogen generation efficiency.
Published New computational strategy boosts the ability of drug designers to target proteins inside the membrane
(via sciencedaily.com) Original source Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.