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Categories: Biology: Molecular, Environmental: Water
Published 3D in vitro human atherosclerosis model for high-throughput drug screening



A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging



Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published Capturing greenhouse gases with the help of light



Researchers use light-reactive molecules to influence the acidity of a liquid and thereby capture of carbon dioxide. They have developed a special mixture of different solvents to ensure that the light-reactive molecules remain stable over a long period of time. Conventional carbon capture technologies are driven by temperature or pressure differences and require a lot of energy. This is no longer necessary with the new light-based process.
Published Spying on a shape-shifting protein



Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published Study uncovers potential origins of life in ancient hot springs



A research team investigated how the emergence of the first living systems from inert geological materials happened on the Earth, more than 3.5 billion years ago. Scientists found that by mixing hydrogen, bicarbonate, and iron-rich magnetite under conditions mimicking relatively mild hydrothermal vent results in the formation of a spectrum of organic molecules, most notably including fatty acids stretching up to 18 carbon atoms in length.
Published Even the oldest eukaryote fossils show dazzling diversity and complexity



The sun has just set on a quiet mudflat in Australia's Northern Territory; it'll set again in another 19 hours. A young moon looms large over the desolate landscape. No animals scurry in the waning light. No leaves rustle in the breeze. No lichens encrust the exposed rock. The only hint of life is some scum in a few puddles and ponds. And among it lives a diverse microbial community of our ancient ancestors.
Published Beaches and dunes globally squeezed by roads and buildings



Beaches and dunes globally squeezed by roads and buildings. Beaches and dunes are becoming increasingly trapped between rising sea levels and infrastructure. Researchers found that today, when dropped on a random beach anywhere in the world, you only need to walk 390 meters (on average) to find the nearest road or building. And while that short walking distance may seem convenient if you want a day at the beach, it's bad news for our protection against rising sea levels, drinking water supplies and biodiversity.
Published Lab-grown retinas explain why people see colors dogs can't



With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.
Published Highly durable, nonnoble metal electrodes for hydrogen production from seawater



The water electrolysis method, a promising avenue for hydrogen production, relies on substantial freshwater consumption, thereby limiting the regions available with water resources required for water electrolysis . Researchers have developed highly durable electrodes without precious metals to enable direct hydrogen production from seawater.
Published Protein complex discovered to control DNA repair



The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published Toxic algae blooms: Study assesses potential health hazards to humans



Water samples from 20 sites were tested using a panel of immortalized human cell lines corresponding to the liver, kidney and brain to measure cytotoxicity. Results show that each control toxin induced a consistent pattern of cytotoxicity in the panel of human cell lines assayed. Known toxins were seen only during blooms. Because cell toxicity was seen in the absence of blooms, it suggests that there might be either emergent toxins or a combination of toxins present at those times. Findings suggest that other toxins with the potential to be harmful to human health may be present in the lagoon.
Published Record heat in 2023 worsened global droughts, floods and wildfires



Record heat across the world profoundly impacted the global water cycle in 2023, contributing to severe storms, floods, megadroughts and bushfires, new research shows.
Published A new type of plant metalloreductase maintains root growth under low phosphorus



Phosphorus is essential for undisturbed plant growth and development. However, in many soils, phosphorus is only poorly available. One mechanism used by plants to increase phosphorus availability is the release of malate, an organic acid, which can form complexes with iron or aluminium in the soil, thereby liberating sorbed phosphate. However, this response can also result in iron overaccumulation, which can inhibit root growth.
Published PFAS flow equally between Arctic Ocean and Atlantic Ocean



The frigid Arctic Ocean is far removed from the places most people live, but even so, 'forever chemicals' reach this remote landscape. Now, research suggests that per- and polyfluoroalkyl substances (PFAS) won't stay there indefinitely. Instead, they are transported in a feedback loop, with the Arctic Ocean potentially exporting as many PFAS to the North Atlantic Ocean as it receives, circulating the compounds around the world.
Published Only 18% of the global land area that is needed for human well-being and biodiversity is currently protected



An international group of researchers finds that conserving about half of global land area could maintain nearly all of nature's contributions to people and still meet biodiversity targets for tens of thousands of species. But the same priority areas are at risk of conflict with human development with only 18% of that land area protected.
Published 'Carbon vault' peat suffers greatly from drought



Peatlands are affected more by drought than expected. This is concerning, as these ecosystems are an important ally in the fight against climate change. Following long periods of drought, peat is able to absorb little to no extra carbon (CO2). Increasing biodiversity also does little to make peat more drought-resilient.
Published Climate change behind sharp drop in snowpack since 1980s



A new study confirms that spring snowpacks across the Northern Hemisphere have shrunk significantly over the past 40 years due to human-driven climate change, putting hundreds of millions of people worldwide at risk of a water crisis. The Southwestern and Northeastern U.S. saw among the steepest declines, with more than 10% of the spring snowpack lost per decade, which the researchers expect will accelerate with further warming. Many heavily populated snow-dependent watersheds are dangerously near what they call a 'snow-loss cliff,' wherein once average winter temperatures exceed 17 degrees Fahrenheit, snow loss accelerates even with only modest increases in temperature.
Published Acidity of Antarctic waters could double by century's end, threatening biodiversity



Without drastically reducing global emissions, the Antarctic Ocean could become too acidic for hundreds of species living there, many already endangered by rising temperatures and sea ice loss.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne



An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Meteorite analysis shows Earth's building blocks contained water



Analysis of iron meteorites from the earliest years of the solar system indicate that the planetary 'seeds' that ultimately formed Earth contained water.