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Categories: Biology: Molecular, Geoscience: Geography
Published Beige fat cells with a 'Sisyphus mechanism'
(via sciencedaily.com) Original source A new class of fat cells makes people healthier. The cells consume energy and produce heat through seemingly pointless biochemical reactions.
Published New mechanism of action kills cancer cells
(via sciencedaily.com) Original source Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the drugs ineffective. A research team now describes a new mechanism of action that kills cancer cells through ferroptosis.
Published A ketogenic diet could improve the response to pancreatic cancer therapy
(via sciencedaily.com) Original source Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Published Climate change raised the odds of unprecedented wildfires in 2023-24
(via sciencedaily.com) Original source Unprecedented wildfires in Canada and parts of Amazonia last year were at least three times more likely due to climate change and contributed to high levels of CO2 emissions from burning globally, according to the a new systematic review. The State of Wildfires report takes stock of extreme wildfires of the 2023-2024 fire season (March 2023-February 2024), explains their causes, and assesses whether events could have been predicted. It also evaluates how the risk of similar events will change in future under different climate change scenarios.
Published Exciting advance in stem cell therapy
(via sciencedaily.com) Original source A new technique for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.
Published Changing food consumers' choices may help cut greenhouse gases
(via sciencedaily.com) Original source Planet-warming greenhouse gas emissions associated with the global food supply chains induced by diets could fall by 17% if people change their food choices towards more plant-based diets.
Published Surprising insight into cancer comes from unique plant species that find different solutions to evolutionary challenges
(via sciencedaily.com) Original source A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.
Published Expansion of agricultural land threatens climate and biodiversity
(via sciencedaily.com) Original source Food, feed, fiber, and bioenergy: The demand for agricultural raw materials is rising. How can additional cultivation areas be reconciled with nature conservation? Researchers have developed a land-use model that provides answers.
Published Rewriting the evolutionary history of critical components of the nervous system
(via sciencedaily.com) Original source A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.
Published The mother of all motion sensors
(via sciencedaily.com) Original source Researchers have used silicon photonic microchip components to perform a quantum sensing technique called atom interferometry, an ultra-precise way of measuring acceleration. It is the latest milestone toward developing a kind of quantum compass for navigation when GPS signals are unavailable.
Published Starvation and adhesion drive formation of keratinocyte patterns in skin
(via sciencedaily.com) Original source Cell-cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion researchers find.
Published Ships now spew less sulfur, but warming has sped up
(via sciencedaily.com) Original source New findings document fewer ship tracks, reduced cloud cover, and boosted warming after ship emissions regulations took effect in 2020.
Published New study unveils 16,000 years of climate history in the tropical Andes
(via sciencedaily.com) Original source Researchers highlight the roles of carbon dioxide and ocean currents as key drivers of temperature fluctuations in the tropical Andes over a 16,000 year period.
Published Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
(via sciencedaily.com) Original source Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. Oleoyl-ACP-hydrolase (OLAH) is an enzyme involved in fatty acid metabolism. A study shows that OLAH drives severe disease outcomes.
Published Researchers ID body's 'quality control' regulator for protein folding
(via sciencedaily.com) Original source Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.
Published Pre-surgical antibody treatment might prevent heart transplant rejection
(via sciencedaily.com) Original source Anti-rejection regimens currently in use are broad immunosuppressive agents that make patients susceptible to infections. By using specific antibodies, it may be possible to just block the inflammation that leads to rejection but leave anti-microbial immunity intact.
Published Balancing technology and governance are key to achieving climate goals
(via sciencedaily.com) Original source Despite advancements in clean energy, global CO2 emissions continue to rise. IIASA researchers contributed to a new international study that underscores the importance of integrating technological advancements with robust institutional capacities to formulate effective climate policies.
Published How mortal filaments' self-assemble and maintain order: Align or die
(via sciencedaily.com) Original source A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto 'dying to align': Misaligned filaments 'die' spontaneously to form a ring structure at the center of the dividing cell. The work could find applications in developing synthetic self-healing materials.
Published Taking a 'one in a million' shot to tackle dopamine-linked brain disorders
(via sciencedaily.com) Original source With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the Million Mutation Project (MMP) for the rapid identification of mutant genes based on their functional impact. They can seek insights from simpler organisms whose genes bear striking similarity to those found in humans and where opportunities for genetic insights to disease can be pursued more efficiently and inexpensively.
Published Just say 'climate change' -- not 'climate emergency'
(via sciencedaily.com) Original source The familiar terms 'climate change' and 'global warming' are more likely to resonate with people than other commonly used phrases.