Showing 20 articles starting at article 41
< Previous 20 articles Next 20 articles >
Categories: Biology: Molecular, Geoscience: Oceanography
Published Pre-surgical antibody treatment might prevent heart transplant rejection
(via sciencedaily.com) Original source Anti-rejection regimens currently in use are broad immunosuppressive agents that make patients susceptible to infections. By using specific antibodies, it may be possible to just block the inflammation that leads to rejection but leave anti-microbial immunity intact.
Published How mortal filaments' self-assemble and maintain order: Align or die
(via sciencedaily.com) Original source A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto 'dying to align': Misaligned filaments 'die' spontaneously to form a ring structure at the center of the dividing cell. The work could find applications in developing synthetic self-healing materials.
Published Taking a 'one in a million' shot to tackle dopamine-linked brain disorders
(via sciencedaily.com) Original source With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the Million Mutation Project (MMP) for the rapid identification of mutant genes based on their functional impact. They can seek insights from simpler organisms whose genes bear striking similarity to those found in humans and where opportunities for genetic insights to disease can be pursued more efficiently and inexpensively.
Published An appetizer can stimulate immune cells' appetite, a boon for cancer treatments
(via sciencedaily.com) Original source The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white blood cell that surveils tissues and consumes pathogens, debris, dead cells, and cancer. Macrophages have a delicate task. It's crucial that they ignore healthy cells while on patrol, otherwise they could trigger an autoimmune response while performing their duties.
Published A new mechanism for shaping animal tissues
(via sciencedaily.com) Original source A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be 'programmed' to transition from a flat state to a three-dimensional shape.
Published Largest protein yet discovered builds algal toxins
(via sciencedaily.com) Original source While seeking to unravel how marine algae create their chemically complex toxins, scientists have discovered the largest protein yet identified in biology. Uncovering the biological machinery the algae evolved to make its intricate toxin also revealed previously unknown strategies for assembling chemicals, which could unlock the development of new medicines and materials.
Published Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy
(via sciencedaily.com) Original source Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient. Now, researchers have developed a machine-learning approach that promises to speed up AAV engineering for gene therapy. The tool helps researchers engineer the protein shells of AAVs, called capsids, to have multiple desirable traits, such as the ability to deliver cargo to a specific organ but not others or to work in multiple species. Other methods only look for capsids that have one trait at a time.
Published Bacteria encode hidden genes outside their genome--do we?
(via sciencedaily.com) Original source A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.
Published Researchers develop AI model that predicts the accuracy of protein--DNA binding
(via sciencedaily.com) Original source A new artificial intelligence model can predict how different proteins may bind to DNA.
Published Researchers make breakthrough in understanding species abundance
(via sciencedaily.com) Original source The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.
Published Record-breaking recovery of rocks that originated in Earth's mantle could reveal secrets of planet's history
(via sciencedaily.com) Original source Scientists have recovered the first long section of rocks that originated in the Earth's mantle, the layer below the crust and the planet's largest component. The rocks will help unravel the mantle's role in the origins of life on Earth, the volcanic activity generated when it melts, and how it drives the global cycles of important elements such as carbon and hydrogen.
Published 3D bioprinting advances research on respiratory viruses
(via sciencedaily.com) Original source Researchers develop a microstructured 'artificial lung' model using bioprinting technology.
Published Microscopy technique 'paves way' for improving understanding of cellular functions
(via sciencedaily.com) Original source Scientists have developed a new way of counting labelled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.
Published How ribosomes in our cells enable protein folding
(via sciencedaily.com) Original source Scientists discovered a role played by ribosomes during the folding of new proteins in cells.
Published Viral defense protein speeds up female stem cell production
(via sciencedaily.com) Original source A viral defense mechanism can be used to accelerate the creation of female stem cell lines in mice. The findings can boost efforts in medical research, drug testing, and regenerative therapies, particularly for women and individuals with two X chromosomes.
Published Do smells prime our gut to fight off infection?
(via sciencedaily.com) Original source In nematodes and humans, mitochondrial stress in the nervous system initiates a whole-body response that is most pronounced in the gut. A recent study showed that in nematodes, the odor of a pathogen triggers the nervous system to broadcast this response to the rest of the organism, prepping mitochondria in intestinal cells to fight a bacterial infection. Humans, too, may be able to sense pathogenic odors that prepare the gut for an infection.
Published Discovering how plants make life-and-death decisions
(via sciencedaily.com) Original source Researchers have discovered two proteins that work in tandem to control an important response to cell stress.
Published South Florida estuaries warming faster than Gulf of Mexico, global ocean, USF research shows
(via sciencedaily.com) Original source Estuaries in South Florida have experienced rapid warming over the past two decades, including a record-breaking marine heat wave in 2023, research shows. The findings paint a troubling picture for the marine life that calls Florida home. Possible causes include evaporation, water capacity and residence time (the amount of time water spends in an estuary). No single factor has been identified as dominant.
Published The race to discover biodiversity: 11 new marine species and a new platform for rapid species description
(via sciencedaily.com) Original source A new paper describes a ground-breaking experiment that united 25 independent taxonomists from 10 countries. The initiative boasts the discovery of 11 new marine species from all over the globe, occurring at depths from 5.2 to 7081 meters. It also represents a significant step forward in accelerating the pace at which new marine species are described and published.
Published Greenland fossil discovery reveals increased risk of sea-level catastrophe
(via sciencedaily.com) Original source Seeds, twigs, and insect parts found under two miles of ice confirm Greenland's ice sheet melted in the recent past, the first direct evidence that the center -- not just the edges -- of the two-mile-deep ice melted away in the recent geological past. The new research indicates that the giant ice sheet is more fragile than scientists had realized until the last few years -- and reveals increased risk of sea-level catastrophe in a warmer future.