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Categories: Anthropology: General, Biology: Molecular
Published Preventing spread of parasitic DNA in our genomes
(via sciencedaily.com) Original source Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.
Published Water makes all the difference
(via sciencedaily.com) Original source Water is a major driving force in the formation of separate reaction compartments within cells.
Published A hygiene program for chromosomes
(via sciencedaily.com) Original source Researchers identified and characterized a new cellular compartment in vertebrate cells that might be a precursor of today's eucaryotic nucleus. The study reveals that mammalian cells recognize, cluster, sort and keep extrachromosomal DNA -- like transfected plasmid DNA and endogenous circular DNAs originating from telomeres of the chromosome -- away from chromosomal DNA. That suggests that there is a cell autonomous genome defense system.
Published Climate and human land use both play roles in Pacific island wildfires past and present
(via sciencedaily.com) Original source It’s long been understood that human settlement contributes to conditions that make Pacific Islands more susceptible to wildfires, such as the devastating Aug. 8 event that destroyed the Maui community of Lahaina. But a new study from fire scientist shows that climate is an undervalued part of the equation.
Published Researchers studied thousands of fertility attempts hoping to improve IVF
(via sciencedaily.com) Original source By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.
Published Edges cause cilia to quickly synchronize their beating pattern
(via sciencedaily.com) Original source Border regions can cause cilia to coordinate their motion creating a unidirectional wave that is essential for biological functions. Scientists proposed a new model describing this synchronized pattern driven by the border region.
Published Small but mighty new gene editor
(via sciencedaily.com) Original source A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders. The tool is an enzyme, AsCas12f, which has been modified to offer the same effectiveness but at one-third the size of the Cas9 enzyme commonly used for gene editing. The compact size means that more of it can be packed into carrier viruses and delivered into living cells, making it more efficient.
Published Insights into early snake evolution through brain analysis
(via sciencedaily.com) Original source Recent study sheds new light on the enigmatic early evolution of snakes by examining an unexpected source: their brains. The results emphasize the significance of studying both the soft parts of animals’ bodies and their bones for understanding how animals evolved.
Published A lethal parasite's secret weapon: Infecting non-immune cells
(via sciencedaily.com) Original source The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.
Published An advance in cryo-EM could be a significant boon for research on potential cancer therapies
(via sciencedaily.com) Original source A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules. A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they're being imaged, which will enable cryo-EM to produce much clearer images of such molecules. The advance is significant because small and medium-sized protein molecules are an area of focus in research on potential new drugs for cancer and other diseases.
Published A turtle time capsule: DNA found in ancient shell
(via sciencedaily.com) Original source Paleontologists discover possible DNA remains in fossil turtle that lived 6 million years ago in Panama, where continents collide.
Published New information on the most important early stage of embryonic development
(via sciencedaily.com) Original source A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development.
Published Tiny CRISPR tool could help shred viruses
(via sciencedaily.com) Original source Scientists mapped out the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems then used that knowledge to modify its structure and improve its accuracy.
Published Researchers discover disease-causing stem cells in lungs of cystic fibrosis patients
(via sciencedaily.com) Original source Experts in cloning and stem cell science are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis, and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.
Published A close-up of biological nanomachines: Researchers take a deep look at peroxisomal processes
(via sciencedaily.com) The cell organelles known as 'peroxisomes' dispose toxic substances and fats in the human body, among other things, and, in doing so, they prevent serious illnesses. The 'Pex' group of proteins (peroxisomes biogenesis factors) keep these 'detox units' functioning properly -- and now researchers have shown, at the atomic level, how these highly complex processes proceed.
Published Did life exist on Mars? Other planets? With AI's help, we may know soon
(via sciencedaily.com) Original source Scientists have discovered a simple and reliable test for signs of past or present life on other planets -- 'the holy grail of astrobiology.' Researchers report that, with 90% accuracy, their artificial intelligence-based method distinguished modern and ancient biological samples from those of abiotic origin.
Published Modelling of adhesive technology sheds new light on prehistoric cognition
(via sciencedaily.com) Original source Studying prehistoric production processes of birch bark tar using computational modelling reveals what kinds of cognition were required for the materials produced by Neanderthal and early modern humans.
Published Pollen analysis suggests peopling of Siberia and Europe by modern humans occurred during a major Pleistocene warming spell
(via sciencedaily.com) Original source A new study appearing in Science Advances compares Pleistocene vegetation communities around Lake Baikal in Siberia, Russia, to the oldest archeological traces of Homo sapiens in the region. The researchers use the 'remarkable evidence' to tell a compelling story from 45,000-50,000 years ago with new detail: how the first humans migrated across Europe and Asia.
Published Probing the deep genetic structure of Africa
(via sciencedaily.com) Original source Using ancestry decomposition techniques an international research team has revealed a deeply divergent ancestry among admixed populations from the Angolan Namib desert. This unique genetic heritage brings the researchers closer to understanding the distribution of genetic variation in the broader region of southern Africa before the spread of food production.
Published Same genes behind heart muscle disorders in humans and Dobermanns
(via sciencedaily.com) Original source Researchers have made a significant finding in determining the genetic background of dilated cardiomyopathy in Dobermanns. This research helps us understand the genetic risk factors related to fatal diseases of the heart muscle and the mechanisms underlying the disease, and offers new tools for their prevention.