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Categories: Anthropology: General, Biology: Molecular
Published This parasitic plant convinces hosts to grow into its own flesh--it's also an extreme example of genome shrinkage
(via sciencedaily.com) Original source Balanophora shed one third of its genes as it evolved into a streamlined parasitic plant -- an extreme degree of genome shrinkage even among parasites. Along the way this subtropical plant developed the ability to induce the host plant to grow into the parasite's own flesh -- forming chimeric organs that mix host and parasite tissues.
Published Dinosaur feathers reveal traces of ancient proteins
(via sciencedaily.com) Original source Palaeontologists have discovered X-ray evidence of proteins in fossil feathers that sheds new light on feather evolution.
Published Researchers develop first method to study microRNA activity in single cells
(via sciencedaily.com) Researchers have developed the first method to uncover the tasks that microRNAs perform in single cells. This is a huge improvement over existing state-of-the-art methods that require millions of cells and will for the first time allow researchers to study microRNAs in complex tissues such as brains.
Published New study reveals a long history of violence in ancient hunter-gatherer societies
(via sciencedaily.com) Original source Violence was a consistent part of life among ancient communities of hunter-gatherers, according to a new study that looked for signs of trauma on 10,000-year-old skeletal remains from burial sites in northern Chile.
Published Split gene-editing tool offers greater precision
(via sciencedaily.com) To make a gene-editing tool more precise and easier to control, engineers split it into two pieces that only come back together when a third molecule is added.
Published Scientists regenerate neurons that restore walking in mice after paralysis from spinal cord injury
(via sciencedaily.com) Original source In a new study in mice, researchers have uncovered a crucial component for restoring functional activity after spinal cord injury. The neuroscientists have shown that re-growing specific neurons back to their natural target regions led to recovery, while random regrowth was not effective.
Published Unzipping mRNA rallies plant cells to fight infection
(via sciencedaily.com) Original source Living things from plants to humans must constantly adjust the chemical soup of proteins -- the workhorse molecules of life -- inside their cells to adapt to stress or changing conditions. Now, researchers have identified a previously unknown molecular mechanism that helps explain how they do it. A team now reveals hairpin-like structures of mRNA that, by zipping and unzipping, help cells change the mix of proteins they produce when under stress.
Published Ritual use of human remains dating from the Neolithic
(via sciencedaily.com) Original source An international study has documented post-mortem bone modifications not linked to consumption.
Published Exercise and muscle regulation: Implications for diabetes and obesity
(via sciencedaily.com) Original source How do our muscles respond at the molecular level to exercise? Researchers have unraveled the cellular basis and signaling pathways responsible for the positive impact of physical activity on our overall health. Regulatory T cells, a type of immune cell, play a critical role in ensuring proper muscle function. These novel insights are paving the path towards precision medicines targeting metabolic disorders like obesity and diabetes, as well as muscle-related illnesses.
Published Ancient Amazonians intentionally created fertile 'dark earth'
(via sciencedaily.com) Original source A new study suggests patches of fertile soil in the Amazon, known as dark earth, were intentionally produced by ancient Amazonians as a way to improve the soil and sustain large and complex societies.
Published Archaeologists discover world's oldest wooden structure
(via sciencedaily.com) Original source Half a million years ago, earlier than was previously thought possible, humans were building structures made of wood, according to new research.
Published Slow growth in crocodile ancestors pre-dated their semi-aquatic lifestyle
(via sciencedaily.com) Original source A groundbreaking study is reshaping our understanding of crocodile evolution by pinpointing the onset of slow growth rates to the Late Triassic period, much earlier than the previously assumed Early Jurassic timeline. The research highlights newly discovered fossil crocodile ancestors (known as crocodylomorphs) that exhibited slow growth rates, similar to modern-day crocodilians. Intriguingly, these early crocodylomorphs were not the lethargic, semi-aquatic creatures we are familiar with today; they were small, active, and fully terrestrial. The study also suggests that this slow-growth strategy was not a mere evolutionary quirk but a survival mechanism, as only the slow-growing crocodylomorphs managed to survive the End-Triassic mass extinction. This stands in stark contrast to the fast-growing dinosaurs of the same era, setting the stage for the divergent evolutionary paths that would later define their modern descendants.
Published Artificial Intelligence tools shed light on millions of proteins
(via sciencedaily.com) Original source A research team has uncovered a treasure trove of uncharacterized proteins. Embracing the recent deep learning revolution, they discovered hundreds of new protein families and even a novel predicted protein fold.
Published Spider silk is spun by silkworms for the first time, offering a green alternative to synthetic fibers
(via sciencedaily.com) Scientists have synthesized spider silk from genetically modified silkworms, producing fibers six times tougher than the Kevlar used in bulletproof vests. The study is the first to successfully produce full-length spider silk proteins using silkworms. The findings demonstrate a technique that could be used to manufacture an environmentally friendly alternative to synthetic commercial fibers such as nylon.
Published Prehistoric fish fills 100 million year gap in evolution of the skull
(via sciencedaily.com) Original source X-rays of an ancient jawless fish shows earliest-known example of internal cartilage skull, unlike that of any other known vertebrate.
Published Imaging the smallest atoms provides insights into an enzyme's unusual biochemistry
(via sciencedaily.com) A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational changes, that help to explain the enzyme's biochemistry. This work might help researchers engineer enzymes that facilitate unusual chemistry or are highly efficient at room temperature that are useful in chemical industry.
Published Tiny sea creatures reveal the ancient origins of neurons
(via sciencedaily.com) Original source A new study sheds new light on the origins of modern brain cells. Researchers find evidence that specialized secretory cells found in placozoans, tiny sea creatures the size of a grain of sand, have many similarities to the neuron, such as the genes required to create a partial synapse. From an evolutionary point of view, early neurons might have started as something like these cells, eventually gaining the ability to create a complete synapse, form axons and dendrites and create ion channels that generate fast electrical signals -- innovations which gave rise to the neuron in more complex animals such as jellyfish. Though the complete story of how the first neuron appeared remains to be told, the study demonstrates that the basic building blocks for our brain cells were forming in the ancestors of placozoans grazing inconspicuously in the shallow seas of Earth around 800 million years ago.
Published Buried ancient Roman glass formed substance with modern applications
(via sciencedaily.com) Original source Researchers discover how molecules in ancient glass rearrange and recombine with minerals over centuries to form a patina of photonic crystals -- ordered arrangements of atoms that filter and reflect light in very specific ways -- an analog of materials used in communications, lasers and solar cells.
Published Tracking down the formation of cardenolides in plants
(via sciencedaily.com) Original source Scientists are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. In a new study, they present two enzymes from the CYP87A family as key enzymes that catalyze the formation of pregnenolone, the precursor for the biosynthesis of plant steroids, in two different plant families. The discovery of such enzymes should help to develop platforms for the cheap and sustainable production of high quality steroid compounds for medical use.
Published Genome editing: Reducing off-target mutations in DNA
(via sciencedaily.com) Original source Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded 'nicks' in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.