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Categories: Anthropology: General, Biology: Molecular
Published Researchers successfully induce primate oocytes in the lab



The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.
Published The fast and the fibrous: Developing the muscles you need for speed



Researchers have identified the role of the large Maf transcription factor family in regulating fast twitch muscle fibers. A mouse model lacking Maf expression in the skeletal muscles exhibited a significant loss of type IIb myofibers, a subtype of fast twitch fibers. Overexpression of large Mafs promoted type IIb muscle fiber induction. The large Maf family may represent potential targets for developing treatments for muscular disorders involving fast twitch fibers.
Published How tasty is the food?



A hormone and specialized brain cells regulate feeding behavior in mice.
Published Where do our limbs come from?



Scientists have uncovered new clues about the origin of paired appendages -- a major evolutionary step that remains unresolved and highly debated.
Published A look into the heart of cellular waste disposal



Researchers reveal how a nanomachine takes care of cleaning up inside the cell.
Published Engineers create bacteria that can synthesize an unnatural amino acid



Researchers have engineered bacteria to synthesize an amino acid that contains a rare functional group that others have shown to have implications in the regulation of our immune system. The researchers also taught a single bacterial strain to create the amino acid and place it at specific sites within target proteins. These findings provide a foundation for developing unique vaccines and immunotherapies in the future.
Published Researchers find new mechanism for sodium salt detoxification in plants



A team of researchers has found a mechanism in thale cress (Arabidopsis thaliana) which enables plants to provide protection against salt stress for their sensitive stem cells in the meristem at the root tip.
Published A multiomics approach provides insights into flu severity



Researchers were able to identify changes in the accessibility (that is, the 'readability') of transposable elements. To do this, the researchers used an approach combining various sets of multiomics data, which characterize and quantify collections of biomolecules in cells or organisms. One was the transcriptome, which consists of all copies of RNA transcribed from DNA in the cell. The other was the epigenome, which is the collection of chemical changes to DNA that modify gene expression. An advantage of this multiomics approach is that they were able to identify families of transposable elements with changes in accessibility, which would have likely been missed by previous approaches.
Published Designing synthetic receptors for precise cell control



Scientists have developed a groundbreaking new technique for engineering biosensors that respond sensitively to specific biomolecules, enhancing cell migration and targeting in cancer treatment. The findings could lead to more precise control over cellular processes for a wide range of therapeutic applications.
Published Dinosaurs were the first to take the perspectives of others



Understanding that others hold different viewpoints from your own is essential for human sociality. Adopting another person's visual perspective is a complex skill that emerges around the age of two. A new study suggests that this ability first arose in dinosaurs, at least 60 million years before it appeared in mammals. These findings challenge the idea that mammals were the originators of novel and superior forms of intelligence in the wake of the dinosaur extinction.
Published Under control to the very end -- how our cells kill themselves



Every day, millions of cells die in our body. Other than generally assumed, cells do not simply burst at the end of their lives but rather, a specific protein serves as a breaking point for cell membrane rupture. Researchers have now been able to elucidate the exact mechanism at the atomic level.
Published A guide through the genome



Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests. One of the greatest challenges in modern plant research is to identify the differences in genetic information that are responsible for this variation.
Published How plants use sugar to produce roots



Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. Botanists have demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to the research team leader.
Published Earliest evidence of wine consumption in the Americas found in Caribbean



Scientists have found what they believe to be the earliest known evidence of wine drinking in the Americas, inside ceramic artefacts recovered from a small Caribbean island.
Published Synthetic biology: proteins set vesicles in motion



Biophysicists have designed a new cell-like transport system that represents an important milestone on the road to artificial cells.
Published Humanity's earliest recorded kiss occurred in Mesopotamia 4,500 years ago



Written sources from Mesopotamia suggest that kissing in relation to sex was practiced by the peoples of the ancient Middle East 4,500 years ago.
Published Cancer cells use a new fuel in absence of sugar



Researchers have discovered a new nutrient source that pancreatic cancer cells use to grow. The molecule, uridine, offers insight into both biochemical processes and possible therapeutic pathways. The findings show that cancer cells can adapt when they don't have access to glucose.
Published Watch these cells rapidly create protrusions for exploration and movement



In order to move, cells must be able to rapidly change shape. A team of researchers show that cells achieve this by storing extra 'skin' in folds and bumps on their surface. This cell surface excess can be rapidly deployed to cover temporary protrusions and then folded away for next time.
Published Scales or feathers? It all comes down to a few genes



Scales, spines, feathers and hair are examples of vertebrate skin appendages, which constitute a remarkably diverse group of micro-organs. Despite their natural multitude of forms, these appendages share early developmental processes at the embryonic stage. Researchers have discovered how to permanently transform the scales that normally cover the feet of chickens into feathers, by specifically modifying the expression of certain genes.
Published A channel involved in pain sensation can also suppress it



Pain is good. It's the body's way to keep an animal from harming itself or repeating a dangerous mistake. But sometimes the debilitating sensation can get in the way. So evolution has devised ways to tamp that response down under certain circumstances.