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Categories: Anthropology: General, Biology: Molecular
Published Scientists discover the dynamics of an 'extra' chromosome in fruit flies
(via sciencedaily.com) Original source Most chromosomes have been around for millions of years. Now, researchers have revealed the dynamics of a new, very young chromosome in fruit flies that is similar to chromosomes that arise in humans and is associated with treatment-resistant cancer and infertility. The findings may one day lead to developing more targeted therapies for treating these conditions.
Published Research reveals longstanding cultural continuity at oldest occupied site in West Africa
(via sciencedaily.com) Original source Stone tools recovered from near the Senegalese coast extend occupation of the region back to 150 thousand years ago and are comparable to those seen across Africa at this time, but uniquely persist in the region until 10 thousand years ago.
Published Scientists recover an ancient woman's DNA from a 20,000-year-old pendant
(via sciencedaily.com) Original source An international research team has for the first time successfully isolated ancient human DNA from a Paleolithic artefact: a pierced deer tooth discovered in Denisova Cave in southern Siberia. To preserve the integrity of the artefact, they developed a new, nondestructive method for isolating DNA from ancient bones and teeth. From the DNA retrieved they were able to reconstruct a precise genetic profile of the woman who used or wore the pendant, as well as of the deer from which the tooth was taken. Genetic dates obtained for the DNA from both the woman and the deer show that the pendant was made between 19,000 and 25,000 years ago. The tooth remains fully intact after analysis, providing testimony to a new era in ancient DNA research, in which it may become possible to directly identify the users of ornaments and tools produced in the deep past.
Published A novel stem cell adhesive using mussels
(via sciencedaily.com) Original source A team of researchers develops stem cell adhesive for arthritis treatment using mussel adhesion protein and hyaluronic acid.
Published Scientists present evidence for a billion-years arms race between viruses and their hosts
(via sciencedaily.com) Original source Researchers have proposed a new evolutionary model for the origin of a kingdom of viruses called Bamfordvirae, suggesting a billion-years evolutionary arms race between two groups within this kingdom and their hosts.
Published Wiggly proteins guard the genome
(via sciencedaily.com) Original source Dynamic network in the pores of the nuclear envelope blocks dangerous invaders.
Published Do people and monkeys see colors the same way?
(via sciencedaily.com) Original source New findings in color vision research imply that humans can perceive a greater range of blue tones than monkeys do. Distinct connections found in the human retina may indicate recent evolutionary adaptations for sending enhanced color vision signals from the eye to the brain.
Published Previously unknown intercellular electricity may power biology
(via sciencedaily.com) Original source Researchers have discovered that the electrical fields and activity that exist through a cell's membrane also exist within and around another type of cellular structure called biological condensates. Like oil droplets floating in water, these structures exist because of differences in density. Their foundational discovery could change the way researchers think about biological chemistry. It could also provide a clue as to how the first life on Earth harnessed the energy needed to arise.
Published New research redefines mammalian tree of life
(via sciencedaily.com) Original source Scientists from around the globe are using the largest mammalian genomic dataset in history to determine the evolutionary history of the human genome in the context of mammalian evolutionary history. Their ultimate goal is to better identify the genetic basis for traits and diseases in people and other species.
Published Artificial photosynthesis for environmentally friendly food production
(via sciencedaily.com) Original source Ensuring the supply of food to the constantly growing world population and protecting the environment at the same time are often conflicting objectives. Now researchers have successfully developed a method for the synthetic manufacture of a nutritional protein using a type of artificial photosynthesis. The animal feed industry is the primary driver of high demand for large volumes of this nutritional protein L-alanine, which is also suitable for use in meat substitute products.
Published Scientists identify antivirals that could combat emerging infectious diseases
(via sciencedaily.com) Original source A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.
Published Scientists slow aging by engineering longevity in cells
(via sciencedaily.com) Original source Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Published Pulling the plug on viral infections: CRISPR isn't just about cutting
(via sciencedaily.com) Original source CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses. A new study reveals a previously unrecognized player in one such system -- a membrane protein that enhances anti-viral defense. According to study authors, the finding upends the idea that CRISPR systems mount their defense only by degrading RNA and DNA in cells.
Published Information 'deleted' from the human genome may be what made us human
(via sciencedaily.com) Original source What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.
Published How dormant bacteria come back to life
(via sciencedaily.com) Original source Bacterial spores can survive for years, even centuries, without nutrients, resisting heat, UV radiation, and antibiotics. How inert, sleeping bacteria -- or spores -- spring back to life has been a century-long mystery. New research identifies how sensor proteins revive dormant bacteria. Discovery opens new routes to combat spore resistance to antibiotics and sterilization. Findings can inform novel strategies to prevent infections, food spoilage.
Published Elephant ecosystems in decline
(via sciencedaily.com) Original source Global space for Asian elephant habitats has been in rapid decline since the 1700s, a new report reveals. More than 3 million square kilometers of the Asian elephant's historic habitat range has been lost in just three centuries and may underlie present-day conflicts between elephants and people.
Published Prolonged droughts likely spelled the end for Indus megacities
(via sciencedaily.com) Original source New research has found evidence -- locked into an ancient stalagmite from a cave in the Himalayas -- of a series of severe and lengthy droughts which may have upturned the Bronze Age Indus Civilization.
Published Brain circuits for locomotion evolved long before appendages and skeletons
(via sciencedaily.com) Original source Scientists found parallels between the neural circuitry that guides locomotion in sea slugs and in more complex animals like mammals.
Published Near-universal T cell immunity towards a broad range of bacteria
(via sciencedaily.com) Original source Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner.
Published Luring the virus into a trap
(via sciencedaily.com) Original source Viruses like influenza A and Ebola invade human cells in a number of steps. Research teams investigated the final stages of viral penetration using electron tomography and computer simulations. So-called fusion pores, through which the viral genome is released into the host cell, play a central role in these processes. If they can be prevented from forming, the virus is also blocked. The Heidelberg scientists describe previously unknown mechanisms, which might lead to new approaches to prevent infections.