Showing 20 articles starting at article 261

< Previous 20 articles        Next 20 articles >

Categories: Anthropology: Cultures, Biology: Molecular

Return to the site home page

     (via sciencedaily.com)     Original source 

A collaboration unveils a novel strategy for identifying key proteins in organelle communication. This approach advances our ability to pinpoint proteins essential for organelle interactions within specific spatial and temporal contexts.

     (via sciencedaily.com)     Original source 

The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.

     (via sciencedaily.com)     Original source 

Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.

     (via sciencedaily.com)     Original source 

Researchers have discovered the neural circuitry in the spinal cord that allows brain-independent motor learning. The study found two critical groups of spinal cord neurons, one necessary for new adaptive learning, and another for recalling adaptations once they have been learned. The findings could help scientists develop ways to assist motor recovery after spinal cord injury.

     (via sciencedaily.com)     Original source 

Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.

     (via sciencedaily.com)     Original source 

New evidence of one of the first cities in the Pacific shows they were established much earlier than previously thought, according to new research. The study used aerial laser scanning to map archaeological sites on the island of Tongatapu in Tonga, showing Earth structures were being constructed in Tongatapu around AD 300.

     (via sciencedaily.com)     Original source 

Astrophysicists shed light on the relationship between the Milky Way and the Egyptian sky-goddess Nut. The paper draws on ancient Egyptian texts and simulations to argue that the Milky Way might have shone a spotlight, as it were, on Nut's role as the sky. It proposes that in winter, the Milky Way highlighted Nut's outstretched arms, while in summer, it traced her backbone across the heavens.

     (via sciencedaily.com)     Original source 

Cells contain various specialized structures -- such as the nucleus, mitochondria or peroxisomes -- known as 'organelles'. Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction.

     (via sciencedaily.com)     Original source 

A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.

     (via sciencedaily.com)     Original source 

Researchers have developed a novel method of adding polyethylene glycol molecules to engineered groups of messenger RNAs called 'mRNA polyplexes', which enable the cells that receive them to produce specific proteins. This technique allows greater control of the site in the body to which the polyplexes are delivered, significantly advancing the field of therapeutic mRNA technologies, with applications in vaccine development and the treatment of cancer and other diseases.

     (via sciencedaily.com)     Original source 

Researchers decode repair mechanism during transcription of genetic information.

     (via sciencedaily.com)     Original source 

Through the ages, the presence of humans has increased the heterogeneity and complexity of ecosystems and has often had a positive effect on their biodiversity.

     (via sciencedaily.com)     Original source 

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.

     (via sciencedaily.com)     Original source 

Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.

     (via sciencedaily.com)     Original source 

Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.

     (via sciencedaily.com)     Original source 

Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.

     (via sciencedaily.com)     Original source 

Biophysicists have demonstrated how heat flows through rock fissures could have created the conditions for the emergence of life.

     (via sciencedaily.com)     Original source 

Researchers have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have developed computational tools capable of predicting these protein-RNA interactions. The newfound ability to predict these interactions can help future work in understanding molecular pathways in the cell and pave the way for developing drugs targeting these RNA G-quadruplex binding proteins, that are found to be involved in disease such as cancer.

     (via sciencedaily.com)     Original source 

A new study finds that UCYN-A, a species of nitrogen-fixing cyanobacteria, may be evolving organelle-like characteristics.

     (via sciencedaily.com)     Original source 

A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study reveals the role of a sugar called sialic acid in this invasion process. The findings have major implications for malaria vaccine and drug development.