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Categories: Archaeology: General, Biology: Molecular
Published Cell division quality control 'stopwatch' uncovered
(via sciencedaily.com) Original source Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.
Published Ancient DNA reveals the appearance of a 6th century Chinese emperor
(via sciencedaily.com) Original source What did an ancient Chinese emperor from 1,500 years ago look like? A team of researchers reconstructed the face of Chinese Emperor Wu of Northern Zhou using DNA extracted from his remains. The study suggests the emperor's death at the age of 36 might be linked to a stroke. It also sheds light on the origin and migration patterns of a nomadic empire that once ruled parts of northeastern Asia.
Published Connecting the dots to shape growth forces
(via sciencedaily.com) Original source Branching patterns are prevalent in our natural environment and the human body, such as in the lungs and kidneys. For example, specific genes that express growth factor proteins are known to influence the development of the lungs' complex branches. Researchers have unveiled a regulatory system linking signal, force, and shape in mouse lung structure development. The team recognized that the signal protein ERK plays an active role in causing growing lung tissue to curve.
Published New technique for predicting protein dynamics may prove big breakthrough for drug discovery
(via sciencedaily.com) Original source Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions.
Published Researchers show that introduced tardigrade proteins can slow metabolism in human cells
(via sciencedaily.com) Original source Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.
Published Discovery of amino acid unveils how light makes plants open
(via sciencedaily.com) Original source Scientists have uncovered a unique mechanism that regulates the opening of stomata in plants. Phosphorylation of the amino acid Thr881 on the plasma membrane proton pump plays a key role in this process. The study paves the way for the targeted manipulation of plant physiology, with potential applications in agriculture and environmental sustainability.
Published Uncovering the mystery of Dorset's Cerne Giant
(via sciencedaily.com) Original source For centuries, the Cerne Giant, a figure carved into a hillside in Dorset, has fascinated locals and visitors to the area. A new paper proposes that the Cerne Giant can in fact be dated to the early Middle Ages, and, as a result, its cultural context and significance more clearly understood.
Published Persian plateau unveiled as crucial hub for early human migration out of Africa
(via sciencedaily.com) Original source A new study combining genetic, palaeoecological, and archaeological evidence has unveiled the Persian Plateau as a pivotal geographic location serving as a hub for Homo sapiens during the early stages of their migration out of Africa. It highlights the period between 70,000 to 45,000 years ago when human populations did not uniformly spread across Eurasia, leaving a gap in our understanding of their whereabouts during this time frame.
Published Natural recycling at the origin of life
(via sciencedaily.com) Original source How was complex life able to develop on the inhospitable early Earth? At the beginning there must have been ribonucleic acid (RNA) to carry the first genetic information. To build up complexity in their sequences, these biomolecules need to release water. On the early Earth, which was largely covered in seawater, that was not so easy to do.
Published Scientists uncover evidence that microplastics are contaminating archaeological remains
(via sciencedaily.com) Original source A team of archaeologists discovered tiny microplastic particles in deposits located more than seven meters deep, in samples dating back to the first or early second century and excavated in the late 1980s.
Published Tudor era horse cemetery in Westminster revealed as likely resting place for elite imported animals
(via sciencedaily.com) Original source Archaeological analysis of a near unique animal cemetery discovered in London nearly 30 years ago has revealed there was an international horse trading network, orchestrated by the elites of late medieval and Tudor England, which brought superior physical specimens to the UK for jousting and for use as status symbols.
Published As we age, our cells are less likely to express longer genes
(via sciencedaily.com) Original source Aging may be less about specific 'aging genes' and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers. A decline in the expression of long genes with age has been observed in a wide range of animals, from worms to humans, in various human cell and tissue types, and also in individuals with neurodegenerative disease. Mouse experiments show that the phenomenon can be mitigated via known anti-aging factors, including dietary restriction.
Published Researchers name prehistoric amphibian ancestor discovered in Smithsonian collection after Kermit the Frog
(via sciencedaily.com) Original source Scientists have uncovered the fossilized skull of a 270-million-year-old ancient amphibian ancestor in the collection of the Smithsonian's National Museum of Natural History. The team of researchers described the fossil as a new species of proto-amphibian, which they named Kermitops gratus in honor of the iconic Muppet, Kermit the Frog.
Published Natural molecule found in coffee and human body increases NAD+ levels, improves muscle function during aging
(via sciencedaily.com) Original source A research consortium made a recent discovery that the natural molecule trigonelline present in coffee, fenugreek, and also in the human body, can help to improve muscle health and function.
Published Decoding the plant world's complex biochemical communication networks
(via sciencedaily.com) Original source A research team has begun translating the complex molecular language of petunias. Their grammar and vocabulary are well hidden, however, within the countless proteins and other compounds that fill floral cells. Being rooted to the ground, plants can't run away from insects, pathogens or other threats to their survival. But plant scientists have long known that they do send warnings to each other via scent chemicals called volatile organic compounds.
Published Study reveals 'cozy domesticity' of prehistoric stilt-house dwellers in England's ancient marshland
(via sciencedaily.com) Original source Detailed reports on thousands of artifacts pulled from 'Britain's Pompeii' reveals the surprisingly sophisticated domestic lives of Bronze Age Fen folk some 3,000 years ago -- from home interiors to recipes, clothing, kitchenware and pets.
Published New archive of ancient human brains challenges misconceptions of soft tissue preservation
(via sciencedaily.com) Original source A new study has challenged previously held views that brain preservation in the archaeological record is extremely rare. The team compiled a new archive of preserved human brains, which highlighted that nervous tissues actually persist in much greater abundances than traditionally thought, assisted by conditions that prevent decay.
Published A protein found in human sweat may protect against Lyme disease
(via sciencedaily.com) Original source Human sweat contains a protein that may protect against Lyme disease. About one-third of the population carries a genetic variant of this protein that is associated with Lyme disease in genome-wide association studies.
Published How cells are ahead of the curve
(via sciencedaily.com) Original source The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.
Published Engineers measure pH in cell condensates
(via sciencedaily.com) Original source In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.