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Categories: Archaeology: General, Biology: Molecular
Published The future of canine stem cell therapy: unprecedented, painless, and feeder-free



Scientists have developed an efficient, non-invasive, and pain-free method to generate canine-induced pluripotent stem cells (iPSCs). They identified six reprogramming genes that can boost canine iPSC generation by 120 times compared to conventional methods using fibroblasts. The iPSCs were created from urine-derived cells without the need for feeder cells, an impossible feat until now. Their findings are expected to advance regenerative medicine and genetic disease research in veterinary medicine.
Published The key mechanism to cell growth has been elucidated



Researchers have discovered how amino acids activate a key cell, TORC1, which is a master regulator in living organisms that controls whether cells grow or recycle their contents in yeast. Notably, the team found that the amino acid cysteine is sensed by a protein called Pib2 and that the two bind together to trigger TORC1. This is important because faulty TORC1 has been linked to disease such as cancer.
Published Bugs that help bugs: How environmental microbes boost fruit fly reproduction



A research group found that in female fruit flies, microorganisms enhance reproductive function, boosting the number of cells that form eggs and the number of mature eggs. This is done by controlling the release of hormones to speed up cell division in the ovaries, and limiting programmed cell death. These findings could improve reproductive medicine and could aid the development of new methods to enhance fertility.
Published First high mountain settlers at the start of the Neolithic already engaged in other livestock activities apart from transhumance



An archaeological find in the Huescan Pyrenees allowed researchers to identify for the first time livestock management strategies and feeding practices which demonstrate how the first high mountain societies, at the start of the Neolithic period, were already carrying out complex livestock and farming activities, instead of being limited to the transhumance of sheep and goats.
Published Researchers solve mystery behind DnaA protein's role in DNA replication initiation



Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic resistance.
Published New insights revealed on tissue-dependent roles of JAK signaling in inflammation



Researchers have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.
Published How researchers are 'CReATiNG' synthetic chromosomes faster and cheaper



A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes. Potential applications are numerous, including pharmaceutical production, biofuel generation, cancer therapies, and environmental cleanup using modified organisms. The method adds a powerful, versatile tool to the burgeoning field of synthetic biology.
Published Discovery: Plants use 'Trojan horse' to fight mold invasions



Scientists have discovered that plants send tiny, innocuous-seeming lipid 'bubbles' filled with RNA across enemy lines, into the cells of the aggressive mold. Once inside, different types of RNA come out to suppress the infectious cells that sucked them in.
Published A trillion scents, one nose



A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.
Published Cells of the future: A key to reprogramming cell identities



The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.
Published Study unveils a role of mitochondria in dietary fat processing



Researchers discover a new mechanism controlling the uptake of lipids from digested food.
Published Rise of archery in Andes Mountains dated to 5,000 years ago -- earlier than previous research



Focusing on the Lake Titicaca Basin in the Andes mountains, anthropologists found through analysis of 1,179 projectile points that the rise of archery technology dates to around 5,000 years ago. Previous research held that archery in the Andes emerged around 3,000 years ago. The new research from UC Davis indicates that the adoption of bow-and-arrow technology coincided with both the expansion of exchange networks and the growing tendency for people to reside in villages.
Published The evolutionary timeline of diminished boric acid and urea transportation in aquaporin 10



Aquaporin (Aqp) 10 water channels in humans allow the free passage of water, glycerol, urea, and boric acid across cells. However, Aqp10.2b in pufferfishes allows only the passage of water and glycerol and not urea and boric acid. Researchers sought to understand the evolutionary timeline that resulted in the variable substrate selection mechanisms among Aqp10s. Their results indicate that Aqp10.2 in ray-finned fishes may have reduced or lost urea and boric acid permeabilities through evolution.
Published New study examines the relationship between the rate of wound healing, the circadian rhythm, and 'hair' on cells



Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis. Most cells in mammalian bodies have cilia of some sort, which are hair-like structures that perform a variety of functions such as movement for motile cilia and aiding in structure in function for non-motile, or primary, cilia. The primary cilia also act as a sensory organ for the cell, a function which has illuminated the primary cilia's potential role in the healing process and how bodies heal at a different rate according to our circadian rhythm. In this research, the role of the primary cilia, biological clock and wound healing is explored.
Published Protein allows poison dart frogs to accumulate toxins safely



A newly identified protein helps poison dart frogs accumulate and store a potent toxin in their skin which they use for self-defence against predators.
Published Single-celled protists in the guts of animals thrive without the 'powerhouse of the cell'



Almost all eukaryotic organisms, from plants and animals to fungi, can't survive without mitochondria -- the 'powerhouses of the cell,' which generate chemical energy using oxygen. However, a new study finds that multiple members of the oxymonads, a group of single-celled protists that live inside the guts of termites and other animals, have evolved to live quite happily without them.
Published Mesopotamian bricks unveil the strength of Earth's ancient magnetic field



Ancient bricks inscribed with the names of Mesopotamian kings have yielded important insights into a mysterious anomaly in Earth's magnetic field 3,000 years ago, according to a new study.
Published Algae as a surprising meat alternative and source of environmentally friendly protein



A new study has demonstrate that the ingestion of two of the most commercially available algal species are rich in protein which supports muscle remodeling in young healthy adults. Their findings suggest that algae may be an interesting and sustainable alternative to animal-derived protein with respect to maintaining and building muscle.
Published New method Ebola virus uses to infect cells



Scientists recently published findings indicating that Ebola virus creates and uses intercellular tunnels to move from cell to cell and evade treatments.
Published Genetic atlas detailing early stages of zebrafish development



Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.