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Categories: Archaeology: General, Biology: Molecular
Published Acid sensor and calcium store discovered in plants
(via sciencedaily.com) Original source Using optogenetics, researchers have detected a new acid sensor in plant cells that is addressing a cell-internal calcium store.
Published Opportunities to improve future HIV vaccine candidates
(via sciencedaily.com) Original source An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study. The study findings draw comparisons between the immune system activity of past HIV vaccine study participants and people with HIV who naturally keep the virus from replicating even in the absence of antiretroviral therapy (ART). The latter individuals are often called 'long-term non-progressors' or 'elite controllers' (LTNPs/ECs).
Published How the immune system fights to keep herpes at bay
(via sciencedaily.com) Original source In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.
Published AI provides more accurate analysis of prehistoric and modern animals, painting picture of ancient world
(via sciencedaily.com) Original source A new study of the remains of prehistoric and modern African antelopes found that AI technology accurately identified animals more than 90% of the time compared to humans, who had much lower accuracy rates depending on the expert.
Published New understanding of ancient genetic parasite may spur medical breakthroughs
(via sciencedaily.com) Original source Researchers have determined the structure of the most common material in our genomes. New treatments for autoimmune diseases, cancer and neurodegeneration may follow.
Published Viking dentistry was surprisingly advanced
(via sciencedaily.com) Original source Widespread caries and toothache -- but also some dental work and filing of front teeth. Viking Age teeth from Varnhem bear witness to surprisingly advanced dentistry.
Published Enzymes can't tell artificial DNA from the real thing
(via sciencedaily.com) Original source Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
Published 'A ticking clock': First ground-based survey of damage to Ukrainian cultural sites reveals severity, need for urgency
(via sciencedaily.com) Original source And after nearly two years of fighting, war is destroying Ukraine’s cultural heritage on a scale not seen since World War II, according to new research.
Published Scientists unveil complete cell map of a whole mammalian brain
(via sciencedaily.com) Original source Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.
Published Cells move in groups differently than they do when alone
(via sciencedaily.com) Original source A protein that helps generate the force needed for single cells to move works differently in cells moving in groups, a new study shows.
Published Mice possess natural gene therapy system
(via sciencedaily.com) Original source A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
Published A rare enzyme role change with bacterial defense system assembly
(via sciencedaily.com) Original source Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
Published A sugar analysis could reveal different types of cancer
(via sciencedaily.com) Original source In the future, a little saliva may be enough to detect an incipient cancer. Researchers have developed an effective way to interpret the changes in sugar molecules that occur in cancer cells.
Published Archaeologists unearth one of earliest known frame saddles
(via sciencedaily.com) Original source Recovered from looters, a new archaeological discovery from a cave in western Mongolia could change the story of the evolving relationship between humans and horses around the world.
Published A new mechanism by which rotavirus makes you sick
(via sciencedaily.com) Original source Scientists report a new mechanism by which rotavirus induces diarrhea by interfering with the normal absorption of nutrients in the intestine.
Published Zika's shape-shifting machinery, and a possible vulnerability
(via sciencedaily.com) Original source Viruses have limited genetic material -- and few proteins -- so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins. Now researchers have shown how the virus does so much with so little and may have identified a therapeutic vulnerability.
Published How immune cells recognize their enemies
(via sciencedaily.com) Original source In order for immune cells to do their job, they need to know against whom they should direct their attack. Research teams a have identified new details in this process.
Published New genes can arise from nothing
(via sciencedaily.com) Original source The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers resolved outstanding questions regarding the origin of small regulatory genes, and described a mechanism that creates their DNA palindromes. Under suitable circumstances, these palindromes evolve into microRNA genes.
Published Ancient DNA analysis reveals how the rise and fall of the Roman Empire shifted populations in the Balkans
(via sciencedaily.com) Original source Despite the Roman Empire's extensive military and cultural influence on the nearby Balkan peninsula, a DNA analysis of individuals who lived in the region between 1 and 1000 CE found no genetic evidence of Iron Age Italian ancestry. Instead, a new study has revealed successive waves of migrations from Western Anatolia, central and northern Europe, and the Pontic-Kazakh Steppe during the Empire's reign.
Published Fungus-fighting protein could help overcome severe autoimmune disease and cancer
(via sciencedaily.com) Original source A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research has found. The discovery could pave the way for new and more effective drugs, without the nasty side effects of existing treatments. In addition to helping to manage severe autoimmune conditions, the breakthrough could also help treat all types of cancer.