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Categories: Archaeology: General, Biology: Molecular
Published A channel involved in pain sensation can also suppress it



Pain is good. It's the body's way to keep an animal from harming itself or repeating a dangerous mistake. But sometimes the debilitating sensation can get in the way. So evolution has devised ways to tamp that response down under certain circumstances.
Published Researchers reveal DNA repair mechanism



A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.
Published South Africa's desert-like interior may have been more inviting to our human ancestors



Lining the Cape of South Africa and its southern coast are long chains of caves that nearly 200,000 years ago were surrounded by a lush landscape and plentiful food.
Published How superbug A. baumannii survives metal stress and resists antibiotics



The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response. The World Health Organization (WHO) recognizes it as one of the three top pathogens in critical need of new antibiotic therapies. Now, an international team, led by Macquarie University researchers Dr. Ram Maharjan and Associate Professor Amy Cain, have discovered how the superbug can survive harsh environments and then rebound, causing deadly infections. They have found a single protein that acts as a master regulator. When the protein is damaged, the bug loses its superpowers allowing it to be controlled, in a lab setting. The research is published this month in Nucleic Acids Research.
Published Phage structure captured, to benefit biotech applications



Researchers have mapped out what a commonly-used form of phage looks like, which will help design better uses in future.
Published A look inside stem cells helps create personalized regenerative medicine



Researchers have examined a specific type of stem cell with an intracellular toolkit to determine which cells are most likely to create effective cell therapies.
Published Ancestral mitoviruses discovered in mycorrhizal fungi



A new group of mitochondrial viruses confined to the arbuscular mycorrhizal fungi Glomeromycotina may represent an ancestral lineage of mitoviruses.
Published Tooth enamel provides clues to hunter-gatherer lifestyle of Neanderthals



A study has given an intriguing glimpse of the hunting habits and diets of Neanderthals and other humans living in western Europe.
Published Evidence of Ice Age human migrations from China to the Americas and Japan



Scientists have used mitochondrial DNA to trace a female lineage from northern coastal China to the Americas. By integrating contemporary and ancient mitochondrial DNA, the team found evidence of at least two migrations: one during the last ice age, and one during the subsequent melting period. Around the same time as the second migration, another branch of the same lineage migrated to Japan, which could explain Paleolithic archeological similarities between the Americas, China, and Japan.
Published Scientists develop gene silencing DNA enzyme that can target a single molecule



Researchers have developed a DNA enzyme -- or DNAzyme -- that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact. This breakthrough 'gene silencing' technology could revolutionize the development of DNAzymes for treating cancer, infectious diseases and neurological disorders.
Published T cells can activate themselves to fight tumors



Scientists find an auto-signaling mechanism driving the T cell anti-tumor response; findings may inspire new cancer therapeutics and biomarkers.
Published New probe aids novel findings on cell functions



New research shows the use of a new cellular probe helped discover new findings about certain cellular processes.
Published Elucidating the mysteries of enzyme evolution at the macromolecular level



Researchers have made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their work points to potential applications in health, including the development of new drugs to treat serious diseases such as cancer or to counter antibiotic resistance.
Published Researchers close to unleashing rapeseed's protein power for human consumption



Half of plant proteins in the EU come from rapeseed plants. Until now, the plant has only been used for oil and animal feed, as it is both bitter and unsafe for human consumption. In a new study, researchers have gotten closer to removing the plant's bitter substances, and in doing so, are paving the way for a new protein source to support the green transition.
Published Archaeologists map hidden NT landscape where first Australians lived more than 60,000 years ago



Scientists have used sub-surface imaging and aerial surveys to see through floodplains in the Red Lily Lagoon area of West Arnhem Land in Australia. These ground-breaking methods showed how this important landscape in the Northern Territory was altered as sea levels rose about 8,000 years ago.
Published AI could run a million microbial experiments per year



Automation uncovers combinations of amino acids that feed two bacterial species and could tell us much more about the 90% of bacteria that humans have hardly studied. An artificial intelligence system enables robots to conduct autonomous scientific experiments -- as many as 10,000 per day -- potentially driving a drastic leap forward in the pace of discovery in areas from medicine to agriculture to environmental science.
Published Alternative 'fuel' for string-shaped motors in cells



Researchers discover a unique two-component molecular motor that uses a kind of renewable chemical energy to pull vesicles toward membrane-bound organelles.
Published Scientists discover the dynamics of an 'extra' chromosome in fruit flies



Most chromosomes have been around for millions of years. Now, researchers have revealed the dynamics of a new, very young chromosome in fruit flies that is similar to chromosomes that arise in humans and is associated with treatment-resistant cancer and infertility. The findings may one day lead to developing more targeted therapies for treating these conditions.
Published Scientists recover an ancient woman's DNA from a 20,000-year-old pendant



An international research team has for the first time successfully isolated ancient human DNA from a Paleolithic artefact: a pierced deer tooth discovered in Denisova Cave in southern Siberia. To preserve the integrity of the artefact, they developed a new, nondestructive method for isolating DNA from ancient bones and teeth. From the DNA retrieved they were able to reconstruct a precise genetic profile of the woman who used or wore the pendant, as well as of the deer from which the tooth was taken. Genetic dates obtained for the DNA from both the woman and the deer show that the pendant was made between 19,000 and 25,000 years ago. The tooth remains fully intact after analysis, providing testimony to a new era in ancient DNA research, in which it may become possible to directly identify the users of ornaments and tools produced in the deep past.
Published A novel stem cell adhesive using mussels



A team of researchers develops stem cell adhesive for arthritis treatment using mussel adhesion protein and hyaluronic acid.