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Categories: Archaeology: General, Biology: Molecular

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Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources. But now, a team has developed a sensitive method that analyzes viral nucleic acids in as little as 20 minutes and can be completed in one step with 'glow-in-the-dark' proteins.

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A new study has found evidence of cheesemaking, using milk from multiple animals in Late Neolithic Poland.

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A new study explores exactly what leads to the generation of Th17 cells -- an important subtype of cells in the intestine -- and uncovers some of the underappreciated molecular players and events that lead to cell differentiation in the gut.

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With the aid of some sea slugs, chemists have discovered that one of the smallest conceivable tweaks to a biomolecule can elicit one of the grandest conceivable consequences: directing the activation of neurons. The team has shown that the orientation of a single amino acid -- in this case, one of dozens found in the neuropeptide of a sea slug -- can dictate the likelihood that the peptide activates one neuron receptor versus another. Because different types of receptors are responsible for different neuronal activities, the finding points to another means by which a brain or nervous system can regulate the labyrinthine, life-sustaining communication among its cells.

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Peru's first great empire, the Wari, stretched for more than a thousand miles over the Andes Mountains and along the coast from 600-1000 CE. The pottery they left behind gives archaeologists clues as to how the empire functioned. In a new study researchers showed that rather than using 'official' Wari pottery imported from the capital, potters across the empire were creating their own ceramics, decorated to emulate the traditional Wari style. To figure it out, the scientists analyzed the pottery's chemical make-up, with help from laser beams.

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Researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced. The new mouse model shows milder cognitive traits compared to a previously studied Down syndrome mouse model.

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Scientists have done research that opens up a whole new world within our cells. Their study uncovers a vast network of interactions that assist cells in adjusting in real time to withstand stresses on our health.

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Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis which is critical for meiotic recombination and genetically diverse gametes. An international research team reports the application of a TurboID (TbID)-based approach to identify proteins in proximity of meiotic chromosome axes in Arabidopsis thaliana. Not only known but also new meiotic proteins were uncovered.

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A whole new world of antibiotics is waiting inside the viruses that infect bacteria. Scientists are making it easier to study them.

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Surprisingly, bitter taste receptors are not only located in the mouth, but also elsewhere in the body, including the airways. Activating those receptors opens up lung passageways, so they're a potential target for treating asthma or chronic obstructive pulmonary disease (COPD). Now, researchers report that they have designed a potent and selective compound that could lead the way to such therapies.

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Researchers have discovered artefacts produced by old world monkeys in Thailand that resemble stone tools, which historically have been identified as intentionally made by early hominins. Until now, sharp-edged stone tools were thought to represent the onset of intentional stone tool production, one of the defining and unique characteristics of hominin evolution. This new study challenges long held beliefs about the origins of intentional tool production in our own lineage.

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The skeleton, tendons, and glands of a functional jaw all derive from the same population of stem cells, which arise from a cell population known as neural crest. To discover how these neural crest-derived cells know to make the right type of cell in the right location, researchers focused on a particular gene, Nr5a2, that was active in a region of the face that makes tendons and glands, but not skeleton. To understand the role of Nr5a2, the scientists created zebrafish lacking this gene. These mutant zebrafish generated excess cartilage and were missing tendons in their jaws.

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Strong electric fields can be used to create pores in biomembranes. The method is known as electroporation. Inducing such defects in membranes in a targeted manner is an important technique in medicine and biotechnology, but also in the treatment of foodstuffs.

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Most cells in the bodies of living things duplicate their contents and physically separate into new cells through the process of cell division. But across many species, germ cells, those that become eggs or sperm, don't fully separate. They remain interconnected through small bridges called ring canals and cluster together. In a new study, researchers uncover how it is that germ cells in fruit flies form these ring canals, a finding that they say will provide new insights into a widely shared feature of development and into diseases in which cell division is disrupted.

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New methodology and tools provide an opportunity to watch in unprecedented detail as a phage attacks a bacterium.

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Obese fruit flies are the experimental subjects in a study of the causes of muscle function decline due to obesity. In humans, skeletal muscle plays a crucial role in metabolism, and muscle dysfunction due to human obesity can lead to insulin resistance and reduced energy levels.

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Researchers have discovered evidence of horse riding by studying the remains of human skeletons found in burial mounds called kurgans, which were between 4500-5000 years old. The earthen burial mounds belonged to the Yamnaya culture. The Yamnayans had migrated from the Pontic-Caspian steppes to find greener pastures in today's countries of Romania and Bulgaria up to Hungary and Serbia.

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Once upon a time, prevailing scientific opinion might have pronounced recently published research as unneeded. Now, climate change implications have heightened the need for this line of research. Flowers emit scent chemicals called volatile organic compounds (VOCs). Earlier this year, a study identified a protein that plays a key role in helping petunias emit volatiles.

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Some cities only last a century or two, while others last for a thousand years or more. Often, there aren't clear records left behind to explain why. Instead, archaeologists piece together clues from the cities' remains to search for patterns that help account for why certain places retained their importance longer than others.

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An international team of bee researchers has integrated a calcium sensor into honey bees to enable the study of neural information processing including response to odors. This also provides insights into how social behavior is located in the brain.