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Categories: Biology: Molecular, Paleontology: Dinosaurs

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Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Researchers discover key to molecular mystery of how plants respond to changing conditions      (via sciencedaily.com)     Original source 

A team of researchers recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change -- either internally or in the external environment -- to thrive in good times or survive the bad times? The research, focused on plants, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development      (via sciencedaily.com)     Original source 

Scientists can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts. Such knowledge opens the door to predictions of which enhancer variants underlie disease in order to harness the full potential of our genomes for better human health.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Computer Science: General
Published

Computer-engineered DNA to study cell identities      (via sciencedaily.com)     Original source 

A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. It will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based immunotherapies.

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Marine Biology: Microbiology Biology: Molecular Ecology: Sea Life Geoscience: Earth Science Geoscience: Geochemistry Geoscience: Geography Geoscience: Oceanography
Published

Vitamin B12 adaptability in Antarctic algae has implications for climate change, life in the Southern Ocean      (via sciencedaily.com)     Original source 

The algae P. antarctica has two forms of the enzyme that makes the amino acid methionine, one needing B12, and one that is slower, but doesn't need it. This means it has the ability to adapt and survive with low B12 availability. The presence of the MetE gene in P. antarctica gives the algae the ability to adapt to lower vitamin B12 availability, giving it a potential advantage to bloom in the early austral spring when bacterial production is low. P. antarctica takes in the CO2 and releases oxygen through photosynthesis. Understanding its ability to grow in environments with low vitamin B12 availability can help climate modelers make more accurate predictions.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Scientists see an ultra-fast movement on surface of HIV virus      (via sciencedaily.com)     Original source 

Seeing a glycoprotein on the envelope of the HIV virus snap open and shut in mere millionths of a second is giving investigators a new handle on the surface of the virus that could lead to broadly neutralizing antibodies for an AIDS vaccine. Being able to attach an antibody specifically to this little structure that would prevent it from popping open would be key.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Mechanism discovered that protects tissue after faulty gene expression      (via sciencedaily.com)     Original source 

A study has identified a protein complex that is activated by defects in the spliceosome, the molecular scissors that process genetic information. Future research could lead to new therapeutic approaches to treat diseases caused by faulty splicing.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Disrupted cellular function behind type 2 diabetes in obesity      (via sciencedaily.com)     Original source 

Disrupted function of 'cleaning cells' in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not. A study describes this newly discovered mechanism.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

A clutch stretch goes a long way      (via sciencedaily.com)     Original source 

New results reveal a new mode of force transmission in which dynamic molecular stretching bridges the extracellular matrix and flowing F-actin moving at different speeds. This discovery underscores the necessity of molecular elasticity and random coupling for sufficiently transmitting force. The findings also call for revising the role of molecular unfolding.

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Endangered Species
Published

Plant receptors that control immunity and development share a common origin      (via sciencedaily.com)     Original source 

Researchers have traced the origin and evolutionary trajectory of plant immune receptors. Their discovery will make it easier to identify immune receptor genes from genomic information and could help in the development of pathogen-resistant crops.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Gut bacteria can process dietary fiber into an anti-allergy weapon      (via sciencedaily.com)     Original source 

Short-chain fatty acids (SCFAs), which are produced by gut bacteria from dietary fiber, regulate our immune system, but the mechanism of their action remains unknown. In a recent study, researchers investigated how SCFAs interact with mast cells, a type of white blood cell that plays a central role in allergic reactions. Their findings and insights could lead to innovative and effective anti-allergy medications, supplements, and diets, paving the way for healthier lives.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Shining a new light on the tug-of-war between virus and host      (via sciencedaily.com)     Original source 

The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Environmental: General Geoscience: Geochemistry
Published

How seahorse-like toxins kill insects      (via sciencedaily.com)     Original source 

Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells      (via sciencedaily.com)     Original source 

New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.

Biology: Biochemistry Biology: Evolutionary Biology: General Biology: Zoology Paleontology: Dinosaurs Paleontology: Early Mammals and Birds Paleontology: Fossils Paleontology: General
Published

Scientists pinpoint growth of brain's cerebellum as key to evolution of bird flight      (via sciencedaily.com)     Original source 

Evolutionary biologists report they have combined PET scans of modern pigeons along with studies of dinosaur fossils to help answer an enduring question in biology: How did the brains of birds evolve to enable them to fly?

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Ecology: Endangered Species Ecology: Invasive Species Ecology: Nature Ecology: Trees Environmental: General
Published

Asparagus and orchids are more similar than you think      (via sciencedaily.com)     Original source 

How is a beech leaf constructed? What determines the appearance of an asparagus? A new 'encyclopaedia' helps us learn more about the building blocks of plants. The encyclopaedia, probably the largest of its kind, could be used to improve targeted plant breeding efforts, to make them both more climate-resilient and more easily digestible.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

'Genomic time machine' reveals secrets of our DNA      (via sciencedaily.com)     Original source 

Researchers reveal a novel method to uncover bits of our genetic blueprint that come from ancient genetic parasites, offering fresh insights into human evolution and health.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Biology: Zoology
Published

A non-allergenic wheat protein for growing better cultivated meat      (via sciencedaily.com)     Original source 

As the world's population increases, cultivated or lab-grown meat -- animal muscle and fat cells grown in laboratory conditions -- has emerged as a potential way to satisfy future protein needs. And edible, inexpensive plant proteins could be used to grow these cell cultures. Now, researchers report that the non-allergenic wheat protein glutenin successfully grew striated muscle layers and flat fat layers, which could be combined to produce meat-like textures.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular
Published

How obesity dismantles our mitochondria      (via sciencedaily.com)     Original source 

Researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain. They also found they could reverse the effect by targeting a single gene, suggesting a new treatment strategy for obesity.