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Categories: Biology: Molecular, Paleontology: Early Mammals and Birds
Published Laser-powered 'tweezers' reveal universal mechanism viruses use to package up DNA
(via sciencedaily.com) Original source Researchers have used laser-powered ‘optical tweezers’ to reveal a universal motor mechanism used by viruses for packaging their DNA into infectious particles.
Published Unearthing how a carnivorous fungus traps and digests worms
(via sciencedaily.com) Original source A new analysis sheds light on the molecular processes involved when a carnivorous species of fungus known as Arthrobotrys oligospora senses, traps and consumes a worm.
Published Coffee grounds may hold key to preventing neurodegenerative diseases
(via sciencedaily.com) Original source A team of researchers found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by several neurodegenerative diseases.
Published Heart repair via neuroimmune crosstalk
(via sciencedaily.com) Original source Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers now report.
Published New method to help with analysis of single cell data
(via sciencedaily.com) Original source CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout. The ability to study cells concurrently offers unprecedented insights into new cell types, disease states or other conditions. While CITE-seq solves the problem of detecting a limited number of proteins while using single-cell sequencing in an unbiased way, one of its limitations is the high levels of background noise that can hinder analysis.
Published Like the phoenix, Australia's giant birds of prey rise again from limestone caves
(via sciencedaily.com) Original source Australia's only vulture, and a fearsome extinct eagle, are among the earliest recorded birds of prey from the Pleistocene period more than 50,000 years ago -- and now researchers are bringing them to 'life' again. Along with new scientific information, a bold new pictorial reconstruction of a newly named eagle and the only known Australian vulture will be unveiled at the World Heritage-listed Naracoorte Caves in South Australia's Limestone Coast this month.
Published Genomic tug of war could boost cancer therapy
(via sciencedaily.com) Original source Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine draws this gene activator away from coding DNA, causing gene expression to grind to a halt and cells to die. However, many types of cancer have very high levels of H2A.Z, which may help them overcome this decitabine-induced tug of war, allowing the cancer to grow.
Published How cell identity is preserved when cells divide
(via sciencedaily.com) Original source A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation. Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.
Published Much more than waste: Tiny vesicles exchange genetic information between cells in the sea
(via sciencedaily.com) Original source Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.
Published Hormones have the potential to treat liver fibrosis
(via sciencedaily.com) Original source Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition. Currently, there are no drugs available to treat liver fibrosis.
Published Birds set foot near South Pole in Early Cretaceous, Australian tracks show
(via sciencedaily.com) Original source The discovery of 27 avian footprints on the southern Australia coast -- dating back to the Early Cretaceous when Australia was still connected to Antarctica -- opens another window onto early avian evolution and possible migratory behavior.
Published Plants that survived dinosaur extinction pulled nitrogen from air
(via sciencedaily.com) Original source Ancient cycad lineages that survived the extinction of the dinosaurs may have done so by relying on symbiotic bacteria in their roots to fix atmospheric nitrogen. The finding came from an effort to understand ancient atmospheres, but became an insight into plant evolution instead.
Published How bacteria recognize viral invasion and activate immune defenses
(via sciencedaily.com) Original source Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.
Published Colliding ribosomes activate RNA repair
(via sciencedaily.com) Original source Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage.
Published Novel C. diff structures are required for infection, offer new therapeutic targets
(via sciencedaily.com) Original source Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles.
Published A tale of two proteins: Fundamental research could make growing better crops like clockwork
(via sciencedaily.com) Original source Rhomboid-like protein 10, or RBL10, is thought to be an enzyme that degrades other proteins in the chloroplast membrane, but its function is largely unknown. Researchers are studying how RBL10 affects photosynthetic membrane lipid metabolism, an essential process in photosynthesis.
Published New discovery on how green algae count cell divisions illuminates key step needed for the evolution of multicellular life
(via sciencedaily.com) Original source An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division.
Published How marine bristle worms use a special protein to distinguish between sunlight and moonlight
(via sciencedaily.com) Original source A research team has presented its findings on the functioning of an atypical cryptochrome protein (Cry). These proteins are found in a variety of organisms, and they are often involved in light-controlled biological processes. The marine bristle worm Platynereis dumerilii, for example, employs a special Cry protein designated L-Cry to distinguish between sunlight and moonlight as well as between different moon phases. This is essential for the worms to synchronize their reproduction to the full moon phase via an inner monthly calendar, also called circalunar clock.
Published Ground-breaking discovery could pave the way for new therapies to prevent cardiovascular disease and stroke
(via sciencedaily.com) Original source Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives.
Published The Goldilocks Effect: Researchers establish framework for protein regulation
(via sciencedaily.com) Original source Researchers are working to understand how protein quality control works in cells.