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Categories: Biology: Molecular, Chemistry: General
Published Pre-surgical antibody treatment might prevent heart transplant rejection



Anti-rejection regimens currently in use are broad immunosuppressive agents that make patients susceptible to infections. By using specific antibodies, it may be possible to just block the inflammation that leads to rejection but leave anti-microbial immunity intact.
Published How mortal filaments' self-assemble and maintain order: Align or die



A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto 'dying to align': Misaligned filaments 'die' spontaneously to form a ring structure at the center of the dividing cell. The work could find applications in developing synthetic self-healing materials.
Published Taking a 'one in a million' shot to tackle dopamine-linked brain disorders



With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the Million Mutation Project (MMP) for the rapid identification of mutant genes based on their functional impact. They can seek insights from simpler organisms whose genes bear striking similarity to those found in humans and where opportunities for genetic insights to disease can be pursued more efficiently and inexpensively.
Published An appetizer can stimulate immune cells' appetite, a boon for cancer treatments



The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white blood cell that surveils tissues and consumes pathogens, debris, dead cells, and cancer. Macrophages have a delicate task. It's crucial that they ignore healthy cells while on patrol, otherwise they could trigger an autoimmune response while performing their duties.
Published A new mechanism for shaping animal tissues



A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be 'programmed' to transition from a flat state to a three-dimensional shape.
Published New mechanism to cool buildings while saving energy



The movement of radiant heat -- felt when a hot surface warms our bodies and homes -- between buildings and their surroundings at ground level makes buildings with less skyward-facing surfaces harder to cool. A research team has demonstrated a new passive cooling technology that coats walls and windows with materials that can better manage heat movement between buildings and their surroundings at ground level. Findings could reduce the reliance on air conditioning and provide a more environmentally friendly, low-cost and scalable option for low-income communities with limited or no access to cooling and heating systems.
Published Largest protein yet discovered builds algal toxins



While seeking to unravel how marine algae create their chemically complex toxins, scientists have discovered the largest protein yet identified in biology. Uncovering the biological machinery the algae evolved to make its intricate toxin also revealed previously unknown strategies for assembling chemicals, which could unlock the development of new medicines and materials.
Published Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy



Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient. Now, researchers have developed a machine-learning approach that promises to speed up AAV engineering for gene therapy. The tool helps researchers engineer the protein shells of AAVs, called capsids, to have multiple desirable traits, such as the ability to deliver cargo to a specific organ but not others or to work in multiple species. Other methods only look for capsids that have one trait at a time.
Published Bacteria encode hidden genes outside their genome--do we?



A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.
Published Researchers develop AI model that predicts the accuracy of protein--DNA binding



A new artificial intelligence model can predict how different proteins may bind to DNA.
Published Pioneering plasma-catalytic process for CO2 hydrogenation to methanol under ambient conditions



A research team reports a pioneering plasma-catalytic process for the hydrogenation of CO2 to methanol at room temperature and atmospheric pressure. This breakthrough addresses the limitations of traditional thermal catalysis, which often requires high temperatures and pressures, resulting in low CO2 conversion and methanol yield.
Published 3D laser printing with bioinks from microalgae



Microalgae such as the diatom Odontella aurita and the green alga Tetraselmis striata are especially suitable as 'biofactories' for the production of sustainable materials for 3D laser printing due to their high content in lipids and photoactive pigments. An international research team has succeeded for the first time in manufacturing inks for printing complex biocompatible 3D microstructures from the raw materials extracted from the microalgae.
Published Researchers make breakthrough in understanding species abundance



The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.
Published New technology uses light to engrave erasable 3D images



Researchers invented a technique that uses a specialized light projector and a photosensitive chemical additive to imprint two- and three-dimensional images inside any polymer. The light-based engraving remains in the polymer until heat or light are applied, which erases the image and makes it ready to use again. The technology is intended for any situation where having detailed, precise visual data in a compact and easily customizable format could be critical, such as planning surgeries and developing architectural designs.
Published Finding pearls in the mud: Eco-friendly tungsten recovery from semiconductor waste



Semiconductor industry waste is typically seen as a costly disposal problem and an environmental hazard. But what if this waste could be transformed into a valuable resource? In an exciting development, researchers have unveiled an eco-friendly method to extract rare metals from semiconductor waste. This innovative approach not only recovers precious tungsten but also assesses its economic viability, offering a sustainable solution for waste management in the tech industry.
Published 3D bioprinting advances research on respiratory viruses



Researchers develop a microstructured 'artificial lung' model using bioprinting technology.
Published Effective new catalyst brings hope for cleaner energy, wastewater treatment, and green chemistry



A catalyst that significantly enhances ammonia conversion could improve wastewater treatment, green chemical and hydrogen production.
Published Microscopy technique 'paves way' for improving understanding of cellular functions



Scientists have developed a new way of counting labelled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.
Published Chemists develop new sustainable reaction for creating unique molecular building blocks



Polymers can be thought of like trains: Just as a train is composed of multiple cars, polymers are made up of multiple monomers, and the couplings between the train cars are similar to the chemical bonds that link monomers together. While polymers have myriad applications -- from drug delivery to construction materials -- their structures and functions are restricted by the chemically similar monomer building blocks they're composed of. Now, chemists have developed a new reaction to create unique monomers in a controlled way. This reaction, which uses nickel as a catalyst, ultimately enables scientists to create polymers with unique and modifiable properties for drug delivery, energy storage, microelectronics and more.
Published Artificial compound eye to revolutionize robotic vision at lower cost but higher sensitivity



A research team has recently developed a novel artificial compound eye system that is not only more cost-effective, but demonstrates a sensitivity at least twice that of existing market products in small areas. The system promises to revolutionize robotic vision, enhance robots' abilities in navigation, perception and decision-making, while promoting commercial application and further development in human-robot collaboration.