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Categories: Biology: Molecular, Paleontology: Fossils

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Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year. Repeated sequencing of the virus RNA showed that the virus incorporated various parts of the host's messenger RNA into its genome. This resulted in a replication advantage, which may have contributed to the infection becoming chronic.

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While smell plays a considerable role in the social interactions of humans -- for instance, signaling fear or generating closeness -- for ants, it is vitally important. Researchers have found that a key protein named Orco, essential for the function of olfactory cells, is also critical for the cells' survival in ants.

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Ancient apes in Germany co-existed by partitioning resources in their environment, according to a new study.

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By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

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Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.

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What species live in this coral reef, and are they healthy? Chemical clues emitted by marine organisms might hold that information. But in underwater environments, invisible compounds create a complex 'soup' that is hard for scientists to decipher. Now, researchers have demonstrated a way to extract and identify these indicator compounds in seawater. They found metabolites previously undetected on reefs, including three that may represent different reef organisms.

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Researchers have been investigating the molecular mechanisms responsible for determining sex in ants. Although the vast majority of an ant colony consists of female workers, males are essential to the continuing survival of the species. In order to uncover the mechanisms involved, the researchers decided to focus on diploid males, which occasionally occur in the Argentine ant.

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Researchers provide the first insight into the mode of action of the lipopeptide serrawettin W2-FL10, derived from Serratia marcescens. This lipopeptide targets the cell membrane of S. aureus, causing lesions which result in the leakage of intracellular components and ultimately cell death.

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The swirl of milk and espresso -- a small storm in your mug -- doesn't impact the dynamics of the milk proteins, according to research. Researchers took a molecular view of how milk proteins and caffeine molecules interact in water and in a coffee drink. The results suggest that the structures of milk proteins remain intact, meaning they retain their original mouthfeel and taste in your morning brew.

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In a parasitic first, a Baltic amber specimen has revealed that millions of years ago tiny worms known as nematodes were living inside of and feeding on the outer protective layer of pseudoscorpions.

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The identity of a prehistoric marine reptile has finally been revealed after experts discovered that some of its remains actually belonged to fish.

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Geobiologists reported a 550 million-year-old sea sponge that had been missing from the fossil record. The discovery sheds new light on a conundrum that has stumped zoologists and paleontologists for years.

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Researchers invented a technique that allows them to observe which genes and enhancers are active in a cell at the same time. This could help them determine which enhancers control which genes and may reveal potential new drug targets for genetic disorders.

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A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.

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Maternal obesity impacts the eating behaviors of offspring via long-term overexpression of the microRNA miR-505-5p, according to a new study.

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A team of palaeontologists has discovered a fossil of a gigantic flying reptile from the Jurassic period with an estimated wingspan of more than three metres -- making it one of the largest pterosaurs ever found from that era.

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Under certain conditions, some algae are able to produce hydrogen -- a much sought-after green energy source. Its production takes place in the unique catalytic center of the unicellular algae and is only possible if certain cofactors of the relevant proteins are present. Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in the final steps of assembly.

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Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.

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This fossil looks like a lumpy, rounded rock with a couple of exposed teeth that are a little worse for wear, having been submerged and tumbled along the floor of the Gulf of Mexico for thousands of years before washing up on a beach. But when it was X-rayed a doctoral student saw there was more to the fossil that met the eye: a hidden canine tooth that had not yet erupted from the jaw bone. It was just what researchers needed to identify the fossil as belonging to a Homotherium, a genus of large cat that roamed much of the Earth for millions of years.

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Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.