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Categories: Biology: Molecular, Paleontology: Fossils
Published Ancient DNA reveals the appearance of a 6th century Chinese emperor



What did an ancient Chinese emperor from 1,500 years ago look like? A team of researchers reconstructed the face of Chinese Emperor Wu of Northern Zhou using DNA extracted from his remains. The study suggests the emperor's death at the age of 36 might be linked to a stroke. It also sheds light on the origin and migration patterns of a nomadic empire that once ruled parts of northeastern Asia.
Published Connecting the dots to shape growth forces



Branching patterns are prevalent in our natural environment and the human body, such as in the lungs and kidneys. For example, specific genes that express growth factor proteins are known to influence the development of the lungs' complex branches. Researchers have unveiled a regulatory system linking signal, force, and shape in mouse lung structure development. The team recognized that the signal protein ERK plays an active role in causing growing lung tissue to curve.
Published New technique for predicting protein dynamics may prove big breakthrough for drug discovery



Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions.
Published Researchers show that introduced tardigrade proteins can slow metabolism in human cells



Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.
Published Discovery of amino acid unveils how light makes plants open



Scientists have uncovered a unique mechanism that regulates the opening of stomata in plants. Phosphorylation of the amino acid Thr881 on the plasma membrane proton pump plays a key role in this process. The study paves the way for the targeted manipulation of plant physiology, with potential applications in agriculture and environmental sustainability.
Published Natural recycling at the origin of life



How was complex life able to develop on the inhospitable early Earth? At the beginning there must have been ribonucleic acid (RNA) to carry the first genetic information. To build up complexity in their sequences, these biomolecules need to release water. On the early Earth, which was largely covered in seawater, that was not so easy to do.
Published Research uncovers a rare resin fossil find: A spider that aspires to be an ant



Spiders that disguise themselves as ants live in many locations around the globe but until now most had been able to avoid detection from fossil researchers as well as predators.
Published Rays were more diverse 150 million years ago than previously thought



Scientists have explored the puzzling world of rays that lived 150 million years ago and discovered a previously hidden diversity -- including a new ray species. This study significantly expands the understanding of these ancient cartilaginous fish and provides further insights into a past marine ecosystem.
Published New geological study: Scandinavia was born in Greenland



The oldest Scandinavian bedrock was 'born' in Greenland, according to a new geological study. The study helps us understand the origin of continents and why Earth is the only planet in our solar system with life.
Published As we age, our cells are less likely to express longer genes



Aging may be less about specific 'aging genes' and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers. A decline in the expression of long genes with age has been observed in a wide range of animals, from worms to humans, in various human cell and tissue types, and also in individuals with neurodegenerative disease. Mouse experiments show that the phenomenon can be mitigated via known anti-aging factors, including dietary restriction.
Published Researchers name prehistoric amphibian ancestor discovered in Smithsonian collection after Kermit the Frog



Scientists have uncovered the fossilized skull of a 270-million-year-old ancient amphibian ancestor in the collection of the Smithsonian's National Museum of Natural History. The team of researchers described the fossil as a new species of proto-amphibian, which they named Kermitops gratus in honor of the iconic Muppet, Kermit the Frog.
Published Natural molecule found in coffee and human body increases NAD+ levels, improves muscle function during aging



A research consortium made a recent discovery that the natural molecule trigonelline present in coffee, fenugreek, and also in the human body, can help to improve muscle health and function.
Published Decoding the plant world's complex biochemical communication networks



A research team has begun translating the complex molecular language of petunias. Their grammar and vocabulary are well hidden, however, within the countless proteins and other compounds that fill floral cells. Being rooted to the ground, plants can't run away from insects, pathogens or other threats to their survival. But plant scientists have long known that they do send warnings to each other via scent chemicals called volatile organic compounds.
Published Ancient giant dolphin discovered in the Amazon



Measuring between 3 to 3.5 meters, 16 million years old: Paleontologists have announced the discovery of a new species of freshwater dolphin in the Peruvian Amazon region. Surprisingly, its closest living relatives can be found in the river dolphins of South Asia.
Published New archive of ancient human brains challenges misconceptions of soft tissue preservation



A new study has challenged previously held views that brain preservation in the archaeological record is extremely rare. The team compiled a new archive of preserved human brains, which highlighted that nervous tissues actually persist in much greater abundances than traditionally thought, assisted by conditions that prevent decay.
Published A protein found in human sweat may protect against Lyme disease



Human sweat contains a protein that may protect against Lyme disease. About one-third of the population carries a genetic variant of this protein that is associated with Lyme disease in genome-wide association studies.
Published Tanks of the Triassic: New crocodile ancestor identified



Dinosaurs get all the glory. But aetosaurs, a heavily armored cousin of modern crocodiles, ruled the world before dinosaurs did. These tanks of the Triassic came in a variety of shapes and sizes before going extinct around 200 million years ago. Today, their fossils are found on every continent except Antarctica and Australia.
Published How cells are ahead of the curve



The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.
Published Engineers measure pH in cell condensates



In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.
Published Machine learning classifier accelerates the development of cellular immunotherapies



Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.