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Categories: Biology: Molecular, Paleontology: Fossils

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Antiretroviral therapy (ART) does an excellent job at suppressing HIV to undetectable levels in the blood. However, small amounts of latent virus hide throughout the body, and when treatment is stopped, it opens the door for the virus to rebound. Researchers identified which tissues SIV, the nonhuman primate version of HIV, reemerges from first, just seven days after ART is stopped.

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UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers. UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers.

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DNA from ancient feces can offer archaeologists new clues about the life and health of Japanese people who lived thousands of years ago, according to a new study.

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The brown bear is one of the largest living terrestrial carnivores, and is widely distributed across the Northern Hemisphere. Unlike many other large carnivores that went extinct at the end of the last Ice Age (cave bear, sabretoothed cats, cave hyena), the brown bear is one of the lucky survivors that made it through to the present. The question has puzzled biologists for close to a century -- how was this so?

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Scientists have experimental evidence that the key step in protein formation can occur in droplets of pure water.

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Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation.

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Microorganisms were the first forms of life on our planet. The clues are written in 3.5 billion-year-old rocks by geochemical and morphological traces, such as chemical compounds or structures that these organisms left behind. However, it is still not clear when and where life originated on Earth and when a diversity of species developed in these early microbial communities. Evidence is scarce and often disputed. Now, researchers have uncovered key findings about the earliest forms of life. In rock samples from South Africa, they found evidence dating to around 3.42 billion years ago of an unprecedentedly diverse carbon cycle involving various microorganisms. This research shows that complex microbial communities already existed in the ecosystems during the Palaeoarchaean period.

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Reactive oxygen species (ROS), though generally regarded as toxic byproducts of biological processes, serve many important functions in plants. However, the precise mechanism that plants use to regulate the production of ROS remains elusive. In a recent study, researchers clarified how an important ROS-generating enzyme is activated, revealing mechanisms likely conserved across all land plants. Their findings could pave the way for breakthroughs in agricultural and environmental remediation tools.

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Of all the organisms that photosynthesize, land plants have the most complex form. How did this morphology emerge? A team of scientists has taken a deep dive into the evolutionary history of morphological complexity in streptophytes, which include land plants and many green algae. Their research allowed them to go back in time to investigate lineages that emerged long before land plants existed.

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In a world where the intricacies of molecular biology often seem as vast and mysterious as the cosmos, a new groundbreaking study delves into the microscopic universe of proteins, unveiling a fascinating aspect of their existence. This revelation could hold profound implications for the understanding and treatment of a myriad of human diseases.

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By tightly regulating nitrogen uptake, microorganisms avoid overeating nitrogen and thus wasting energy. Scientists now reveal how some methanogenic archaea manage to do so.

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Gliding winged-reptiles were amongst the ancient crocodile residents of the Mendip Hills in Somerset, England, researchers at the have revealed.

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A new study shows the Megalodon, a gigantic shark that went extinct 3.6 million years ago, was more slender than earlier studies suggested. This finding changes scientists' understanding of Megalodon behavior, ancient ocean life, and why the sharks went extinct.

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You suddenly feel sick -- pathogenic bacteria have managed to colonize and spread in your body! The weapons they use for their invasion are harmful toxins that target the host's defense mechanisms and vital cell functions. Before these deadly toxins can attack host cells, bacteria must first export them from their production site -- the cytoplasm -- using dedicated secretion systems.

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Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.

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The new theoretical research proposes that animal size over time depends on two key ecological factors.

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The cell nucleus is considered to be the control center of vital cellular processes, but its material properties continue to puzzle scientists. An international research team has now developed a new technique that provides a previously unattainable view of the mechanical properties inside this control center. For the first time, it has been possible to visualize over time its peculiar dynamic structural features in living cells, which appear to be crucial for cell function.

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Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.

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To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.

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A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.