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Categories: Biology: Molecular, Paleontology: Fossils
Published The extinction of the giant ape: Long-standing mystery solved
(via sciencedaily.com) Original source The largest ever primate Gigantopithecus blacki went extinct when other Asian great apes were thriving, and its demise has long been a mystery. A massive regional study of 22 caves in southern China explores a species on the brink of extinction between 295,000 and 215,000 years ago. As the environment became more seasonal, forest plant communities changed Primates such as orangutans adapted their eating habits and behaviors in response but G. blacki showed signs of stress, struggled to adapt and their numbers dwindled.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne
(via sciencedaily.com) Original source An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Large-scale mapping of pig genes could pave the way for new human medicines
(via sciencedaily.com) Original source Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.
Published Life span increases in mice when specific brain cells are activated
(via sciencedaily.com) Original source A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.
Published Researchers discover molecular 'barcode' used by bacteria to secrete toxins
(via sciencedaily.com) Original source Researchers have discovered a molecular 'barcode' system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
Published Important membrane transport mechanism in pathogenic bacteria
(via sciencedaily.com) Original source Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane. Like a forklift, a soluble protein outside the bacterium transports the substance to the 'elevator' and unloads its cargo there. The freight elevator transports it to the inside of the cell, in other words to another floor.
Published The evolution of photosynthesis better documented thanks to the discovery of the oldest thylakoids in fossil cyanobacteria
(via sciencedaily.com) Original source Researchers have identified microstructures in fossil cells that are 1.75 billion years old. These structures, called thylakoid membranes, are the oldest ever discovered. They push back the fossil record of thylakoids by 1.2 billion years and provide new information on the evolution of cyanobacteria which played a crucial role in the accumulation of oxygen on the early Earth.
Published New roles for autophagy genes in cellular waste management and aging
(via sciencedaily.com) Original source Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins -- and ultimately affect aging.
Published The surprisingly resourceful ways bacteria thrive in the human gut
(via sciencedaily.com) Original source New research shows that some groups of bacteria in the gut are amazingly resourceful, with a large repertoire of genes that help them generate energy for themselves and potentially influence human health as well.
Published Scientists solve mystery of how predatory bacteria recognizes prey
(via sciencedaily.com) Original source A decades-old mystery of how natural antimicrobial predatory bacteria are able to recognize and kill other bacteria may have been solved, according to new research.
Published Nematode proteins shed light on infertility
(via sciencedaily.com) Original source Biologists developed a method for illuminating the intricate interactions of the synaptonemal complex in the nematode C. elegans. The authors identified a trio of protein segments that guide chromosomal interactions, and pinpointed the location where they interact with each other. Their novel method uses a technique known as genetic suppressor screening, which can serve as a blueprint for research on large cellular assemblies that resist traditional structural analysis.
Published 'Giant' predator worms more than half a billion years old discovered in North Greenland
(via sciencedaily.com) Original source Fossils of a new group of animal predators have been located in the Early Cambrian Sirius Passet fossil locality in North Greenland. These large worms may be some of the earliest carnivorous animals to have colonized the water column more than 518 million years ago, revealing a past dynasty of predators that scientists didn't know existed.
Published Study reveals clues to how Eastern equine encephalitis virus invades brain cells
(via sciencedaily.com) Original source Researchers have determined how Eastern equine encephalitis virus attaches to a receptor it uses to enter and infect cells. The findings laid the groundwork for a receptor decoy molecule that protects mice from encephalitis caused by the virus.
Published Bacteria load their syringes
(via sciencedaily.com) Original source Many bacterial pathogens use small injection apparatuses to manipulate the cells of their hosts, such as humans, so that they can spread throughout the body. To do this, they need to fill their syringes with the relevant injection agent. A technique that tracks the individual movement of proteins revealed how bacteria accomplish this challenging task.
Published New reasons eating less fat should be one of your resolutions
(via sciencedaily.com) Original source A new study to motivate your New Year's resolutions: it demonstrates that high-fat diets negatively impact genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system and brain function.
Published 'Juvenile T. rex' fossils are a distinct species of small tyrannosaur
(via sciencedaily.com) Original source A new analysis of fossils believed to be juveniles of T. rex now shows they were adults of a small tyrannosaur, with narrower jaws, longer legs, and bigger arms than T. rex. The species, Nanotyrannus lancensis, was first named decades ago but later reinterpreted as a young T. rex. The new study shows Nanotyrannus was a smaller, longer-armed relative of T. rex, with a narrower snout.
Published Elusive cytonemes guide neural development, provide signaling 'express route'
(via sciencedaily.com) Original source Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning.
Published First step towards synthetic CO2 fixation in living cells
(via sciencedaily.com) Original source Three modules forming a new-to-nature CO2 fixation cycle have been successfully implemented in E.coli.
Published Big impacts from small changes in cell
(via sciencedaily.com) Original source Tiny things matter -- for instance, one amino acid can completely alter the architecture of the cell. Researchers have now investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin. Actin is found in all living cells where it has a range of important functions -- from muscle contraction to cell signalling and cell shape. This protein comes in two different varieties termed 'isoforms', which are known as gamma actin and beta actin.
Published How jellyfish regenerate functional tentacles in days
(via sciencedaily.com) Original source At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -- but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage. Jellyfish, along with other cnidarians such as corals and sea anemones, exhibit high regeneration abilities, but how they form the critical blastema has remained a mystery until now.