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Categories: Biology: Molecular, Paleontology: Fossils
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells
(via sciencedaily.com) Original source Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published First mice engineered to survive COVID-19 like young, healthy humans
(via sciencedaily.com) Original source Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published How the fish got its shoulder
(via sciencedaily.com) Original source A new analysis of the bones and muscles in ancient fish gives new clues about how the shoulder evolved in animals -- including us.
Published Plastic-eating bacteria turn waste into useful starting materials for other products
(via sciencedaily.com) Original source Mountains of used plastic bottles get thrown away every day, but microbes could potentially tackle this problem. Now, researchers report that they've developed a plastic-eating E. coli that can efficiently turn polyethylene terephthalate (PET) waste into adipic acid, which is used to make nylon materials, drugs and fragrances.
Published New species of mosasaur named for Norse sea serpent
(via sciencedaily.com) Original source Scientists have discovered a new species of mosasaur, large, carnivorous aquatic lizards that lived during the late Cretaceous. With 'transitional' traits that place it between two well-known mosasaurs, the new species is named after a sea serpent in Norse mythology, Jormungandr, and the small North Dakota city Walhalla near to where the fossil was found.
Published Scientists create special 'telomouse' with human-like telomeres
(via sciencedaily.com) Original source Researchers introduce the 'Telomouse'. By making a subtle genetic alteration in standard lab mice, they've made the mouse telomeres, which protect the chromosome ends, more closely resemble those in humans. The Telomouse model, developed by incorporating a genetic variation from a mouse species with naturally shorter telomeres, provides a valuable resource for in-depth aging and cancer research. This discovery promises to reveal new insights into the genetics of aging and may contribute to enhanced longevity and well-being.
Published Intestinal bacteria metabolite promotes capture of antigens by dendritic cells
(via sciencedaily.com) Original source Dendritic cells are immune cells that capture and present antigens to T cells, activating an immune response. Researchers have discovered that short-chain fatty acids produced by intestinal bacteria regulate a crucial step in this process, the extension of dendritic 'arms.' This breakthrough finding could potentially lead to the development of disease prevention strategies involving beneficial bacteria and new drugs targeting the regulation of dendritic cell function.
Published Controlling organoids with light
(via sciencedaily.com) Original source Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.
Published Protein root discovery seals future of climate-proof plants
(via sciencedaily.com) Original source Researchers have discovered a protein that seals plant roots to regulate the uptake of nutrients and water from the soil, the discovery could help develop climate proof crops that require less water and chemical fertilizers.
Published Researchers solve protein mystery
(via sciencedaily.com) Original source Researchers have uncovered that proteins use a common chemical label as a shield to protect them from degradation, which in turn affects motility and aging.
Published Genetic methods enable the use of fossil lipids as biomarkers for oxygen-producing primordial bacteria
(via sciencedaily.com) Original source Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems. For a long time, a certain type of fossil lipid, so-called 2-methylhopanes, was considered to be an important biomarker for Cyanobacteria in sediments, some of which are hundreds of millions of years old. However, this came into doubt when it turned out that not only Cyanobacteria but also Alphaproteobacteria are genetically capable of producing these lipids.
Published Mammalian cells may consume bacteria-killing viruses to promote cellular health
(via sciencedaily.com) Original source Bacteriophages, also called phages, are viruses that infect and kill bacteria, their natural hosts. But from a macromolecular viewpoint, phages can be viewed as nutritionally enriched packets of nucleotides wrapped in an amino acid shell. A study suggests that mammalian cells internalize phages as a resource to promote cellular growth and survival.
Published Membrane transporter ensures mobility of sperm cells
(via sciencedaily.com) Original source Special proteins -- known as membrane transporters -- are key to the mobility of sperm cells. A research team has, with the aid of cryo-electron microscopy, succeeded in decoding the structure of such a transporter and its mechanism. These findings will enable a better understanding of the molecular foundations of reproductive capacity and could, in the long term, contribute to developing new approaches to treating fertility disorders and new methods of specific contraception.
Published Climate change likely impacted human populations in the Neolithic and Bronze Age
(via sciencedaily.com) Original source Human populations in Neolithic Europe fluctuated with changing climates, according to a new study.
Published Sediment core analysis supports new epoch characterized by human impact on planet
(via sciencedaily.com) Original source Scientists analyzed open-source data to track vegetation changes across North America since the end of the Pleistocene Epoch, and conclude that humans have had as much of an impact on the landscape as the retreat of the glaciers at the end of the Ice Age.
Published Defect in fruit fly respiratory system may provide insights into human aortic aneurysms
(via sciencedaily.com) Original source A team of researchers has gained new insights into the respiratory system of fruit flies -- the so-called tracheal system -- which could be important for future research into aneurysms. Scientists carried out genetic, cell biological and biochemical studies on Drosophila embryos. They found that the cells in the fruit fly's tracheal system are connected to the extracellular matrix by the proteins Dumpy and Piopio.
Published Bizarre new fossils shed light on ancient plankton
(via sciencedaily.com) Original source Recently discovered microfossils date back half a billion years. Resembling modern-day algae, they provide insight into early life in our oceans.
Published How eggs of the Zika-carrying mosquito survive desiccation
(via sciencedaily.com) Original source Eggs of the mosquito that carries Zika virus can tolerate extended desiccation by altering their metabolism, according to a new study. The finding offers potential new ways to control the spread of this mosquito.
Published Origin of ancient mummified baboons found in Egypt
(via sciencedaily.com) Original source Primatologists are using genetic analysis to determine the geographic origin of ancient mummified baboons found in Egypt. The team finds evidence that the two legendary trading regions of Punt and Adulis may have been the same place separated by a thousand years of history.
Published Discovery finds ferns produce crop-saving insecticide
(via sciencedaily.com) Original source Researchers have solved the structure of a novel insecticidal protein that is effective in protecting major crop plants like corn and soybean from pests and is naturally produced by ferns.