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Categories: Biology: Molecular, Offbeat: Earth and Climate

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Researchers have deciphered the complex interplay of various enzymes around the innate immune receptor toll-like receptor 7 (TLR7), which plays an important role in defending our bodies against viruses.

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A parasite that not only feeds of its host, but also makes the host change its own metabolism and thus biology. Microbiologists have shown this for the very first time in a specific group of parasitic microbes, so-called DPANN archea. Their study shows that these archaea are very 'picky eaters', which might drive their hosts to change the menu.

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Viruses known as 'jumbo' phages are seen as a potential tool against deadly bacterial infections. But scientists must first decipher the extraordinary makeup of these mysterious viruses. Researchers have now uncovered a key piece of jumbo phage development that helps them counter bacteria.

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Scientists are harnessing cells to make new types of materials that can grow, repair themselves and even respond to their environment. These solid 'engineered living materials' are made by embedding cells in an inanimate matrix that's formed in a desired shape. Now, researchers have 3D printed a bioink containing plant cells that were then genetically modified, producing programmable materials. Applications could someday include biomanufacturing and sustainable construction.

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Conventional plant regeneration approaches by cell culture require the external application of plant growth regulators, including hormones. However, optimizing culture conditions can be laborious. Now, researchers have developed a novel plant regeneration system that omits the need for hormone application by genetically regulating the expression of genes that control plant cell differentiation. Their work holds significant potential in the development of genetically modified plants in a simpler and cost-effective manner.

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Researchers have discovered a new mechanism of oil biosynthesis and found a way to genetically engineer a type of test plant to more efficiently produce different kinds of seed oil that it otherwise wouldn't make. While the engineering is proof-of-concept, this discovery could lead to improved production of valuable oils used in food and by a range of industries. The modified plant overcame metabolic bottlenecks and produced significant amounts of an oil similar to castor oil that it doesn't naturally produce.

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Scientists have applied a data-driven approach to understanding firefly population dynamics on a continental scale. Key findings from this new study indicate that fireflies, part of the beetle order, are sensitive to various environmental factors, from short-term weather conditions to longer climatic trends, including the number of growing-degree days related to temperature accumulations.

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The research explores how CRISPR can be used to edit RNA.

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Greening the way we eat needn't mean going vegetarian. A healthy, more realistic solution is to adopt a flexitarian diet where seafoods add umami to 'boring' vegetables. A gastrophysicist puts mathematical equations to work in calculating the umami potential of everything from seaweed and shrimp paste to mussels and mackerel.

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Researchers report on the molecular assembly of one of the most common anti-phage systems -- from the family of proteins called Gabija -- that is estimated to be used by at least 8.5%, and up to 18%, of all bacteria species on Earth.

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Using environmental DNA analysis, an international team of researchers identified a collection of plants used in ceremonial rituals in the ancient Maya city of Yaxnohcah in Mexico. The plants, known for their religious associations and medicinal properties, were discovered beneath a plaza floor where a ballcourt was built.

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What happens in the body when we are hungry and see and smell food? A team of researchers has now been able to show in mice that adaptations in the liver mitochondria take place after only a few minutes. Stimulated by the activation of a group of nerve cells in the brain, the mitochondria of the liver cells change and prepare the liver for the adaptation of the sugar metabolism. The findings could open up new avenues for the treatment of type 2 diabetes.

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How do birds fly in a coordinated and seemingly effortless fashion? Part of the answer lies in precise, and previously unknown, aerodynamic interactions, reports a team of mathematicians. Its breakthrough broadens our understanding of wildlife, including fish, who move in schools, and could have applications in transportation and energy.

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Researchers have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for researchers worldwide to increase knowledge about human health and disease.

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Conditions such as diabetes, heart attack and vascular diseases commonly diagnosed in people with spinal cord injuries can be traced to abnormal post-injury neuronal activity that causes abdominal fat tissue compounds to leak and pool in the liver and other organs, a new animal study has found.

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Cells constantly navigate a dynamic environment, facing ever-changing conditions and challenges. But how do cells swiftly adapt to these environmental fluctuations? A new study is answering that question by challenging our understanding of how cells function. A team of researchers suggests that cells possess a previously unknown information processing system that allows them to make rapid decisions independent of their genes.

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Researchers have made a breakthrough for evolutionary biology of the Solanaceae family, which includes peppers, potatoes and petunias.

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Every cuckoo is an adopted child -- raised by foster parents, into whose nest the cuckoo mother smuggled her egg. The cuckoo mother is aided in this subterfuge by her resemblance to a bird of prey. There are two variants of female cuckoos: a gray morph that looks like a sparrowhawk, and a rufous morph. Male cuckoos are always gray.

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The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells -- the cells that have a specialized function, like skin and muscle cells -- they remain elusive in the first cells of our bodies, the embryonic cells. Embryonic mitosis is notoriously difficult to study in vertebrates, as live functional analyses and -imaging of experimental embryos are technically limited, which makes it hard to track cells during embryogenesis.

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The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers have now discovered viruses that infect this harmful microbe. Named Naegleriavirus, these belong to the giant viruses, a group known for their unusually large particles and complex genomes.