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Categories: Biology: Molecular, Offbeat: Earth and Climate

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Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Machine learning classifier accelerates the development of cellular immunotherapies      (via sciencedaily.com)     Original source 

Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.

Biology: Biochemistry Biology: Cell Biology Biology: Molecular
Published

Small amounts of licorice raise blood pressure, study finds      (via sciencedaily.com)     Original source 

It is known that large amounts of licorice cause high blood pressure. A new study now shows that even small amounts of licorice raise blood pressure. The individuals who react most strongly also show signs of strain on the heart.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Environmental: General Geoscience: Geochemistry Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

It's hearty, it's meaty, it's mold      (via sciencedaily.com)     Original source 

Scientists are exploring how tuning the genomes of mushrooms and molds can transform these food sources into gourmet, nutrient-packed meals made with minimal processing and a light environmental footprint.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular
Published

Alzheimer's drug fermented with help from AI and bacteria moves closer to reality      (via sciencedaily.com)     Original source 

Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

New bioengineered protein design shows promise in fighting COVID-19      (via sciencedaily.com)     Original source 

A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Molecular Biology: Zoology Ecology: Animals
Published

Sleep-wake rhythm: Fish change our understanding of sleep regulation      (via sciencedaily.com)     Original source 

Researchers have discovered that some fish -- unlike humans -- do not need orexin to stay awake. This molecule was thought to be necessary for normal wake and sleep rhythms in vertebrates. Humans without orexin suffer from narcolepsy.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: Genetics Biology: Molecular
Published

New discovery reveals how the egg controls sperm entry      (via sciencedaily.com)     Original source 

After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Even cells know the importance of recycling      (via sciencedaily.com)     Original source 

Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Environmental: Water Geoscience: Earth Science Geoscience: Geochemistry Geoscience: Geology
Published

Sulfur and the origin of life      (via sciencedaily.com)     Original source 

A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.

Geoscience: Earthquakes Offbeat: Earth and Climate Offbeat: General Physics: Acoustics and Ultrasound
Published

What kinds of seismic signals did Swifties send at LA concert?      (via sciencedaily.com)     Original source 

Seattle may have experienced its own Swift Quake last July, but at an August 2023 concert Taylor Swift's fans in Los Angeles gave scientists a lot of shaking to ponder. After some debate, a research team concluded that it was likely the dancing and jumping motions of the audience at SoFi Stadium -- not the musical beats or reverberations of the sound system -- that generated the concert's distinct harmonic tremors.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Tryptophan in diet, gut bacteria protect against E. coli infection      (via sciencedaily.com)     Original source 

Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

New computational strategy boosts the ability of drug designers to target proteins inside the membrane      (via sciencedaily.com)     Original source 

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.

Biology: Biochemistry Biology: Marine Ecology: Animals Ecology: Extinction Ecology: Sea Life Environmental: Ecosystems Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

Sonic youth: Healthy reef sounds increase coral settlement      (via sciencedaily.com)     Original source 

Healthy coral reefs have rich soundscapes, full of the croaks, purrs, and grunts of various fishes and the crackling of snapping shrimp. Larval coral uses these sounds as cues to identify the best places to settle and grow. The authors found that sound could potentially be a vital tool in the effort to restore coral reefs. Broadcasting the sounds of a healthy reef to a reef that is degraded encourages coral larvae to settle there. This indicates that it's possible that 'acoustic enrichment' can be a key intervention to support imperiled reefs.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Milk to the rescue for diabetics? Cow produces human insulin in milk      (via sciencedaily.com)     Original source 

An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry
Published

A simple and robust experimental process for protein engineering      (via sciencedaily.com)     Original source 

A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Scientists find weak points on Epstein-Barr virus      (via sciencedaily.com)     Original source 

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

How a natural compound from sea squirts combats cancer      (via sciencedaily.com)     Original source 

Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.

Environmental: General Geoscience: Earth Science Geoscience: Geochemistry Geoscience: Geology Offbeat: Earth and Climate Offbeat: General Offbeat: Space Space: Exploration Space: General Space: The Solar System
Published

Scientists propose new theory that explains sand ripples on Mars and on Earth      (via sciencedaily.com)     Original source 

Sand ripples are symmetrical. Yet wind -- which causes them -- is very much not. Furthermore, sand ripples can be found on Mars and on Earth. They would be even more fascinating if the same effect found on Mars could be found here on Earth as well. What if one unified theory could explain their formation on both planets?