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Categories: Biology: Molecular, Offbeat: Earth and Climate
Published Researchers decipher new molecular mechanisms related to biological tissue regeneration
(via sciencedaily.com) Original source A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease and several types of cancer.
Published Lampreys possess a 'jaw-dropping' evolutionary origin
(via sciencedaily.com) Original source Lampreys are one of only two living jawless vertebrates Jaws are formed by a key stem cell population called the neural crest New research reveals the gene regulatory changes that may explain morphological differences between jawed and jawless vertebrates.
Published New drug shows promise in clearing HIV from brain
(via sciencedaily.com) Original source An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.
Published Climate change will bring more turbulence to flights in the Northern Hemisphere, study finds
(via sciencedaily.com) Original source A type of invisible, unpredictable air turbulence is expected to occur more frequently in the Northern Hemisphere as the climate warms. Known as clear air turbulence, the phenomenon also increased in the Northern Hemisphere between 1980 and 2021.
Published A recipe for zero-emissions fuel: Soda cans, seawater, and caffeine
(via sciencedaily.com) Original source Engineers discovered that when the aluminum in soda cans is purified and mixed with seawater, the solution produces hydrogen -- which can power an engine or fuel cell without generating carbon emissions. The reaction can be sped up by adding caffeine.
Published The ocean is becoming too loud for oysters, research finds
(via sciencedaily.com) Original source Baby oysters rely on natural acoustic cues to settle in specific environments, but new research reveals that noise from human activity is interfering with this critical process.
Published Whale shark tracked for record-breaking four years
(via sciencedaily.com) Original source Researchers have been tracking a 26-foot endangered whale shark -- named 'Rio Lady' -- with a satellite transmitter for more than four years -- a record for whale sharks and one of the longest tracking endeavors for any species of shark.
Published Research sheds light on the role of PTPRK in tissue repair and cancer
(via sciencedaily.com) Original source New research has advanced our knowledge of multiple roles for PTPRK, a receptor tyrosine phosphatase linked to the regulation of cell-cell adhesion, growth factor signalling and tumor suppression. Through a characterization of the function of PTPRK in human cell lines and mice, the team distinguished catalytic and non-catalytic functions of PTPRK. The findings extend what is known about the signalling mechanisms involving PTPRK as a phosphatase and its role in colorectal health but also shed new light on the extent of its function via non-catalytic signalling mechanisms.
Published Under pressure: How cells respond to physical stress
(via sciencedaily.com) Original source Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists have used cryo-electron microscopy to observe how lipids and proteins at the plasma membrane interact and react to mechanical stress. This work shows that, depending on conditions, small membrane regions can stabilize various lipids to trigger specific cellular responses. These discoveries confirm the existence of well-organized lipid domains and begin to reveal the role they play in cell survival.
Published Eyes for Love: Searching for light and a mate in the deep, dark sea, male dragonfishes grow larger eyes than the females they seek
(via sciencedaily.com) Original source The eyes of the male dragonfish grow larger for mate seeking, a sexual dimorphism that makes the dragonfish an anomaly in vertebrate evolution, researchers report.
Published Dual action antibiotic could make bacterial resistance nearly impossible
(via sciencedaily.com) Original source New drug that disrupts two cellular targets would make it much harder for bacteria to evolve resistance.
Published New rapid method for determining virus infectivity
(via sciencedaily.com) Original source A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionize the response to future pandemics, researchers report.
Published Fruit fly post-mating behavior controlled by male-derived peptide via command neurons, study finds
(via sciencedaily.com) Original source Scientists have succeeded in pinpointing the neurons within a female fruit fly's brain that respond to signals from the male during mating.
Published Exposing dengue's invasion strategies
(via sciencedaily.com) Original source Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease. Now, research uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts, with the potential to aid in developing novel antiviral treatments and vaccines.
Published Not everything that tastes bitter is potentially harmful: But why? Study provides an explanation
(via sciencedaily.com) Original source A bitter taste is traditionally considered a warning sign of potentially toxic substances. But not all bitter substances are harmful. For example, some peptides and free amino acids taste bitter, even though they are non-toxic, nutritious and sometimes even vital for humans. A new study now offers an explanation for this seemingly paradoxical phenomenon.
Published Transient structure in fly leg holds clue to insect shape formation
(via sciencedaily.com) Original source A little leg may reveal something big about how closely related insect species can drastically differ in body shape, according to a new study. The team imaged live cells of fruit flies in the last stages of development over several days and found a new structure that appears to help guide a section of the leg into its final shape.
Published Secrets behind viral precision
(via sciencedaily.com) Original source New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.
Published Paleolithic diets are not without risks
(via sciencedaily.com) Original source High-protein diets, known as 'Paleolithic diets', are popular. Using mouse models, scientists have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks. Excess protein greatly increases ammonium production, overwhelming the liver. Excess ammonium can cause neurological disorders and, in severe cases, lead to coma. These results suggest caution when following these diets.
Published Smart soil can water and feed itself
(via sciencedaily.com) Original source A newly engineered type of soil can capture water out of thin air to keep plants hydrated and manage controlled release of fertilizer for a constant supply of nutrients.
Published Genome recording makes living cells their own historians
(via sciencedaily.com) Original source Genomes can now be used to store information about a variety of transient biological events inside of living cells, as they happen, like a flight recorder collecting data from an aircraft. The method, called ENGRAM, aims to turn cells into their own historians. ENGRAM couples each kind of biological signal or event inside a cell to a symbolic barcode. This new strategy traces and archives the type and timing of biological signals inside the cell by inserting this information into the genome. For example, this record-keeping can track the commands that turn genes on or off.