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Categories: Biology: General, Biology: Marine
Published Innovative antiviral defense with new CRISPR tool



The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.
Published Oceanographers uncover the vital role of mixing down of oxygen in sustaining deep sea health



Oceanographers have shown for the first time the important role of the 'mixing down' of oxygen in maintaining healthy conditions in the deep waters.
Published Researchers identify new genetic risk factors for persistent HPV infections



Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide. While the immune system usually clears HPV infections, those that persist can lead to cancer, and a new finding suggests that certain women may have a genetic susceptibility for persistent or frequent HPV infections. These genetic variants could raise a woman's risk of getting cervical cancer from a high-risk HPV infection.
Published First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle



Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.
Published New approach for combating 'resting' bacteria



Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.
Published Tropical coral-infecting parasites discovered in cold marine ecosystems



Parasites thought only to infect tropical coral reefs have been discovered in a large variety of creatures in cold marine ecosystems along the Northeast Pacific, according to new research.
Published Oxidant pollutant ozone removes mating barriers between fly species



Researchers show that ozone levels, such as those found in many places on hot summer days today, destroy the sex pheromones of fruit fly species. As a result, some natural mating boundaries maintained by species-specific pheromones no longer exist. The research team has shown in experiments that flies of different species mate when exposed to ozone and produce hybrid offspring. Since most of these offspring are unable to reproduce, the results could provide another explanation for the global decline of insects.
Published Genetic underpinnings of environmental stress identified in model plant



Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.
Published Geobiology: New placozoan habitat discovered



Traces of DNA in the stomachs of predatory snails give a team og geobiologists new insights into the ecology of placozoans.
Published Ants in Colorado are on the move due to climate change



Ant species living in Boulder's foothills have shifted their habitat over the last six decades, potentially affecting local ecosystems, suggests a new study.
Published New drug prevents flu-related inflammation and lung damage



Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.
Published The genesis of our cellular skeleton, image by image



Cells contain various specialized structures -- such as the nucleus, mitochondria or peroxisomes -- known as 'organelles'. Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction.
Published Researchers discover how we perceive bitter taste



A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.
Published 3D mouth of an ancient jawless fish suggests they were filter-feeders, not scavengers or hunters



Early jawless fish were likely to have used bony projections surrounding their mouths to modify the mouth's shape while they collected food. Experts have used CT scanning techniques to build up the first 3D pictures of these creatures, which are some of the earliest vertebrates (animals with backbones) in which the mouth is fossilized. Their aim was to answer questions about feeding in early vertebrates without jaws in the early Devonian epoch -- sometimes called the Age of Fishes -- around 400 million years ago.
Published Scientists identify pro-aging 'sugar signature' in the blood of people living with HIV



Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV.
Published Cockayne syndrome: New insights into cellular DNA repair mechanism



Researchers decode repair mechanism during transcription of genetic information.
Published Deforestation harms biodiversity of the Amazon's perfume-loving orchid bees



A survey of orchid bees in the Brazilian Amazon, carried out in the 1990s, is shedding new light the impact of deforestation on the scent-collecting pollinators, which some view as bellwethers of biodiversity in the neotropics.
Published Cold-affinity algae species are gradually being replaced by warm-affinity ones off the coast of Biscay



A study has analyzed the impact of the rise in sea surface temperature on macroalgae communities over the last four decades. Points at various depths were investigated in a location off the coast of Biscay, and an increasing scarcity was observed in the number of cold-affinity structuring species, while small warm-affinity ones have proliferated. The researchers are warning that some ecological functions are in jeopardy as a result.
Published A microbial plastic factory for high-quality green plastic



Engineered bacteria can produce a plastic modifier that makes renewably sourced plastic more processable, more fracture resistant and highly biodegradable even in sea water. The development provides a platform for the industrial-scale, tunable production of a material that holds great potential for turning the plastic industry green.
Published What's quieter than a fish? A school of them



Swimming in schools makes fish surprisingly stealthy underwater, with a group able to sound like a single fish. Engineers working with a high-tech simulation of schooling mackerel offer new insight into why fish swim in schools and promise for the design and operation of much quieter submarines and autonomous undersea vehicles.