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Categories: Biology: Marine, Biology: Molecular
Published Yeast cells can produce drugs for treatment of psychotic disorders
(via sciencedaily.com) Original source An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.
Published Team creates synthetic enzymes to unravel molecular mysteries
(via sciencedaily.com) Original source A bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos. The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed. By learning the molecular rules of signal formation in a developing animal, researchers aim to engineer mechanisms -- such as giving cells new instructions -- that could play a role in treating or preventing disease.
Published Scientists use quantum biology, AI to sharpen genome editing tool
(via sciencedaily.com) Original source Scientists used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.
Published Barnacle bends shape to fend off warm-water sea snails on the move
(via sciencedaily.com) Original source Some barnacles are 'morphing' to protect themselves from predatory warm-water sea snails, which are expanding into their territory due to climate change.
Published First live birth of a chimeric monkey using embryonic stem cell lines
(via sciencedaily.com) Original source A team of researchers has reported for the first time the live birth of a monkey that contains a high proportion of cells derived from a monkey stem cell line. This 'chimeric' monkey is composed of cells that originate from two genetically distinct embryos of the same species of monkey. This has previously been demonstrated in rats and mice but, until now, has not been possible in other species, including non-human primates.
Published Zooplankton in ocean and freshwater are rapidly escalating the global environmental threat of plastics
(via sciencedaily.com) Original source A collaborative research team has recently revealed that rotifers, a kind of microscopic zooplankton common in both fresh and ocean water around the world, are able to chew apart microplastics, breaking them down into even smaller, and potentially more dangerous, nanoplastics -- or particles smaller than one micron. Each rotifer can create between 348,000 -- 366,000 per day, leading to uncountable swarms of nanoparticles in our environment.
Published Zen and the art of mitochondrial maintenance: The machinery of death makes a healthier life
(via sciencedaily.com) Original source While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or 'healthspan,' that precedes the inevitable decline of advancing age. Researchers have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.
Published Temperature increase triggers viral infection
(via sciencedaily.com) Original source Researchers have mapped on an atomic level what happens in a virus particle when the temperature is raised.
Published A different take on phosphorus: Bacteria use organic phosphorus and release methane in the process
(via sciencedaily.com) Original source Some bacteria are able to tap into unusual sources of nutrients in the surface water of the oceans. This enables them to increase their primary production and extract more carbon dioxide from the atmosphere. In doing so, however, they release the potent greenhouse gas methane.
Published Device 'smells' seawater to discover, detect novel molecules
(via sciencedaily.com) Original source Under the ocean's surface, marine organisms are constantly releasing invisible molecules. Some of the chemical clues reveal which creatures are nearby, while others could be used someday as medications. Now, researchers report a proof-of-concept device that 'sniffs' seawater, trapping dissolved compounds for analyses. The team showed that the system could easily concentrate molecules that are present in underwater caves and holds promise for drug discovery in fragile ecosystems, including coral reefs.
Published Yeast with an over half synthetic genome is created in the lab
(via sciencedaily.com) Original source Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains. A global consortium is working to develop the first synthetic eukaryote genome from scratch. The team has now synthesized and debugged all sixteen yeast chromosomes.
Published Scientists one step closer to re-writing world's first synthetic yeast genome, unravelling the fundamental building blocks of life
(via sciencedaily.com) Original source Scientists have engineered a chromosome entirely from scratch that will contribute to the production of the world's first synthetic yeast.
Published Scientists take major step towards completing the world's first synthetic yeast
(via sciencedaily.com) Original source A team of Scientists has completed construction of a synthetic chromosome as part of a major international project to build the world's first synthetic yeast genome. The work represents completion of one of the 16 chromosomes of the yeast genome, which is part of the biggest project ever in synthetic biology; the international synthetic yeast genome collaboration. The collaboration, known as 'Sc2.0' has been a 15-year project involving teams from around the world (UK, US, China, Singapore, UK, France and Australia), working together to make synthetic versions of all of yeast's chromosomes. Alongside this paper, another 9 publications are also released today from other teams describing their synthetic chromosomes. The final completion of the genome project -- the largest synthetic genome ever -- is expected next year.
Published Why a surprising discovery, warming seas and the demise of the 'Meg' may spell trouble for more and more sharks
(via sciencedaily.com) Original source Some unexpected shark strandings and subsequent surprises following autopsies have, ironically, taken marine biologists millions of years back in time as they look to the future with concern. Adding chapters to an evolutionary tale involving the infamous megalodon shark (the 'Meg'), they think their work suggests there are more warm-blooded sharks out there than previously believed, and -- based on the Meg's demise -- these species may be at great risk from warming seas.
Published Obesity linked to neurodegeneration through insulin resistance
(via sciencedaily.com) Original source Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.
Published 450-million-year-old organism finds new life in Softbotics
(via sciencedaily.com) Original source Researchers have used fossil evidence to engineer a soft robotic replica of pleurocystitids, a marine organism that existed nearly 450 million years ago and is believed to be one of the first echinoderms capable of movement using a muscular stem.
Published New algae species rewrites understanding of reef systems
(via sciencedaily.com) Original source An international team of marine scientists has identified and officially named four species of algae new to science, challenging previous taxonomical assumptions within the Porolithon genus. The discovery has far-reaching implications for our understanding of the ecological role of these algae in the coral reef ecosystem.
Published Two fins are better than one: Fish synchronize tail fins to save energy
(via sciencedaily.com) Original source They say two heads are better than one. But in the world of fish, it appears two fins are better than one. Researchers have produced a theoretical model that demonstrates the underlying mechanisms behind how fish will synchronize their fin movements to ride each other's vortices, thereby saving energy.
Published Crust-forming algae are displacing corals in tropical waters worldwide
(via sciencedaily.com) Original source Over the past few decades, algae have been slowly edging corals out of their native reefs across the globe by blocking sunlight, wearing the corals down physically, and producing harmful chemicals. But in recent years, a new type of algal threat has surfaced in tropical regions like the Caribbean -- one that spreads quickly and forms a crust on top of coral and sponges, suffocating the organisms underneath and preventing them from regrowing. Marine biologists report that peyssonnelioid alga crusts, or PACs, are expanding quickly across reefs worldwide, killing off corals and transforming entire ecosystems.
Published Some benefits of exercise stem from the immune system
(via sciencedaily.com) Original source Research in mice shows that the anti-inflammatory properties of exercise may arise from immune cells mobilized to counter exercise-induced inflammation. Immune cells prevent muscle damage by lowering levels of interferon, a key driver of chronic inflammation, inflammatory diseases, and aging.