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Categories: Biology: Botany, Biology: Molecular

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Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.

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Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.

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Plants and the animals that eat them have evolved together in fascinating ways, creating a dynamic interplay of survival strategies. Many plants have developed physical and chemical defenses to fend off herbivores. A well-known strategy in flowering plants is to produce nectar to attract 'ant bodyguards.' Recent research explores the evolution of this same defense strategy in ferns.

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Research work on symbiosis -- a mutually beneficial relationship between living organisms -- is pushing back against the newer theory of a 'single-origin' of root nodule symbiosis (RNS) -- that all symbiosis between plant root nodules and nitrogen-fixing bacteria stems from one point--instead suggesting a 'multiple-origin' theory of sybiosis which opens a better understanding for genetically engineering crops.

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Researchers recently published findings that could lay the groundwork for applying quantum computing methods to protein structure prediction.

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Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.

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New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.

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A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.

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Researchers involved in cataloguing the world's plant species are hunting for answers as to what makes some groups of plants so successful. One of their major goals is to predict more accurately which lineages of flowering plants -- some of which are of huge importance to people and to ecosystems -- are at a greater risk from global climate change.

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Orchid plants nurture their seedlings via an underground fungal network, new research has revealed.

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Participants following an intermittent fasting and protein-pacing regimen, which involves evenly spaced protein intake throughout the day, saw better gut health, weight loss and metabolic responses. These benefits were notably greater than those seen with simple calorie restriction. The findings could advance our understanding of the relationship between the gut microbiome and metabolism and improve strategies for managing obesity.

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A widely found gene in plants has been newly identified as a key transporter of a hormone that influences the size of corn. The discovery offers plant breeders a new tool to develop desirable dwarf varieties that could enhance the crop's resilience and profitability.

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Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

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Scientists have designed a way to 'cloak' proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.

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Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of genomes in single cells that are too difficult to detect with other methods.

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Plant hydraulics drive the biological process that moves fluids from roots to plant stems and leaves, creating streaming electric potential, or voltage, in the process. A study closely examined the differences in voltage caused by the concentrations of ions, types of ions, and pH of the fluid plants transport, tying the voltage changes to the plant's circadian rhythm that causes adjustments day and night. According to the authors, this consistent, cyclic voltage creation could be harnessed as an energy source.

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Maize is one of the world's most widely grown crops and is essential to global food security. But like other plants, its growth and productivity can be limited by the slow activity of Rubisco, the enzyme responsible for carbon assimilation during photosynthesis. Scientists have now demonstrated a promising approach to enhancing Rubisco production, thus improving photosynthesis and overall plant growth.

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Researchers have developed a new technique to view living mammalian cells. The team used a powerful laser, called a soft X-ray free electron laser, to emit ultrafast pulses of illumination at the speed of femtoseconds, or quadrillionths of a second. With this they could capture images of carbon-based structures in living cells for the first time, before the soft X-ray radiation damaged them.

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In an interdisciplinary study, researchers discovered that symbiotic bacteria communicate with legume plants through specific molecules and that this communication influences which bacteria grow near the plant roots. The findings provide insights into how plants and soil bacteria form beneficial partnerships for nutrient uptake and resilience. These results are a step towards understanding how communication between plants and soil bacteria can lead to specific beneficial associations providing plants with nutrients.

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Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.