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Categories: Biology: Botany, Biology: Molecular
Published How cells are ahead of the curve
(via sciencedaily.com) Original source The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.
Published Cacao plants' defense against toxic cadmium unveiled
(via sciencedaily.com) Original source Researchers used bright X-rays to unveil how cacao trees protect themselves from toxic metal cadmium.
Published Engineers measure pH in cell condensates
(via sciencedaily.com) Original source In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.
Published Why do tree frogs lay their eggs on the ground?
(via sciencedaily.com) Original source A curious aspect of tree frogs is that they often lay their eggs on the ground where the risk of predation by natural enemies is greater than in the trees where they live. A research team suggested that the reason for this behavior is to protect the eggs from low temperatures. Their findings highlight the challenge faced by tree frogs: Should they attempt to maintain an optimal temperature for their eggs or risk predation?
Published Machine learning classifier accelerates the development of cellular immunotherapies
(via sciencedaily.com) Original source Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.
Published Researchers can reveal illegal timber exports
(via sciencedaily.com) Original source A new method of timber analysis can confidently identify the location in which the tree was harvested. The method has been developed with the aim of combating illegal timber imports from Russia and Belarus.
Published Small amounts of licorice raise blood pressure, study finds
(via sciencedaily.com) Original source It is known that large amounts of licorice cause high blood pressure. A new study now shows that even small amounts of licorice raise blood pressure. The individuals who react most strongly also show signs of strain on the heart.
Published Alzheimer's drug fermented with help from AI and bacteria moves closer to reality
(via sciencedaily.com) Original source Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.
Published New bioengineered protein design shows promise in fighting COVID-19
(via sciencedaily.com) Original source A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.
Published Sleep-wake rhythm: Fish change our understanding of sleep regulation
(via sciencedaily.com) Original source Researchers have discovered that some fish -- unlike humans -- do not need orexin to stay awake. This molecule was thought to be necessary for normal wake and sleep rhythms in vertebrates. Humans without orexin suffer from narcolepsy.
Published New discovery reveals how the egg controls sperm entry
(via sciencedaily.com) Original source After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.
Published Even cells know the importance of recycling
(via sciencedaily.com) Original source Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.
Published Sulfur and the origin of life
(via sciencedaily.com) Original source A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.
Published Tryptophan in diet, gut bacteria protect against E. coli infection
(via sciencedaily.com) Original source Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure.
Published New computational strategy boosts the ability of drug designers to target proteins inside the membrane
(via sciencedaily.com) Original source Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.
Published Simple trick could improve accuracy of plant genetics research
(via sciencedaily.com) Original source Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk
(via sciencedaily.com) Original source An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.
Published Summer solstice triggers synchronized beech tree reproduction across Europe
(via sciencedaily.com) Original source A new study has found that the summer solstice acts as a 'starting gun' to synchronize beech tree reproduction across vast distances in Europe, affecting ecosystem functions.
Published Study brings scientists a step closer to successfully growing plants in space
(via sciencedaily.com) Original source New, highly stretchable sensors can monitor and transmit plant growth information without human intervention. The polymer sensors are resilient to humidity and temperature, can stretch over 400% while remaining attached to a plant as it grows and send a wireless signal to a remote monitoring location, said a chemical and biomolecular engineering professor.
Published Alaska dinosaur tracks reveal a lush, wet environment
(via sciencedaily.com) Original source A large find of dinosaur tracks and fossilized plants and tree stumps in far northwestern Alaska provides new information about the climate and movement of animals near the time when they began traveling between the Asian and North American continents roughly 100 million years ago.