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Categories: Biology: Botany, Biology: Molecular
Published A simple and robust experimental process for protein engineering
(via sciencedaily.com) Original source A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.
Published Exploring arctic plants and lichens: An important conservation baseline for Nunavut's newest and largest territorial park
(via sciencedaily.com) Original source A comprehensive study of the floristic diversity of Agguttinni Territorial Park, Nunavut's newest and largest Territorial Park, has documented 141 vascular plant, 69 bryophyte, and 93 lichen species from this unique protected area on northern Baffin Island. Through a combination of extensive fieldwork in 2021 and examination of hundreds of existing herbarium specimens, the authors have documented species newly reported for Baffin Island and have crafted a biodiversity baseline important for park management and conservation.
Published Scientists find weak points on Epstein-Barr virus
(via sciencedaily.com) Original source Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.
Published How a natural compound from sea squirts combats cancer
(via sciencedaily.com) Original source Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.
Published Rainforest's next generation of trees threatened 30 years after logging
(via sciencedaily.com) Original source Rainforest seedlings are more likely to survive in natural forests than in places where logging has happened -- even if tree restoration projects have taken place, new research shows.
Published Researchers uncover protein responsible for cold sensation
(via sciencedaily.com) Original source Researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.
Published Research sheds light on new strategy to treat infertility
(via sciencedaily.com) Original source New research describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos. The technique could be used by women of advanced maternal age or for those who are unable to produce viable eggs due to previous treatment for cancer or other causes. It also raises the possibility of men in same-sex relationships having children who are genetically related to both parents.
Published New study discovers how altered protein folding drives multicellular evolution
(via sciencedaily.com) Original source Researchers have discovered a mechanism steering the evolution of multicellular life. They identified how altered protein folding drives multicellular evolution.
Published Mutation solves a century-old mystery in meiosis
(via sciencedaily.com) Original source A team deciphers complicated mechanism underlying genetic diversity.
Published Researchers develop artificial building blocks of life
(via sciencedaily.com) Original source For the first time, scientists have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory.
Published Vitamin A may play a central role in stem cell biology and wound repair
(via sciencedaily.com) Original source Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair.
Published The Malaria parasite generates genetic diversity using an evolutionary 'copy-paste' tactic
(via sciencedaily.com) Original source All modern Plasmodium falciparum, the deadliest malaria parasite in humans, are descendants of one initial infection and so are very closely related, with relatively limited genetic differences. A long-standing mystery in the field has revolved around a very few locations in the P. falciparum genome where there are 'spikes' of mutations -- far more than anywhere else. Researchers have identified two genes in which these unusual mutation spikes result from DNA being copied and pasted from one gene to another.
Published Earth's earliest forest revealed in Somerset fossils
(via sciencedaily.com) Original source The oldest fossilized forest known on Earth -- dating from 390 million years ago -- has been found in the high sandstone cliffs along the Devon and Somerset coast of South West England.
Published Cracking epigenetic inheritance: Biologists discovered the secrets of how gene traits are passed on
(via sciencedaily.com) Original source A research team has recently made a significant breakthrough in understanding how the DNA copying machine helps pass on epigenetic information to maintain gene traits at each cell division. Understanding how this coupled mechanism could lead to new treatments for cancer and other epigenetic diseases by targeting specific changes in gene activity.
Published First heat map for individual red blood cells
(via sciencedaily.com) Original source Entropy is often associated with disorder and chaos, but in biology it is related to energy efficiency and is closely linked to metabolism, the set of chemical reactions that sustain life. An international research team has now developed a novel methodology for the measurement of entropy production at the scale of a nanometer, meaning one-billionth of a meter. The new approach enabled the scientists to measure the heat flow, known as the entropy production rate, of single red blood cells.
Published The world's most prolific CO2-fixing enzyme is slowly getting better
(via sciencedaily.com) Original source New research has found that rubisco -- the enzyme that fuels all life on Earth -- is not stuck in an evolutionary rut after all. The largest analysis of rubisco ever has found that it is improving all the time -- just very, very slowly. These insights could potentially open up new routes to strengthen food security.
Published Marine algae implants could boost crop yields
(via sciencedaily.com) Original source Scientists have discovered the gene that enables marine algae to make a unique type of chlorophyll. They successfully implanted this gene in a land plant, paving the way for better crop yields on less land.
Published Universal tool for tracking cell-to-cell interactions
(via sciencedaily.com) Original source An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.
Published Synthetic gene helps explain the mysteries of transcription across species
(via sciencedaily.com) Original source 'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.
Published Decoding the language of epigenetic modifications
(via sciencedaily.com) Original source Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study now provides important new insights into how complex epigenetic modification signatures regulate the genome. This study will pave the way for new treatments of diseases caused by faulty epigenetic machineries.