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Categories: Biology: Botany, Biology: Molecular

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A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease and several types of cancer.

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Using data from 6,645 camera traps across the United States, researchers mapped populations of 25 mammal species. They determined that climate, not human activity, was the primary factor in mammals deciding where to live.

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Lampreys are one of only two living jawless vertebrates Jaws are formed by a key stem cell population called the neural crest New research reveals the gene regulatory changes that may explain morphological differences between jawed and jawless vertebrates.

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An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.

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Reforestation in low- and middle-income countries can remove up to 10 times more carbon dioxide from the atmosphere at lower cost than previously estimated, making it a potentially more effective option to fight climate change. Most current reforestation programs focus on tree planting alone, but the study estimates that nearly half of all suitable reforestation locations would be more effective at sequestering carbon if forests were allowed to grow back naturally.

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Using trees as a cost-effective tool against climate change is more complicated than simply planting large numbers of them, an international collaboration has shown.

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New research has advanced our knowledge of multiple roles for PTPRK, a receptor tyrosine phosphatase linked to the regulation of cell-cell adhesion, growth factor signalling and tumor suppression. Through a characterization of the function of PTPRK in human cell lines and mice, the team distinguished catalytic and non-catalytic functions of PTPRK. The findings extend what is known about the signalling mechanisms involving PTPRK as a phosphatase and its role in colorectal health but also shed new light on the extent of its function via non-catalytic signalling mechanisms.

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Tree bark surfaces play an important role in removing methane gas from the atmosphere.

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Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists have used cryo-electron microscopy to observe how lipids and proteins at the plasma membrane interact and react to mechanical stress. This work shows that, depending on conditions, small membrane regions can stabilize various lipids to trigger specific cellular responses. These discoveries confirm the existence of well-organized lipid domains and begin to reveal the role they play in cell survival.

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Researchers demonstrate that the plant hormone gibberellin (GA) is essential for the formation and maturation of nitrogen-fixing root nodules in legumes and can also increase nodule size.

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New drug that disrupts two cellular targets would make it much harder for bacteria to evolve resistance.

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Trees in the Brazilian Atlantic Forest are migrating in search of more favourable temperatures with species in mountain forests moving uphill to escape rising heat caused by climate change.

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A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionize the response to future pandemics, researchers report.

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Scientists have succeeded in pinpointing the neurons within a female fruit fly's brain that respond to signals from the male during mating.

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Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease. Now, research uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts, with the potential to aid in developing novel antiviral treatments and vaccines.

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A bitter taste is traditionally considered a warning sign of potentially toxic substances. But not all bitter substances are harmful. For example, some peptides and free amino acids taste bitter, even though they are non-toxic, nutritious and sometimes even vital for humans. A new study now offers an explanation for this seemingly paradoxical phenomenon.

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A little leg may reveal something big about how closely related insect species can drastically differ in body shape, according to a new study. The team imaged live cells of fruit flies in the last stages of development over several days and found a new structure that appears to help guide a section of the leg into its final shape.

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New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.

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Imagine a small fruit that tastes like a cross between a tomato and a pineapple, wrapped in its own natural paper lantern. That's the groundcherry (Physalis grisea) -- a little-known relative of tomatoes that's been quietly growing in gardens and small farms across North America for centuries. Now, this humble fruit is getting a 21st-century upgrade thanks to some cutting-edge genetic research.

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Researchers have uncovered an under the sea phenomenon where coral-destroying crown-of-thorns starfish larvae have been feasting on blue-green algae bacteria known as 'sea sawdust'.