Showing 20 articles starting at article 721
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Categories: Biology: Microbiology, Energy: Alternative Fuels
Published Compound vital for all life likely played a role in life's origin
(via sciencedaily.com) Original source A chemical compound essential to all living things has been synthesized in a lab in conditions that could have occurred on early Earth, suggesting it played a role at the outset of life.
Published Copies of antibiotic resistance genes greatly elevated in humans and livestock
(via sciencedaily.com) Original source Researchers have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. Bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance genes which are linked to 'jumping genes' that can move from strain to strain. Duplicate genes provide a mechanism for resistance to spread and enable evolving resistance to new drugs.
Published Metabolic diseases may be driven by gut microbiome, loss of ovarian hormones
(via sciencedaily.com) Original source Mice that received fecal implants from donors that had their ovaries removed gained more fat mass and had greater expression of liver genes associated with inflammation, Type 2 diabetes, fatty liver disease and atherosclerosis. The findings may shed light on the greater incidence of metabolic dysfunction in postmenopausal women.
Published Damage to cell membranes causes cell aging
(via sciencedaily.com) Original source Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging.
Published Scientists discover link between leaky gut and accelerated biological aging
(via sciencedaily.com) Original source A professor has demonstrated a connection between viral damage to the gut and premature biological aging.
Published Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
(via sciencedaily.com) Original source About a decade ago, researchers began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing the microbes. Not good if the objective of the project was to harness the metabolism of living bacteria to produce electricity.
Published High resolution techniques reveal clues in 3.5 billion-year-old biomass
(via sciencedaily.com) Original source To learn about the first organisms on our planet, researchers have to analyze the rocks of the early Earth. These can only be found in a few places on the surface of the Earth. The Pilbara Craton in Western Australia is one of these rare sites: there are rocks there that are around 3.5 billion years old containing traces of the microorganisms that lived at that time. A research team has now found new clues about the formation and composition of this ancient biomass, providing insights into the earliest ecosystems on Earth.
Published Snaking toward a universal antivenom
(via sciencedaily.com) Original source Scientists discovered antibodies that protect against a host of lethal snake venoms.
Published Revealing what makes bacteria life-threatening
(via sciencedaily.com) Original source Researchers have discovered that a mutation in the cellulose making machinery of E. coli bacteria allows them to cause severe disease in people -- 'good' bacteria make cellulose and 'bad' bacteria can't. The mutations stopped the E. coli making the cell-surface carbohydrate cellulose and this led to increased inflammation in the intestinal tract of the host, resulting in a breakdown of the intestinal barrier, so the bacteria could spread through the body. Understanding how bacteria spread from intestinal reservoirs to the rest of the body is important in preventing infections and tackling antibiotic resistance.
Published New evidence shows UK solar parks can provide for bees and butterflies
(via sciencedaily.com) Original source A new study shows that UK solar parks, if managed correctly, can provide vital resources to help stem the decline in the nation's bees and butterflies. The new research provides peer-reviewed field data of insect pollinators at solar parks in the UK, covering 15 sites.
Published Kiss-and-tell: A new method for precision delivery of nanoparticles and small molecules to individual cells
(via sciencedaily.com) Original source The delivery of experimental materials to individual cells with exactness and exclusivity has long been an elusive and much sought-after ability in biology. With it comes the promise of deciphering many longstanding secrets of the cell. A research team has now successfully shown how small molecules and single nanoparticles can be applied directly onto the surface of cells. In the study the scientists describe their technique as a ' kiss' (microkiss) -- an easy and cost-effective new method, unlocking new possibilities in single-cell science with a view towards next generation therapeutic applications.
Published Toxic elements found in stranded whales, dolphins over 15 years
(via sciencedaily.com) Original source Researchers evaluated the prevalence, concentration and tissue distribution of essential and non-essential trace elements, including heavy metal toxicants in tissue (blubber, kidney, liver, skeletal muscle, skin) and fecal samples collected from 90 whales and dolphins stranded in Georgia and Florida from 2007 to 2021.
Published Revolutionary breakthrough in solar energy: Most efficient QD solar cells
(via sciencedaily.com) Original source A research team has unveiled a novel ligand exchange technique that enables the synthesis of organic cation-based perovskite quantum dots (PQDs), ensuring exceptional stability while suppressing internal defects in the photoactive layer of solar cells.
Published Scientists invent ultra-thin, minimally-invasive pacemaker controlled by light
(via sciencedaily.com) Original source A team of researchers has developed a wireless device, powered by light, that can be implanted to regulate cardiovascular or neural activity in the body. The feather-light membranes, thinner than a human hair, can be inserted with minimally invasive surgery and contain no moving parts.
Published Detecting pathogens faster and more accurately by melting DNA
(via sciencedaily.com) Original source A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
Published 'The future is fungal': New research finds that fungi that live in healthy plants are sensitive to climate change
(via sciencedaily.com) Original source Findings more than a decade in the making reveal a rich diversity of beneficial fungi living in boreal forest trees, with implications for the health of forests.
Published Engineering a coating for disease-free produce
(via sciencedaily.com) Original source Texas A&M researchers combine food-grade wax with essential oils to defend produce from bacteria.
Published Bridging diet, microbes, and metabolism: Implications for metabolic disorders
(via sciencedaily.com) Original source Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.
Published Photosynthetic mechanism of purple sulfur bacterium adapted to low-calcium environments
(via sciencedaily.com) Original source Purple sulfur bacteria (PSB) convert light energy into chemical energy through photosynthesis. Interestingly, certain species can photosynthesize even in environments with low-calcium levels. Using cryo-electron microscopy, researchers unveiled the structure of light-harvesting complexes and elucidated the mechanism that facilitates photosynthesis under low-calcium conditions.
Published Breakthrough in developing the PD-1-enhanced DNA vaccine for over 6-year cART-free AIDS prevention and virologic control
(via sciencedaily.com) Original source Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy.